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Pills, tested, ecstacydata.orgd eaten countless times, NO ROLL.

VincentOnE

VincentOnE

Bluelighter
Joined
Sep 11, 2009
Messages
647
Location
NorCal EastBay hitmeup
Hi, so

I’m a long-time roller.
My girlfriend and I went through a night of 1 Gram of mephedone, (4-mmc)
2 0.5 Xannies,
And 1 Busperione pill.


Ate 3 of my pumas, that not only did everyone around me roll off of, but that I’ve been rolling off of for a long amount of time.
Pills were tested, ecstacydata.orged, and eaten countless times.

I even went through the trouble, of going to my molly guy, to get some molly,
Raegent tested (Instant fucking black marquis)
That someore NEW people rolled off of,
and neither of us did.
(We both took 200mgs of some very nicely-washed white molly)

Me, nor my girlfriend, ended up rolling.

WHAT THE FUCK!?

I figured that because I felt close to a roll with enough mephedrone earlier in the day (Body flush/ euphoria/ etc), that I couldn’t roll with the MDMA


Anywho, will this still cause (possible) neurotoxicity/ Tolerance?
Has the MDMA that I’ve eaten, still done it’s damage/ now, without a roll, should I still have to wait a while prior to eating another pill?

Hope not ;/
 
Heyy, I've always wondered this too! If you've eaten MDMA, but no roll, or at the least, a very minimum roll happens, is it still doing some kind of damage? How exactly do tolerances work?

Sorry to hear that though, must REALLY suck... :/
 
Not sure if sources to other drug forums are allowed, but this is where I found this clip of information.


http://www.drugs-forum.com/forum/showthread.php?p=720302
made an interesting find here
"see below for copied text"


got to fool that damn 50 Post rule ;-)

there is quite an interesting mechanism of action going on with the 5-HT1A receptors. It is theorized that some dopamine releasing Neurones are triggered by postsynaptic 5-HT1A receptors. Further can dopamine release be inhibited by a sustained high level of serotonin in the synapse (i guess that this is an autoreceptor response to the serotonin). To my understanding this concludes that SSRI induced global rise in serotonin availability lead to low dopamine concentrations in the brain. Consequences include Bruxism, Resstless Legs, insomnia, agitation... all well known side-effects of SSRI's. The 5-HT1A agonist Buspirone seems to alleviate these side-effects by activating dopamine release.

Another interesting thougt: Rolling on MDMA is impossible while on SSRI. There is almost no high exept anxiety, agitation, seedyness... Firstly one would suggest that this would be due to the lack of serotonin releasing which is blocked by SSRI Serotonin Transporter inhibition. Now, i think that the main reason for "not rolling" is not the lack of Serotonin (there should be plenty cause of the SSRI) but rather a complete lack of Dopamine release. Some experience reports did actually suggest, that Buspirone had the ability to "bring back the roll" whilst on MDMA-comedown. Makes sense.
Click to expand...

So was it the Busperione? Or the Xanax?
Is my body still going to build tolerance?
Since no Serotonin was released, will there be no (possible) neurotocticity/ stress on my 5ht receptors/ other damage that would've hapened if I DID roll?
 
You didn't roll because you take too much drugs man.
Try taking a break and coming back at another time. IME you plurlifer's tend to eat way too much MDMA. Take a break buddy.
As for taking meph earlier that day....I'm pretty sure that did have some effect on the roll..But I don't know for sure because that's not something that I take so I haven't really researched it.
 
NationOfThizzlam said:
You didn't roll because you take too much drugs man.
Try taking a break and coming back at another time. IME you plurlifer's tend to eat way too much MDMA. Take a break buddy.
As for taking meph earlier that day....I'm pretty sure that did have some effect on the roll..But I don't know for sure because that's not something that I take so I haven't really researched it.
Click to expand...



Just because 90% of the posts in ED are *OMGIeat10rollsadaywheredthemagicgo//I abusedmdmaihateitcuzimonssrisnow//imdepressedandmdmasuckslolololaol* kids,
doesn't mean I am.

Aside from spending hundreds of $$ on post/pre load supplements that MIGHT even SLIGHTLY help repair myself, I'm in AMAZING physical condition, and I wait anywhere from 3 weeks to 2 months roll. (usually on the later side).

In addition to the fact that my girlfriend, who smokes weed everyday, and has only rolled 2-3 times, didn't roll,

it would be much more of an EDUCATED guess, and not just a shitty assumption, to think that the Xanax or Busperione had an affect on our roll, rather than just assuming the inability to roll that night was because "I eat too many drugs" or that I'm "aplurlifer who consumes too much MDMA"
Get off your high horse, you're a drug user just like the rest of us.
 
I've NEVER been able to roll. I've taken 6 rolls in one night and felt nothing. Not bunk pills, either. My friends who are experienced rollers were having a BLAST off of 2 or 3 (they were blue dolphins). six in just under 5 hours and no good effects. I still get the side-effects (lock-jaw, freezing my ass off, partial impotence) with no euphoric (or even good) feelings whatsoever. Everyone else was rolling balls from the same product I used and I was hardly affected (certainly not in a good way, i did throw up about 30 mins after parachuting the 4th pill).

I've tried rolling 3 times in my life, first time ever 2.5 rolls. 2nd time 6 rolls, 3rd time 3. Not once did I roll, so I feel your pain. I also started a similar thread to this one because I am just as confused.
 
VincentOnE said:
Hi, so

I’m a long-time roller.
My girlfriend and I went through a night of 1 Gram of mephedone, (4-mmc)
2 0.5 Xannies,
And 1 Busperione pill.


Ate 3 of my pumas, that not only did everyone around me roll off of, but that I’ve been rolling off of for a long amount of time.
Pills were tested, ecstacydata.orged, and eaten countless times.

I even went through the trouble, of going to my molly guy, to get some molly,
Raegent tested (Instant fucking black marquis)
That someore NEW people rolled off of,
and neither of us did.
(We both took 200mgs of some very nicely-washed white molly)

Me, nor my girlfriend, ended up rolling.

WHAT THE FUCK!?

I figured that because I felt close to a roll with enough mephedrone earlier in the day (Body flush/ euphoria/ etc), that I couldn’t roll with the MDMA


Anywho, will this still cause (possible) neurotoxicity/ Tolerance?
Has the MDMA that I’ve eaten, still done it’s damage/ now, without a roll, should I still have to wait a while prior to eating another pill?

Hope not ;/
Click to expand...


Why are you taking xanax + all this other shit with supposedly good pills? Unless I am reading it incorrectly that is.

I just don't understand why you would try to combine these as they don't seem to go with each other well.

Just wait a few months and try again with nothing else.
 
if you took the benzos with your roll.. then that's my guess as to what killed it.

as far as the neurotoxicity goes: you took the drugs, they got metabolised... whether or not you felt any effects, it is still going to cause some cellular activity, and thus: yeah, it will do damage.
 
I honestly think the mephedrone earlier that day is the clear (and obvious) answer- though mephedrone appears to affect dopamine levels more than serotonin, we still no very little about RC's and what chemicals and mechanisms they affect in the brain, and to what level. Given that mephedrone is indistinguishable from MDMA for some, and certainly more energizing and "happy", it stands to reason that trying to use MDMA after using mephedrone hours earlier is not going to work.

IMO It's much better to space out your mephedrone usage as though it's MDMA- just because it doesn't leave you feeling like crap afterwards like MDMA, does not mean it isn't having a deeper physical affect that will catch up to you eventually. It's not as special if you make it something you do every night of your weekend, and tolerance will build eventually, among other affects.
 
So, I may have misinterpreted this post, but from what I can see, in a 12-24(?) hour period, you took:
-about half a gram of mephedrone
-some Xanax
-some busperione
-3 confirmed-quality pills
-200mg confirmed-quality molly

And you're complaining that you didn't roll?

Christ, dude. I know you're, like, careful about supplements and taking breaks between rolls and shit, but that kind of drug intake in one night still strikes me as profoundly unwise, and if that MDMA dosage is even CLOSE to your "routine" roll (even if they ARE spaced out 1-2 months apart) you're well on the way to a hell of a tolerance issue. I space out my rolls about as much as you do, it sounds, but I max out at 2 pills OR 150-200mg molly, not both, and DEFINITELY not combo'd with benzos(???) and other stimulants. I just ... why?

With that out of the way, I think it should've been pretty blatantly obvious that eating meph, Xanax, and busperione before dosing on MDMA was going to muddle the experience at best, and it clearly did even worse ... it canceled the roll out entirely. Busperione is a 5HT1A partial agonist, which means that your serotonin system had already gotten some chemical tickling when you ingested the MDMA. I'm not exactly a high-level pharmacologist, so I couldn't deduce the specifics, but who knows? Maybe all the receptors were full of busperione when the MDMA showed up in your brain and it never got to go to work. Maybe the MDMA did go into full effect and some other inhibitory response caused by the drug combo prevented the effects from being manifested consciously. Nobody (that I know of) even has a good enough idea of 4-MMC's pharmacological action to conclusively say just how it impacted the situation, either.

Basically, it seems patently obvious that you combo'd stimulants and anxiolytics BEFORE rolling (why anyone would take Xanax or busperione before eating MDMA is completely beyond me) that ended up totally inhibiting your roll. Is this a huge surprise? Or did you already know that and just wanted someone to give you the neurochemical play-by-play?
 
greenbicman said:
Why are you taking xanax + all this other shit with supposedly good pills? Unless I am reading it incorrectly that is.

I just don't understand why you would try to combine these as they don't seem to go with each other well.

Just wait a few months and try again with nothing else.
Click to expand...
Eh, Just had a nice little high day, and I guess the inebriation from the other chemicals caused me to want to roll (After a 2 or so month hiatus from MDMA)
Didn't know, until recently, that they didn't go well together.


Blazif07 said:
if you took the benzos with your roll.. then that's my guess as to what killed it.

as far as the neurotoxicity goes: you took the drugs, they got metabolised... whether or not you felt any effects, it is still going to cause some cellular activity, and thus: yeah, it will do damage.
Click to expand...
I thought that it was the dopamine getting into your 5-ht receptors that caused neurotocticity?


Bsiren said:
I honestly think the mephedrone earlier that day is the clear (and obvious) answer- though mephedrone appears to affect dopamine levels more than serotonin, we still no very little about RC's and what chemicals and mechanisms they affect in the brain, and to what level. Given that mephedrone is indistinguishable from MDMA for some, and certainly more energizing and "happy", it stands to reason that trying to use MDMA after using mephedrone hours earlier is not going to work.

IMO It's much better to space out your mephedrone usage as though it's MDMA- just because it doesn't leave you feeling like crap afterwards like MDMA, does not mean it isn't having a deeper physical affect that will catch up to you eventually. It's not as special if you make it something you do every night of your weekend, and tolerance will build eventually, among other affects.
Click to expand...

Aw,, I've heard the meowmeow was a great mix with the MDMA.
And yeah, Now that meowmeow has its UK ban, I haven't been able to obtain quality product, so that was kind of a last time thing for me.


Pans-Advocate said:
So, I may have misinterpreted this post, but from what I can see, in a 12-24(?) hour period, you took:
-about half a gram of mephedrone
-some Xanax
-some busperione
-3 confirmed-quality pills
-200mg confirmed-quality molly

And you're complaining that you didn't roll?

Christ, dude. I know you're, like, careful about supplements and taking breaks between rolls and shit, but that kind of drug intake in one night still strikes me as profoundly unwise, and if that MDMA dosage is even CLOSE to your "routine" roll (even if they ARE spaced out 1-2 months apart) you're well on the way to a hell of a tolerance issue. I space out my rolls about as much as you do, it sounds, but I max out at 2 pills OR 150-200mg molly, not both, and DEFINITELY not combo'd with benzos(???) and other stimulants. I just ... why?

With that out of the way, I think it should've been pretty blatantly obvious that eating meph, Xanax, and busperione before dosing on MDMA was going to muddle the experience at best, and it clearly did even worse ... it canceled the roll out entirely. Busperione is a 5HT1A partial agonist, which means that your serotonin system had already gotten some chemical tickling when you ingested the MDMA. I'm not exactly a high-level pharmacologist, so I couldn't deduce the specifics, but who knows? Maybe all the receptors were full of busperione when the MDMA showed up in your brain and it never got to go to work. Maybe the MDMA did go into full effect and some other inhibitory response caused by the drug combo prevented the effects from being manifested consciously. Nobody (that I know of) even has a good enough idea of 4-MMC's pharmacological action to conclusively say just how it impacted the situation, either.

Basically, it seems patently obvious that you combo'd stimulants and anxiolytics BEFORE rolling (why anyone would take Xanax or busperione before eating MDMA is completely beyond me) that ended up totally inhibiting your roll. Is this a huge surprise? Or did you already know that and just wanted someone to give you the neurochemical play-by-play?
Click to expand...

That's not my usual amount, I was just inebriated and fiending for a roll that wasn't happening.
I usually take 100-200 mg's

But thanks for the confirmation that I constantly keep hearing about benzos affecting the roll.
 
VincentOnE said:
Hi, so

I’m a long-time roller.
My girlfriend and I went through a night of 1 Gram of mephedone, (4-mmc)
2 0.5 Xannies,
And 1 Busperione pill.


Ate 3 of my pumas, that not only did everyone around me roll off of, but that I’ve been rolling off of for a long amount of time.
Pills were tested, ecstacydata.orged, and eaten countless times.

I even went through the trouble, of going to my molly guy, to get some molly,
Raegent tested (Instant fucking black marquis)
That someore NEW people rolled off of,
and neither of us did.
(We both took 200mgs of some very nicely-washed white molly)

Me, nor my girlfriend, ended up rolling.

WHAT THE FUCK!?

I figured that because I felt close to a roll with enough mephedrone earlier in the day (Body flush/ euphoria/ etc), that I couldn’t roll with the MDMA


Anywho, will this still cause (possible) neurotoxicity/ Tolerance?
Has the MDMA that I’ve eaten, still done it’s damage/ now, without a roll, should I still have to wait a while prior to eating another pill?

Hope not ;/
Click to expand...



Ecstacydata.org ratios are useless inless u know the mgs which we dont.
Mdma:1 means absolutly zero to strength, it could be 1 mg of mdma or 200 mgs.
 
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