• 🇳🇿 🇲🇲 🇯🇵 🇨🇳 🇦🇺 🇦🇶 🇮🇳
    Australian & Asian
    Drug Discussion


    Welcome Guest!
    Posting Rules Bluelight Rules
  • AADD Moderators: andyturbo

Pill poppers: feature on analgesia/pain/serotonin

aesops

Bluelighter
Joined
Sep 23, 2002
Messages
148
Location
australia
From the Guardian online:

Of course, most pharmaceutical research is sponsored by pharmaceutical companies, which are understandably reluctant to explore the negatives. But what research there is suggests that analgesics, when used frequently, chronically reduce levels of serotonin, and increase levels of pain-signalling molecules. Earlier this year, the New York Times reported that a German study had found that even a two-week course of Tylenol (an American brand of paracetamol) "causes a drop in serotonin-receptor density in rat brains", an effect that is reversed when the rats are taken off the painkillers. If you keep fooling your brain into not feeling pain, your body will eventually fight back and make you feel more pain. And then you'll want more painkillers; it's a vicious circle.

Full article here

The article raises all kinds of issues in a meandering "Good Weekend" kind of way...but I thought it would be of general interest to this forum. Has anyone heard of the link between analgesia and serotonin before? I know, I know always with the rat's brains.

I definitely exceed the 'arbitrary limits' that are mentioned. Usually I am trying to control my body temperature, not a headache. And at the first sign of a sniffle I start dosing with Pseudo-ephedrine. Someone I barely know at work made an off-hand remark, "You take way too many pills, mate". That got me thinking and he doesn't know the half of it.8)
 
Top