Pyrolysis(smoking) vs. intrathecal injection

[bupropion]

Which of these methods of administration delivers drugs to the brain faster (I've read that both are faster than IV provided the smoking is done very rapidly of course) ?

Has anyone experienced a fast intrathecal injection? What is it like?

On a side note I'd imagine that it is not possible to receive such an injection while standing up as with IV (when you have a needle with a canula attached already in your arm). When this was done with me it seemed to amplify the ffects of the Valium I was given.

 

[vecktor]

I would expect with intrathecal injection into the cerebrospinal fluid is slowed because the substance has to diffuse through the CSF from the site of injection there is some active flow but mostly it looks like passive diffusion. smoking on the other hand gives very high blood levels which drives the absorbtion from the capillaries through the BBB over a wide surface area.
It is more important to consider the rate of increase rather than the speed of onset from administration.

intracranial perfusion seems the way to go, better still remove the top of the skull and the meninges and fit a glass top with inlet and outlet ports filled with isotonic sterile saline. one obviously would have to wear a hat outdoors to prevent your brain getting sunburn. but it would greatly facilitate loperamide abuse.

 

[SKL]

Intrathecal injection is just ASKING for possibly fatal encephalitis / meningitis. Please don't do it, seriously. It's a risky enough procedure in the hospital, let alone at home with whatever you're planning on putting there. Also, not all drugs, and not all solutions, can be administered intrathecally: morphine, for example, needs to be "preservative free" in order to be given, and so on, and so forth. Normal saline that you would easily have access to for diluting things is not preservative free, and God knows what's in tap water. Seriously, folks, this is one to leave to the professionals. If you ARE a professional, I certainly hope you exercise extreme care.

 

[vecktor]

Intrathecal injection is just ASKING for possibly fatal encephalitis / meningitis. Please don't do it, seriously. It's a risky enough procedure in the hospital, let alone at home with whatever you're planning on putting there. Also, not all drugs, and not all solutions, can be administered intrathecally: morphine, for example, needs to be "preservative free" in order to be given, and so on, and so forth. Normal saline that you would easily have access to for diluting things is not preservative free, and God knows what's in tap water. Seriously, folks, this is one to leave to the professionals. If you ARE a professional, I certainly hope you exercise extreme care.

even professionals get this one wrong and paralyse people... not good which is why skull removal is the way to go, I'm sure it could be done with a dremel multitool and a fish bowl.

 

[fastandbulbous]

^ Or even a modified version of the can opener that you just sit on top, press the button and it moves itself around the edge of the can.

Could you not just use a larger made pair of scissors that you take the tops off soft boiled eggs with?

 

[leungkachong]

Along with all the important ideas for home mutilation, I thought I'd mention that pyrolysis is not the part of the process that gets you high. That is the fire/heat (pyro) resulting in the decomposition (lysis) of your drugs.

 

[Jamshyd]

This thread needs to be shipped to Best of Bluelight

ps. *hugs* for leungkachong, miss ya' .