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RCs Pyrazolam Megathread

Currently on 30mgs Valium per day, My Ideal script would be 8mg Xanax per Day with a 10mg Zolpidem at night lol, But it's Pyraz for now just recieived my 250 :)
 
Has anyone taken pyrazolam before smoking weed? I'm hoping it may relieve some anxiety
 
Sounds like this could also be useful for managing a stim comedown without falling asleep. I get really sketchy after meph or coke sessions where I have to stop re-dosing and stay awake for a while.
 
I'm looking into buying the drug in powder form and it seems to be surprisingly cheaper than tablets

I aint seen it in powder form on my usual vendors, soon as I see that I'll be grabbing it.

There are vendors stocking it, but you have to be an 'advanced customer', since many vendors have such an section for especially 'dangerous' chemicals with dosages as low as 1-2mg (which is, as i think absolutely reasonable). I just think substances like Etizolam powder or things like 3-MeO-PCP/PCE should just not be made available for each and everyone.
 
Yeah the fact that Etizolam powder is easily available in my opinion is extremely dangerous. Pyrazolam are quality , Ive been taking 4mg upon wakening with cup of tea in bed (the mrs :)) and soon as they hit me, on with my day, they last on average 7 hours I reckon, I've got 2000 of them coming tomorrow :) Happy Days :D
 
Cheers, I'm taking a night off. So far I feel fine, but they're calling my name....
Funnily enough i can take or leave the etiz, it's the pyraz i prefer.

Edit: damnit! I gave into temptation and took some pyraz. I have twelve left; I'll take them tonight, and not be able to have anymore if I like it or not. (I'm broke for a week). I didn't have a seizure or anything; just knowing they were there drove me crazy....
 
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I've just bought ten of these to give them a try. I have zero benzo tolerance so this should be just the thing for chilling me out and getting rid of some stress and tension.
 
Not to downplay benzo addiction or withdrawal at all- I've had 'minor' benzo withdrawal & it was worse than 'upper moderate' opiate withdrawal in sheer unpleasantness (different symptoms obviously, but you know)- but it's a hell of a lot harder to get addicted to benzos than it is to get addicted to opiates. MUCH MUCH harder.

To put things into context- under medical advice (you're having a mental breakdown and genuinely need benzos) it is perfectly acceptable to take a course of therapeutic doses for 1-3 months, though they should not be immediately withdrawn & rather tapered down. If you have been taking therapeutic doses (no more than the equivalent of ~20mg of diazepam a day) for less than 3-4 months you will NOT experience benzo withdrawal. You will however experience rebound effects that can be quite unpleasant for 1-2 weeks (insomnia, anxiety, occasional mild tremors) which is wise to both taper off benzos as well as making a genuine effort to not 'rely' on benzos. To continue my 'mental breakdown' example, even if you've been prescribed 10mg diazepam X2 daily you should always make an effort to only take them if you need them- on a good day you should try going without or halving your dose...due to most benzos long half-lives you're unlikely to be completely without benzo metabolites so regularly missing a day is gonna do more good than harm.

Now, everything that I've said only applies to people who are either prescribed short-term (1-3 months) daily benzos or who are prescribed benzos long-term to be used as needed...that is more or less how benzos are prescribed these days, it is exceedingly rare for someone to be put on long-term daily benzo use these days (though it does seem to be far more common in the USA, but that has to do with their entirely privatised medical system rather than best practice).

The whole point of being prescribed benzos is to help get into a situation where you don't need benzos...it's kinda ironic that benzos are considered excellent anti-anxiety medications (despite their addiction liability) for the very reason that- in conjunction with therapy- taking benzos in a controlled manner result in you not needing to take benzos anymore!

Now, if you're abusing benzos (i.e. rapidly developing a massive tolerance due to huge doses/redosing) the situation is different...but it still takes quite a long time of serious benzo abuse in order for you to experience minor withdrawal (in addition to normal rebound anxiety/insomnia). To use my experience as any example-

I used a LOT of benzos when I was kicking opiates- for ~10 days I was taking 60mg of diazepam a day + a minimum of 15-25mg of Midazolam plugged (equiv to 45-75mg oral/equal to 60-90mg diazepam) to sleep with 250mg of temazepam also consumed during the 'peak', then I continued taking 20-40mg of diazepam for another 2 weeks. By this point I was completely past the opiate withdrawal and I ran out of diazepam/midazolam & despite my insane doses I only suffered rebound insomnia/anxiety, which was barely noticeable as I was still sleeping badly anyway. I went for ~10 days with no benzos then I obtained 500mg of pure alprazolam powder...I'm not a big fan of alprazolam, I don't like the lack of sedative effects, but the PAWS were starting to hit hard and I went through the alprazolam in about 35 days, averaging 10mg a night to sleep...but when I was having bad opiate cravings/going out on the smash I'd take 20-30mg over the night in 10mg doses. One infamous night I took 40mg...fucking chaos man.

Anyway, once I started to run out I decided that I had to try to taper and not buy any more benzos. I managed to taper down to ~5mg a night to sleep then I had like 3-4 days of bag licking, so 1-2mg doses...then it was cold turkey, just a fat ounce of beautifully manicured cannabis. That DID cause withdrawal, but they were at the minor end of benzo withdrawal- but still worse than minor opiate withdrawal by a long shot. I literally didn't sleep at all for 3 days then only slept in 2-3 hour blocks for about a week...it was actually bad enough that on the third night I actually went and bought a small amount of methadone just so I could sleep (did the trick & didn't cause a relapse) because I was starting to hallucinate slightly from sleep deprivation. I was also angsty as hell, it was like being a teenager again. But you've gotta remember I had been taking the equivalent of 200mg of diazepam nightly, just so I could sleep- I'd take 30mg of alprazolam, snort some ketamine and smoke some spliff and try to convince myself I was nodding at least once a week. I was a fucking trainwreck- as far as I'm concerned I got off light considering how badly I abused benzos, particularly alprazolam (which is STILL one of my least favourite benzos FFS!!)

You're smart to be cautious when it comes to messing around with benzos, but as long as you use a little common sense you shouldn't have any problems. Don't take them daily, even at therapeutic doses, for more than week at very most...and if you have a particular need for them (e.g. opiate withdrawal, death of loved one etc) aim to take them for no more than 1-3 months and try hard to be honest with yourself about whether or not you actually need to take benzos today.

Withdrawal comes on considerably faster if you obviously abuse them- if you are regularly taking megadoses, particularly of long acting benzos, you are far more likely to experience 'genuine' withdrawal in as little as a month of constant use. Always taper off benzos, it will make the withdrawal considerably less unpleasant/dangerous.

Seizures are NOT common unless you have been dependent on benzos for a prolonged period of time- if you are genuinely at risk of having a seizure due to benzo withdrawal you will know. Why? Because you have either been taking benzos multiple times a day for 6 months + or you have been abusing the fuck out of them, taking ten, twenty times the normal dose multiple times a week. You will have bruises on your shoulders from clipping the edges of doorways, you will constantly be hiding things and forgetting where they are, your pants will be covered in stains from various stuff that you've spilt on yourself and your erratic and unpredictable behaviour will be alienating your friends.

Unless you're experiencing severe benzo withdrawal you are very unlikely to have a seizure...and you're gonna know if you'll experience severe withdrawal if you go without! Seriously, I think half the time people use the 'threat of seizures' as a justification for not doing anything about their benzo dependence until it reaches a point where they are at risk of having seizures!

I'm not saying it doesn't happen, but seizures are very rare unless you're either heavily addicted or you've been dependent for ages.
 
I was surprised to hear the length of time it can take to become dependent on benzo's. Of course, psychological dependence can occur a hell of a lot more quickly; they are very "morish" , I guess. When I did my in-patient detox for alcohol they gave me large doses of librium on a 10 day taper. The detox itself was painless, but I was highly anxious for months afterwards and I've know idea why. I always assumed it was the librium, but I guess that's not it, considering my use was short-term.

Are gabba b agonists effective for withdrawing from gabba a agonists btw? I assumed this was the reason they give benzos to people in alcohol dt's....
If so, maybe the reverse is true; maybe using a gaba b agonist (phenibut for example) could help detox from a benzo.

Of course, I know jack shit about chemistry.

Edit: I wonder why big pharma don't have their grasping claws on these things yet? If they do, we can kiss goodbye to our beloved RC suppliers. Possibly a patent thing...?
 
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limonov-

Thank you for your story. That is crazy - you seem like a super-strong person to go through that.

You mention continue use of benzos, ie; continued use for 1-3 months. Now , What is your opinion on using them occasionally for extended periods (years)? For instance, once a week, or once every two / three weeks- even months, for when it's really needed. like going on a first date, or meeting girls.

no benzo works for me, except Valium and Etizolam. Valium has a very small anti-anxiety effect, so I don't do it any more, but 1mg of Etizolam does wonders. Last time i did Etizolam was 14 days ago. No withdrawal.

I think if suffer from depression, always thought it was anxiety though. I masked it for 3 years with opiates- I never got addicted, I kept use to once a week for when I went out to parties or something social.. Amazing?

I am now doing the same with Etizolam as I just don't want to fall into a trap with opiates.


Maybe I should talk to a doctor, but what can they really do? Nothing I'd assume

Are there any anti-depressants that work just like tramadols snri effect? Are there anti-depressants that you don't have to take everyday for them to work? I don't like putting drugs into my body every single day. But tramadol's snri effects seems to work right off the bat - And I really miss that. Not the opioid effect.
 
Hi there zzz101, there are many, many ssri/snri's on the market right now; they are the decades "wonder drug", after all, and are being pushed heavily by the pharm companies. I've no idea the difference between SSRI and SNRI drugs, but I've been on SSRI's for six years now, and they're excellent for depression, and I mean great.

I was originaly taking citralopram, but they made me restless and it was hard to sleep on them. I now take mirtazipine, they are a relatively poweful sedative, and also an appetite enhancer. (I've gained weight!)

None of these drugs (ssri's at least) kick in instantly; it can take quite a long time for the brain to regulate it's serotonin to normal levels, even with ssri assistance)For me, it took around 6 weeks, but the effects can last months, even if you stop taking the drug, so it's not vital you take it every day.
 
Hi there zzz101, there are many, many ssri/snri's on the market right now; they are the decades "wonder drug", after all, and are being pushed heavily by the pharm companies. I've no idea the difference between SSRI and SNRI drugs, but I've been on SSRI's for six years now, and they're excellent for depression, and I mean great.

I was originaly taking Citralopram, but they made me restless and it was hard to sleep on them. I now take mirtazipine, they are a relatively poweful sedative, and also an appetite enhancer. (I've gained weight!)

None of these drugs (ssri's at least) kick in instantly; it can take quite a long time for the brain to regulate it's serotonin to normal levels, even with ssri assistance)For me, it took around 6 weeks, but the effects can last months, even if you stop taking the drug, so it's not vital you take it every day.
My first SNRI was Effexor, It took effect pretty quick but my system had to get used to it. The first few days i felt like I took a very low dose MDMA I even had dilated pupils, which was awkward as people around me started to notice and thought I was also more customer friendly than usual =)
After a few weeks it evened out and worked great especially at dosage above 150mg (aditional norepenephrine action i believe)
BUT... Forget a daily dose and expect to pay the price, instant withdrawal syndrome resulting in freaky brain-zaps, some head aches and an overall hung over miserable feeling.

I have ADD and during this time I was also taking Concerta (Methylphenidate) during this period of about 8 years.

If I took my meds and made sure to have my precription renewed in time, (weekends without Effexor are hell and I also remember raising hell at the pharmacy when my script wasn't ready too)
I was on top of the world. Things were going better and better.
Only...eventually after a year or so, my girlfriend started complaining I was losing interest in her.. Although this had multiple reasons... decreased libido was part of it.

I figured what the hell everything is going super smooth, it's time to quit and get on with business, so I did. A week taper halving my dose and then a few days prozac. I was my usual self and behaving like the old dog again, gf didn't complain neither did anyone else.
Things seemed fine. In hind sight they were not.

Depression and social anxiety slowly crept back in and I became less confident, this combined with a fresh coke habit which made me a bit paranoid, I fucked up at a lot of things while still riding the wave to sucess that had already lost momentum.

Anyway...almost back on topic guys...
I figured I made a bad desicion so started Citalopram an SSRI my doc said would probably keep my libido intact..It did but didn't do anything else either, thinking it might take some time again I stayed on it for quite a while, but eventually I was still not the vibrant and more confident me and was dissatisfied with the results I got from Citalopram.(except the nice vivid dreams)

As I was no longer with my girlfriend I decided to give Effexor another go as I was desperate to get out of this hole I had further dug for myself and I had become quite lethargic. I hadn't been this depressed before and Effexor certainly didn't have the same effectiveness as the first time I was on It. (this seems to happen when people have quit Effexor before)

Also I thought my levels of Serotonin were either too low or not having much effect due to a more pronounced depression and lack of sleep. Also, when I would take melatonin, I still couldn't sleep well, only briefly to wake up extremely foggy headed. A visit to a sun tan fixed this. I stopped using Melatonin with Effexor after that, but when I was off I tried again, with the same result: dull headed when waking up, tanning studio worked better than coffee.

So I started reading in to my meds and the first thing I discovered were articles regarding up-regulation of receptors and that long term Methylphenidate causes upregulation of dopamine receptors causing basic reward stimuli no longer being experienced as such but more or less only triggering fight or flight response resulting in fear and apathy in general, because one is no longer rewarded accordingly...

Could this percieved shortage or loss of effectiveness and longer discontinuation syndrome be caused by up-regulation by k-Opiod receptors?
These detect abnormally high levels of neurotransmitters and kind of make receptors less sesitive to protect the brain from posible toxic high levels. Down regulation on the other hand is painfully slow...Perhaps long term SNRI use also triggers adjustment in sensitivity?

More research seems being done now and it seems a more logical aproach to modify KOR instead of the underlying mechanism. From what I understand with the little knowledge of neurology I have gathered in the last few months SSRI's, SNRI's, and to an extent all medication that chronically create a surplus of a neurotransmitter will (with extended use?) cause the k-Opiod system to upregulate the relevant receptors, causing misery down the (longer) road.

Are there exeptions or has modern medicine been prodding away in our mysterious skulls once again, just to learn they almost got it but not quite?

For ones who like to experiment:
Sub perceptual micro-doses (2 dried leaves 0.5 gr) or if you like the effect a lager dose of Salvia Divinorum seem to have a long lasting antidepressent and anxiolytic effect (a few days to a week) due to k-opiod agonism.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2721268/

Anyway I stopped taking Concerta and Effexor and after a more prolonged and nasty withdrawl from the latter (brain zaps for 3 weeks tried suplementing with 5-htp at first (when off for a few days) with little effect, so after that didnt work, the next day and after that took 5 mg Citalopram when they got really annoying It has been 3.5 weeks now it used to last only a few days last time. But it seems my mind is almost back to normal and feel much better now and I look forward to experiencing some fun times again!

But finally back on topic:

How does Pyrazolam's withdrawl potential compare to Etizolam?

As I felt like crap today: lack of apetite, nausia, insomnia, just blegh.. You know.
But these symptoms could be very well related to the stuff mentioned above or does a general nasty wheezy stale feeling sound familiar? Would you say i'm having withdrawal of the soul shattering type or the 'you probably shouldn't take 3 or 4 in one go kid' kind? XD
I have been nibling a couple now an then (2mg at night to get some sleep) for the last 2 months maybe 50-60 intas in total although I am a bit surprised at the amount, I hardly munched a strip at a time.. All super responsive a few days on then a few days off etc.. I rarely If ever take more than 3 days in a row as I also have other things to take, do.

-How close to trouble am I walking Is there still hope for me?
-Do I need to get all drastic and taper or just take a few weeks off?

Update:
I brazenly took 1mg Etizolam around 04:00 and I felt slightly better, but not much.

I didn't want to take more as it might be better not to, and at some point one must go to sleep without the aid of mental lubricants.

(I mainly use them for sleeping and 1mg of Pyrazolam also did the job just fine probably even better as I woke up with a clear head, would switching up have aditional benefits regarding dependency/half life/side effects?)

I will probably stay awake and try to have a good early sleep tonight to get back into the groove.

Hell maybe I have some totally unrelated funky ailment and I'm posting for all the wrong reasons, but I think I already feel an improvement underway.


(If this was too much of topic. I apologize feel free to move when needed)
 
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I'm glad to hear you're getting it together. You obviously have more ssri exp than me,(I've only had citralopram and mirtazipine), and that effexor sounds scary as fuck! Brain zaps after missing one day....? Shit. I can miss my mirt for a week and feel fine. You seem to know your AD's; what exactly is the difference between ssri and snri?

Regarding pyraz WD's, I haven't a clue- I've only started them recently. You're on a very low dose, so that will play a major role (I gobble them like sweeties; I did 12 yesterday, the last of my stash). Some people are saying these new rc benzos are easier to come off and slower to form a tolerance than "traditional" benzos, but there's very little hard data. It's frustrating. You may possibly experience some rebound anxiety and reduced sleep quality? Anyway, it's very good you're on a low dose. I suggest you PM mydrugbuddy; he's tapering from rc benzo's, and knows his stuff.

Edit: Sorry, I just read that you're careful to cycle; very wise. I really wouldn't worry too much, I think you'll be fine. I'm also a bit worried: I've been using pyraz and etiz way too much, around 4-5 day's at a time, large doses. I've given my stash to somebody I trust, and will use phenibut to cope with rebound anxiety.
 
20mg Diazepam per day W/D WILL cause seizure !!!! Never read the full post but it will !! You need to get your hands on lowest doze of valium/librium possible that takes the cravings away then very slowly lower it at extremely tiny doses over a long period of time, sorry if this is already covered but after the shit I been through I always need to warn people that they WILL take seizures.
 
Thank you for your in-sight . I might stay away from trying anti-depressants for now. Going to try out St John's wort tomorrow. waiting a day longer as two days ago had 2.5mg Etizolam over 2 days. I can still feel its effects well into the next day. That's when the depression starts. It's pretty horrible. And now I'm feeling a bit of relief that the depression is almost over (hope it's not a mood swing?) But it felt like Tuesday blues to a T. I will not be taking Etizolam again. It makes me depressed. It's not withdrawal.

Etizolam would be so awesome if it wasn't for that.

I want to try Pyrazolam, will post my experiences if i ever do.
 
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I'm thinking of switching from Diazepam to just Pyrazolam, it works a million times better for me, Diazepam is only good in stupid doses, not sure how this would affect me going from a up to 200 hours half life to a 8 hour half life with no metabolites because I've had seizures one being deadly,

most people do the opposite to detox, I'm on a Detox just now but I think I'm just gna be honest with the Psychiatrist and tell him I've been using these and show him the chemical structure next to Alprazolam chemical structure (almost identical)

I'm currently at 30mgs of valium per day wich just does not work, I think the half life is far too long for me to feel the proper effects of it, and I MUCH prefer the clear headed, mood lifting, no sedation that Pyrazolam does , I do still get little cravings for the typical muscle relaxants Librium, Valium (amazing combination for me for the stomach nerves)

No idea what the doc would do if I told him about the Pyraz, he can't cut me off because I was put on the programme on leaving the hospital through the massive seizure I took, I don't believe you can get Alprazolam on the NHS, so no idea how he would react, playing with my head a bit actually thinking about it , to be honest or not to be honest.
 
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