Cut the Seroquel down to strictly 25 mg for 1 week, then 12.5 mg for another week, and then go off. It depletes anyone of energy, and isn't a "good" drug by any means. As for the Zoloft, I'd advise cutting the dose down to 150 mg for now. I'd think that alone would make you feel better. Try taking melatonin for sleep even if it doesn't seem effective, just like 3 mg. Take lots of showers and baths, and throw in a cold shower every now and then. It is good for energy and the body aches. Magnesium is good, too, for sleep, body ahces, anxiety. Try to "take it easy", go slow if you need to, do more if you want. Alcohol use is fine, as long as it isn't excessive, in fact for the body aches in particular I would suggest a drink or two, only when quite bad. Use ibuprofen/naproxen/aspirin as well for the aches. Perhaps try yoga, very good for stress and tension. Just a few ideas, here, but really get off that Seroquel. If all of this is employed, the anxiety should fade, though it could be rather slowly, and a sense of well-being should be restored.