Opioids MS Contin & Forgetfulness

[motherofearth]

Hello OD, I used the search engine looking for anything on this matter and didn't return w/ results, so I hope this isn't superfluous. If this needs to be merged somewhere, please do mods.

Currently, my DOC is ms contin - 300mgs several times a week. I've most recently, and throughout this year, struggled to kick heroin, cocaine, and meth addictions. This month I've succeeded in not doing any of these drugs, however, I still occasionally indulge in ms contin.

My question is specifically for those who use ms contin in any capacity. For those who do: do you feel any negative effects on your memory? I read a post in another thread identifying morphine as the worst opioid on memory. It could be simply an after-effect, a fog, which comes on the following days, b/c I'm noticeably less acute in my thinking/recall for 5 days following my typical dose. After that I feel a little more clear.

In any case, I've always gravitated towards opiates and rationalized my use by the lack of severe repercussions it inflicts upon cognitive faculties and recall. Am I mistaken in this notion? Or are opiates, morphine in particular, only relatively soft on the brain?

Any information/experience regarding ms contin use is appreciated.

 

[morphonorconic]

Congratulations on your success in quitting the aforementioned substances

MScontin absolutely leaves me in a foggy state for at least a day or two after dosing, especially at 200-300mg+. And despite crushing/chewing it up completely, it would still last forever.

Definitive research reports/studies and information available on the relationship between opioids and cognition is limited, often simply anecdotal, and even more often is tenuous and contradictory. Simple answer though: Opioids, morphine included, are not neurotoxic. Therefore, there is no (known) direct mechanism of action which adversely affects cognition.

 

[motherofearth]

Definitive research reports/studies and information available on the relationship between opioids and cognition is limited, often simply anecdotal, and even more often is tenuous and contradictory. Simple answer though: Opioids, morphine included, are not neurotoxic. Therefore, there is no (known) direct mechanism of action which adversely affects cognition.

Thank you for your response. Ostensibly, the portion of your reply above is what I've read in the past on opiate use and the brain. Yet I wanted to be sure I wasn't doing untold damage unknowingly, or if anyone had a similar experience. You're probably right in mentioning the ER as a contributing factor. Speaking of which, chewing up the pills and/or removing the coating does nothing to neutralize the time release; that mechanism is tied to the wax matrix within the accident of the pill itself. However, a mod on this forum, tricomb, claims it can be circumvented by dissolving the pills in cool water and allowing them to sit for 8-12 hours. This essentially uses time to defeat the ER function.

 

[morphonorconic]

^Crushing ER morphine does not "defeat" the time-release, no, but it certainly compromises it. It allows for increased surface area exposed to metabolic processes, but it's true the active compound morphine sulfate is still sequestered within the wax matrix, even when physically pulverized prior to consumption. Instead of taking one 100mg ER tablet, it's more like taking 100 1mg ER tablets.

Never tried the cool water disolution method, but it sounds plausible.

 

[OpiumKing]

Let me add my two cents to help you out a bit. Taking most opiates slows down your respiratory system there by reducing oxygen levels in your brain. This is what is causing your memory loss. There have been studies on this so look it up if need be. Anyway what I have been doing to help this problem is taking a mild stimulant with my ms contin to up my oxygen levels in my brain. I can tell a big difference when I do this with recall & memory. Any stim will do ..even sudafed. Hope this helps you out. Cheers M8