So i did some reading and when you snort a drug it surpasses your first pass metabolism, meaning the liver enzymes don't break down the chemical it just goes straight to your blood stream. How is the chemical broken down then, it has to be processed some how isn't the liver still responsible for that? The reason i ask is because i don't really want to mix 2 of the same enzyme inhibitors, specifically cyp2d6. If i'm on something that mildly inhibits 2d6 and i snort another chemical that also inhibits 2d6 then okay right, because snorting doesn't go through the liver enzymes??
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N&PD Moderators: Skorpio
Question on how Snorting works / passing liver enzymes
- Thread starter F1n1shed
- Start date
sekio
Bluelight Crew
SNorting a drug just means it is delivered into the blood before it hits the liver.
When you eat a drug it must pass through your liver before it hits the blood. Other routes of administration bypass this.
If a drug inhibits a liver enzyme it will just take longer for the inhibition to take effect if you snort it rather than eat it. The drug will still have all the same f/x, it will just take longer to build up in your liver.