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Dissociatives Question on proper DXM Microdosing

jeebies444

Greenlighter
Joined
Apr 9, 2025
Messages
2
Long time lurker - first time poster. Will be somewhat of a long post but any and all guidance from those more experienced in this space would be v much appreciated.

Background context: I am a 30 year old male, 220 pounds, and have been recreationally/therapeutically using DXM on and off for approximately 15 years now. However the last year and a half has been my most prolonged consistent use. For the years prior to that I would occasionally (2 to 4 times a year) take a ~300mg dose, which at the time would be somewhere around 3mg/kg for me or somewhere in the middle of the 2nd plateau.

My most recent regiment and stack is as follows:
180-270mg DXM split out in 2-3 doses (60-90mg every 4 to 6 hours)
200mg caffeine
4-8mg nicotine
1g l-theanine

I have been taking this stack more or less daily for the last 4 months, taking a tolerance break every Sunday but have not really taken any tolerance breaks longer than 72 hours during this time period. This stack allows me to feel a general sense of warm euphoria, connectedness, alignment with what we could generally describe as higher/loftier virtues of consciousness (love, service to God/source/consciousness and those around us, humor, playfulness etc. etc.), and an incredibly consistent and reliable ability to focus and concentrate intensely on whatever it is I'm working on or whoever I'm present with. Just a complete and total sense of effortless presence in every endeavor or encounter. The issue I've been running into is that I have observed that over this time period I will generally uptick the dosage of DXM to maintain a certain level of potency where I feel almost too disinhibited and untethered from true material reality, just a general sense of excessively prolonged lack of groundedness. In this state, I feel it incredibly difficult to maintain presence and lucidity in what's going on around me in a literal material sense and this presents itself in a couple of different ways. I come off as scatterbrained, my speech is slurred and/or strained, I have a difficult time fully comprehending or maintaining attention on whatever is happening in that current point in time, essentially the exact opposite of the enjoyable heightened awareness state I mostly find myself in most of the time when taking this stack.

I have a series of questions for anyone and everyone here who's more well versed in the pharmacology of DXM and related dissociatives. My primary concern is that this prolonged use at the dosages I've mentioned above may have long term detrimental neurocognitive side effects. Is my issue that I'm just not taking sufficiently long enough tolerance breaks to allow myself to return to more "grounded" baselines when fully sober? Are there other practices (breathwork for example?) that I can supplement here that will help balance things? Is there perhaps another dissociative that I should consider exploring that has similar positive effects to DXM without some of the more unsavory side effects that I've mentioned? Is it possible to maintain this psuedo-microdosing regiment indefinitely, or is this really not sustainable long term and I need to strongly consider finding a practice not rooted in supplementing dissociative substances and follow the age old McKenna adage of hanging up the phone once I've gotten the message?

I have heard of several accounts where at some point or another many Dexheads eventually reach a point in their dynamic with the substance where the "magic" just wears off and they graduate to something else to acquire the same effect. Again - any insights you all may share would be sincerely appreciated!
 
Idk that sounds more like a first plat dose than a micro dose to me personally, but I might have a different metabolism.
 
Idk that sounds more like a first plat dose than a micro dose to me personally, but I might have a different metabolism.
Yes I would agree this definitely straddles somewhere between 1st and 2nd plateau depending on timing of dosing. I use the term microdosing loosely as to me I wouldn't consider the effects of those plateaus to be full blown "trips" where there's an appreciable comeup, peak, and comedown etc. etc. It's a fairly static and consistent mellow sort of intoxication (up until the latter stages I described towards the end that I'm trying to circumvent.)
 
i think this thread is probably gonna confuse some people at first with the term microdosing cause there is a newer psych med that i believe is prescribed every day that's only like 40 or so mgs of dxm and another drug twice a day... i don't know much about it other than i remembered it being a dose not much higher than for a cough twice a day, but this is a google "Dextromethorphan and bupropion combination is used to treat major depressive disorder (MDD). This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Tablet, Extended Release."

pretty easy to tell what the OP is asking though... i really have no advice for taking DXM. just thought i'd comment on the microdosing... i feel like prescribed doses of dxm can make some people a little loopy, especially kids... there was a poster talking about dosing DXM a lot and they were saying they get their blood checked and go to the doctors all the time, so they know their organs aren't failing.. they were using a pretty heavy amount. i see that person on the site every now and then i think, but they haven't really been posting about it.. idk. i've known some people IRL that were heavy DXM users and people usually describe some brain fog. i can't really say... not a disassociative, but do you do shrooms? maybe look into those. probably illegal where you are, but they aren't too hard to source in most places and you can even just order the stuff to grow them online to a lot of jurisdictions if you keep it to yourself. some places you're even allowed to trip in public and give out shrooms and it's not illegal. five cities in massachusetts USA i know did this since sometime around 2020. everybody knows about calorado too... got to be careful when getting into psychedelics though. hard for me to recommend random people i don't know start using them, but i know if you read deep enough into the net you'll eventually see that shrooms are a healthier drug than a lot of other options. most people do well with shrooms. every now and then people get mental health issues. i don't see it being much different than dxm though as far as people having mental trouble. i have heard of people freaking out the same way on both drugs.
 
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