I can't seem to find much information on this by googling, so I thought I'd ask around in here.
What are the effects of peptides that selectively target each of the opiate receptor subtypes? Ie, endomorphin/DAMGO which target mu, DPDPE/DSLET/etc which target delta, and various ones which target kappa.
I'm vaguely familiar with the notion that mu stimulation induces euphoria, but is mu responsible for all the euphoric effects of opiates? In theory could one get high off a dose of endomorphin, even though it's endogenous? Which opiating effects are delta and kappa agonism responsible for?
What are the effects of peptides that selectively target each of the opiate receptor subtypes? Ie, endomorphin/DAMGO which target mu, DPDPE/DSLET/etc which target delta, and various ones which target kappa.
I'm vaguely familiar with the notion that mu stimulation induces euphoria, but is mu responsible for all the euphoric effects of opiates? In theory could one get high off a dose of endomorphin, even though it's endogenous? Which opiating effects are delta and kappa agonism responsible for?