Admittedly, the only time I've taken mushrooms with a MAOi was a combination of DMT, mushrooms and b.cappi, but even that didn't 'feel' like plain oral DMT. But I'm not really saying this in a subjective way- objectively, you won't be able to convince me that mushrooms and a MAOi give rise to an oral DMT trip because its actually not physically possible. Of course, to the tripping mind, they will
feel similar in effect, but 4-Ho-DMT simply doesn't transform into DMT. Its a semantic argument really (and one we've had before) but I do feel that its misinformation albeit of a small and probably inconsequential kind. Its probably a good idea for me to emphasise the subjective nature of this idea and remind you that when tripping on a gutful of mushrooms and moclobemide, the conclusions that you may draw from your experience are possibly unreliable, especially when it comes to actually making a clear judgement of your own particular state of mind. I'm sure that both shroom- and ayahuasca feel similar, but physically and chemically, they are not, which makes a big difference. Similar to how heroin (diacetylmorphine) and plain morphine are chemically similar and heroin metabolises quickly into morphine, yet they are not the same drug in most major ways, subjectively and pharmacologically.
Ismene said:
I find it indistuingishable from mushrooms and moclobemide. So shoot me.
Well, the fact that you find it indistinguishable doesn't mean all that much. Indistuingishable doesn't mean 'the same'. Many people that have used ayahuasca and shroomahuasca say that the experience is very different.
BANG
Well, it's N,N-dimethyltryptamine and psilocin is 4-hydroxy-N,N-dimethyltryptamine. Doesn't sound that "totally different" does it?
Of course they are structurally related compounds, but in strict reality, they aren't the same, and in effect they aren't the same. I mean, 5-Meo-DMT is a DMT-like molecule but very different to n,n-DMT in effect. Same as bufotenine, 5-Ho-DMT, similar in structure to n,n,DMT and 4-Ho-DMT, but very different beyond that. Same as codeine (3-methylmorphine), heroin (diacetylmorphine) and morphine, virtually the same structure, and all metabolising into morphine, but different effects.
I know that I'm splitting hairs here, but its all true....

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Ismene said:
The best introduction to DMT comes from (surprise, surprise) DMT itself
Not necessarily. Oral DMT can produce some pretty ferocious nausea. I love oral DMT more than words can say but the nausea is enough to even put me off.
I meant smoking DMT; I should have specified that. I would agree though that oral DMT isn't the best introduction to DMT in general. As a side note, do you find ayahuasca/pharmahuasca to be very subjectively similar to smoked DMT?
I don't agree with this either willow, I've always found DMT incredibly friendly, probably the friendliest psychedelic of them all. The only "extreme physical effects" is some vomiting and nausea and I'm not sure what "very bizzare mental effects" you're referring to, it's a beautiful, breathtaking psychedelic experience.
I guess I'm comparing smoked DMT to oral, which are very different beasts. Smoked DMT is easily the friendliest psychedelic to me, phsically relaxing, producing a profound euphoric state with beautiful visuals and a welcoming mind-set, but oral feels more "violent", with a tendency towards rapid mood shifts and more confusion. Once again though, a subjective judgement only.
Curious: do you get much nausea from mushrooms and MAOi?