• N&PD Moderators: Skorpio

Neurochemical Explanation of the Anxiogenic Effects of THC/Cannabis

oh ive read something about that, it was about how THC inhibited GABA neurotransmission. for what i know, CB receptors are pre-synaptic receptors that when activated prevent the release of neurotransmitters such as GABA for example.

i don't remember the term, i guess it was 'cannabinoid induced suppression of inhibition', google it
 
oh ive read something about that, it was about how THC inhibited GABA neurotransmission. for what i know, CB receptors are pre-synaptic receptors that when activated prevent the release of neurotransmitters such as GABA for example.

i don't remember the term, i guess it was 'cannabinoid induced suppression of inhibition', google it

I was literally just on the shitter when the thought that it had something to do with GABA came to mind; then I read this post. Thanks for the info.
 
I don't know if anecdotal evidence is accepted, but cannabinoids aren't uniformly anxiogenic in everyone.

Most certainly, I can agree with that. However, especially in higher doses or those with no tolerance (see oral consumption - especially in novices), we see a consistent increase in paranoid, schizo-type effects. "Every move of mine is being scrutinized."
 
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