Question about sublingual administration...please help.

[PsychedelicLove]

Today I stumbled upon a bottle of lorazepam tablets, 0.5mg each. I plan on taking some tonight, but before I do so I want to ensure that I am administering the drug in a way that allows for maximum efficiency. That being said, I have a question regarding sublingual administration: Must the pills be formulated specially for sublingual absorption in order to work this way? I don't believe the pills I have are designed specifically for sublingual use, but I have heard plenty of posts on this site that suggest sublingual administration is effective for any pills. Any answers would be greatly appreciated.

 

[Swimmingdancer]

Not just any pills can be taken sublingually, but for benzodiazepines I believe the consensus is that they can usually be taken sublingually whether it is a sublingual formulation or not. Personally I have found it to not make much of a difference though, aside from maybe a slightly faster onset.

 

[Cloroxtastebad]

As said above, there are many pills that cannot be taken sublinguallly. However, lorazepam you can certainly take orally or sublingual. As far as effects go, you may notice a faster onset and slightly higher peak effects. I wouldnt expect too much of an increase in effects however. From personal experience, i havnt noticed any benefits taking benzos subligually.

 

[mrflowers00]

when i was prescribed lorazepam i took it sublingual but i just thought they tasted good and maybe hit a little faster but they don't work any better that way

 

[Cloroxtastebad]

when i was prescribed lorazepam i took it sublingual but i just thought they tasted good and maybe hit a little faster but they don't work any better that way

I agree with this, the faster onset can be nice but ive never felt that the peak effects were any different. I would think the peak blood plasma levels would be increased because of the speed in whichtbe drug is absorbed sublingually. However I don't think its enough to notice much of a difference

 

[deficiT]

Yeah sublingual is good for lorazepam, just a faster onset

 

[dais]

Not just any pills can be taken sublingually, but for benzodiazepines I believe the consensus is that they can usually be taken sublingually whether it is a sublingual formulation or not. Personally I have found it to not make much of a difference though, aside from maybe a slightly faster onset.

this.