Opiate withdrawal-like symptoms from stopping methoxetamine last wk, or hypochondria?

[deckmunki]

This might sound like a really daft post, but since I stopped taking methoxetamine 8 days ago, after daily low dosing - up to 100mg per day - since the start of December, I've been feeling very rough.

I spent the first three days irritable and grumpy as hell, eating a LOT, sleeping a lot - typical symptoms of amphetamine withdrawal I guess, and I assumed it was due to the cessation of dopamine reuptake inhibition, maybe? (I'm no chemist, so I can only go on what Google says).

BUT, throughout all that, and in particular since day 4, I have had really bad aches and pains in my forearms, shoulders, and calves. Also, I constantly feel like I have a low-level dose of 'flu - general aches, throat feels itchy, etc.

Even more strangely, Mrs Deckmunki noticed that my pupils were noticeably more dilated than hers all the time since maybe day 2, although they're not now. My eyes are itchy and raw, and watering a bit, and I've been sneezing a LOT. I put this down to a bit of hayfever from grass pollen, although I don't normally get hayfever.

Edit: I also noticed that I *really* felt the cold, even though the weather's been no colder than two weeks ago when I was methoxied all the time, and I've woken up a couple of nights in a row with some rather nasty stomach/lower-intestinal cramps.

So... Is this just a case of rampant hypochondria, or could it be - as F&B said he noticed after a few days' use of MXE - a bit of opiate withdrawal, and I should take this as a lesson not to go so silly with methoxetamine in the future?

Lots of hypochondriac love,

Dm

 

[f1ct]

Sure as hell sounds like withdrawal symptoms. This really shouldn't be terribly surprising, with the structural similarity to ketamine, and ketamine's known affinity for opiod receptors, right?

correct me if i'm wrong.

 

[Roger&Me]

^AFAIK it has more to do with the presence of the methoxy group on the phenyl ring, which massively increases the compound's mu receptor affinity.

 

[deckmunki]

Thanks for your replies Roger&Me and f1ct. I don't honestly know what the structural differences between ket and mxe are thought to mean in vivo, so it's interesting to see how someone with chemistry knowledge thinks it will be different.