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NBOMe snog, marry or avoid?

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Havent tried any yet personally, so I can't offer anything useful, but perhaps I could piggy-back another NBOMe question on your thread?

Which of the NBOMe's is most like it's parent 2c-xx original? Is 25c for instance more similar to 2c-c than 25b is similar to 2c-b?

etc etc
 
I personally haven't had a tinker myself but I have had experience with a variety of psychs old skool and new.
I have a chance to have a go later. I have done lots of reading but am still undecided on which to try.
For example I would snog LCD,marry 2CI and avoid DOI.
Think I may fancy a snog tonight. Its been a while ;-)
 
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I wouldn't marry any of them, as the tolerance NBOMes induce means you can only be intimate with them (or any other chemical trollop) once every week or two. So I suppose I'd er, snog, 25C.

Which of the NBOMe's is most like it's parent 2c-xx original? Is 25c for instance more similar to 2c-c than 25b is similar to 2c-b?
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None of them are so far as I can tell, really, nor should they be expected to be. Here's my copy/pasted speculative explanation from a previous post as to why:

IIRC the reason NBOMes are so much more potent than their 2C-X counterparts is because the portion of the 2C-X molecule within the NBOMe structure that actually docks with receptors ("functional group," I believe) on neurons juts out into space more than it does in the 2C-X structure, making it more accessible. This alteration in how the molecule interacts with receptors is pretty dramatic it terms of potency increase, and so I'd think it would also dramatically change other properties of the molecule that relate to producing qualitative effects. This qualitative change with 25-Xs could partially owe, for example, to a change in the pattern of "spreading activation" of neural networks, perhaps by causing individual neurons to fire at a higher or lower frequency than their less potent 2C-X counterparts. Even a slight change at the local neuronal level could snowball into dramatically different network activity patterns, and so there goes any consistency we might expect to find between the actions of 25-Xs and 2C-Xs in the brain.
 
I love 25c I do, but she is too jelly, one go with her and I hope you had your fun for the next two three weeks all the other girls will be too scared to be seen with you.
 
You mean because of tolerance? It doesn't bother me. My days of tripping more than one every 2 or 3 weeks are behind me.
 
psood0nym said:
None of them are so far as I can tell, really, nor should they be expected to be. Here's my copy/pasted speculative explanation from a previous post as to why:

IIRC the reason NBOMes are so much more potent than their 2C-X counterparts is because the portion of the 2C-X molecule within the NBOMe structure that actually docks with receptors ("functional group," I believe) on neurons juts out into space more than it does in the 2C-X structure, making it more accessible. This alteration in how the molecule interacts with receptors is pretty dramatic it terms of potency increase, and so I'd think it would also dramatically change other properties of the molecule that relate to producing qualitative effects. This qualitative change with 25-Xs could partially owe, for example, to a change in the pattern of "spreading activation" of neural networks, perhaps by causing individual neurons to fire at a higher or lower frequency than their less potent 2C-X counterparts. Even a slight change at the local neuronal level could snowball into dramatically different network activity patterns, and so there goes any consistency we might expect to find between the actions of 25-Xs and 2C-Xs in the brain.
Click to expand...

My question nicely dealt with, cheers :) Perhaps I should rephrase my question but I'll save it for a thread of my own :) Please excuse the hi-jack.
 
I would avoid 25i too. I would have a casual affair with 25n though - nothing serious, mainly for the novelty.
 
Si Ingwe said:
Havent tried any yet personally, so I can't offer anything useful, but perhaps I could piggy-back another NBOMe question on your thread?

Which of the NBOMe's is most like it's parent 2c-xx original? Is 25c for instance more similar to 2c-c than 25b is similar to 2c-b?

etc etc
Click to expand...

This question is dealt with in this thread

About the rest of this thread:

For the time being it is shut down because simply recommending for or against NBOMe compounds is not in the spirit of our "what should I take?" rule. Please visit the Big & Dandy threads for each of these compounds and make up your own mind, or if you must: use the search engine to hunt down the comparison threads. I'm sorry but this one is just cutting way too many corners.

If you want your drug discussion more off the bat and cozy I suggest you check the social forum for your area.

You are welcome to message me and state your case if there is a clearly formulated question about NBOMe compounds you wish to discuss, though you can always create a new thread for that.
 
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