vortex30
Bluelighter
I realize these two questions are not exactly pharmacokinetics questions but I couldn't really think of a better word, and they aren't terribly advanced either but I figure this is the best place where I will get detailed and accurate responses.
1) When we IV we use a filter to filter out most of the unsoluble matter in the solution, and yes we shouldn't really be IVing pills such as OxyContin but naturally many do and so have I more recently. Now my question is that naturally not all of the unsoluble matter will be filtered and a small portion will make it into the shot. What exactly is our body's response to these solids in our circulatory system? Does it stay there forever or is there some way that it does get excreted eventually and if so what is the mechanism behind this? I suppose it would vary depending on the specific solids that get in, but as best as you can answer in a general way.
2) Shooting into arteries is a very, very bad thing to do apparently and I sort of understand the reasons why because arteries get smaller and smaller into capillaries and eventually it can become too small for the matter to pass through thus it gets clogged and swollen. That makes sense. But when you hit a vein, yes the veins get bigger and bigger until the heart, but then your shot is carried out through arteries...Wouldn't those same particles eventually make it to a capillary that is too small for them to pass through anyways, just more delayed and in a less specific area?
Thanks for your responses, been wondering about these two things for a while.
1) When we IV we use a filter to filter out most of the unsoluble matter in the solution, and yes we shouldn't really be IVing pills such as OxyContin but naturally many do and so have I more recently. Now my question is that naturally not all of the unsoluble matter will be filtered and a small portion will make it into the shot. What exactly is our body's response to these solids in our circulatory system? Does it stay there forever or is there some way that it does get excreted eventually and if so what is the mechanism behind this? I suppose it would vary depending on the specific solids that get in, but as best as you can answer in a general way.
2) Shooting into arteries is a very, very bad thing to do apparently and I sort of understand the reasons why because arteries get smaller and smaller into capillaries and eventually it can become too small for the matter to pass through thus it gets clogged and swollen. That makes sense. But when you hit a vein, yes the veins get bigger and bigger until the heart, but then your shot is carried out through arteries...Wouldn't those same particles eventually make it to a capillary that is too small for them to pass through anyways, just more delayed and in a less specific area?
Thanks for your responses, been wondering about these two things for a while.
