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🌟🌟 Social 🌟🌟 PD Social Thread 2022-2025 v. Year of the Phenethylamine

Delsyd said:
I hung out with him last Friday. He is happy and well. BL just isn’t fitting in to his life the way it has in the past with the things he has going on (music, hobbies, relationship etc).
He did mention he hasn’t had psychedelics in a long time.
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that's very good to hear. still he is missed around here and I really feel like PD really slowed down after him going on his break. not blaming him though, obviously he owes the site nothing and brought more to BL than one can expect from one individual. hope he will back at least occasionally though.
 
iom said:
The more I learn, the more I'm inclined to agree with this. Chronic stimulation of serotonin receptors may disrupt long-time-scale homeostasis (over weeks, months or even years) through epigenetic mechanisms which may be very difficult to reverse. The consequences are hardly understood for many widely prescribed/used drugs like SSRIs of various kinds, anti-psychotics, buspirone, CBD, etc. I'm even wary of microdosing psychedelics. We desperately need more serious research into these epigenetic mediated effects, which in the long-term may be more profound than the primary effects. Of course such research could inform better treatments including possible occasional (as opposed to chronic) use of drugs like psychedelics to nudge the homeostatic systems in the direction we want to elicit desired long-term changes with fewer risks. This is easier said than done of course.
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Interesting, but not very reassuring.
I've personally found that serotonergics cause me more and more comedowns, whether prescribed SSRIs or plants like St. John's wort or saffron extract. But I wonder if psychedelics might have a similar negative impact?

As for CBD, I thought the mechanism was still different (5-ht1a) but what you say makes me wonder...yet I rather feel a positive afterglow (unlike SSRIs) the day after taking it...but maybe that's because I use hemp flowers, which also contain a whole bunch of other cannabinoids, flavonoids and terpenes?

Now, this makes me wonder about kava, because even though it's not supposed to be an SSRI, it has an MAOI action I believe, and therefore must necessarily increase serotonin levels? What's your opinion ?
 
Great to hear from you! I think a lot of us are doing really well right now. I've been getting really into making music, and it's been bringing me a surprising amount of joy. The weirdest thing is, it's been nine months since I got back into it, and I've never touched an instrument while in a chemically altered state of consciousness. Soon, soon, I keep saying - but it hasn't happened yet. I just need to lock in my fundamentals a bit more before I feel like that will be a good use of my energy.
 
Hey all. I haven't been on here much lately as I've been going through some personal issues.

First, my shrink had his license suspended back in April and I can't find a single provider in my network to see me, so I've had to taper off of my 3 psych meds (Lexapro, Remeron & Ativan).

I've been self-medicating with alcohol & phenibut, which isn't great but better than living in a constant panic attack.

I was in the ER last week with a-fib. My BP was around 200/130 and my pulse was going haywire, fluctuating erratically up to 200 bpm. They have me on megadoses of a beta blocker (propranolol) and I have to go for a bunch of testing.

Other than that, things are just ducky!!! 🐤

Much Love,
Dreamflyer
 
Did some nitrous yesterday. It's really changed since that time something within told me that my ego/person "is a child" and "is a limit" and that "i am new", to great hilarity. It's a lot more low-key since that time, but still enjoyable.

To be fair i wasn't very quick on the inhales this time. Using a tank instead of the usual cartridges disrupted my habit and made me cautious.

I had a very good night's sleep, better than in months i think.
 
Just waiting for my 3-ho-pce + scale, should be here relatively soon...

Anyone wanna shoot the shit with me while I wait? Yall can add me on discord, username: vadsline
No worries if not or whatever LMAO im booored and on adderall
 
Does anybody know how well allylescaline compares to synthetic/plant mescaline? I've always wanted to try mescaline but getting the necessary plant material to have an experience is way too expensive for me, and I'm thinking of just ordering some allylescaline instead.
 
cycloprop said:
Does anybody know how well allylescaline compares to synthetic/plant mescaline? I've always wanted to try mescaline but getting the necessary plant material to have an experience is way too expensive for me, and I'm thinking of just ordering some allylescaline instead.
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I have not done mescaline, so can't compare, but I have taken allylescaline. While it isn't a bad time necessarily, I still very much would like to take mescaline. From everything I've heard, it's fairly similar, just toned down a lot. Don't expect a heavy head trip or crazy visuals. It is nice though.
 
deficiT said:
I have not done mescaline, so can't compare, but I have taken allylescaline. While it isn't a bad time necessarily, I still very much would like to take mescaline. From everything I've heard, it's fairly similar, just toned down a lot. Don't expect a heavy head trip or crazy visuals. It is nice though.
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Still worth a try I guess. I might just have to fully commit and grow a San Pedro cactus, but that might not be possible given the climate I live in.
 
cycloprop said:
Does anybody know how well allylescaline compares to synthetic/plant mescaline? I've always wanted to try mescaline but getting the necessary plant material to have an experience is way too expensive for me, and I'm thinking of just ordering some allylescaline instead.
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I wish I could answer that for you.. I've had mescaline in cactus a bunch and have allylescaline in the collection, but still haven't got around to trying it out.

Mescaline is great.

I think I remember people saying they liked methallylescaline (MAL) slightly more than AL but that both were very worthy. I'm sure that all depends on the individual and the trip too.
 
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