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Mental Health Mirtazapine and possible (safe) prescribed combinations

mydrugbuddy

mydrugbuddy

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So ive just done 12 years on sertraline and it seemed to have "pooped out" on me by the end, so ive switched to Mirtazapine about 5 weeks ago. Im on 30mg. Ive noticed it makes me feel calmer and much less anxious than i was on Sertraline but it (Mirtazapine) doesnt seem to be doing anything for my depression.

Has anyone else found themselves in a simillar position regarding Mirtazapine ?

I hear its possible and safe to combine it with other meds such as venlafaxine.

Has anyone tried any Mirt' combinations, and did they ever find anything that succesfully improved the way they felt ?

EDIT: I've just read that Wellbutrin combines well with Mirt'. Going to see the doc about this ASAP.

Anyone here tried that combo ?
 
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I'm having remarkable, glorious, life-saving results from Mirtazapine 30mg and desvenlafaxine (Pristiq) 50mg. I would have gone with Effexor but it isn't nearly as powerful an NE reuptake inhibitor as Pristiq until you get into the higher doses, which means titration and time which I didn't have to spare. I had attempted suicide a number of times in a year and was in a coma twice. This combo has me feeling better than well.
 
I take 30mg of mirtazipine, but only at night as a sleepaid. (Ive gained a lot of weight!) When i took it with amitrptaline i felt extremely calm, but it could be risky to mix them.

Shit sorry i reposted twice; how do i delete posts?
 
I can tell that Mirtazapine isnt going to work on its own. Im just concerned that if i go back to the doctor after 6 weeks on it, and tell her this, she will just say that ineed to give it a bit longer.

From what Ive read, Wellbutrin could be the ticket. If she wont give me a prescription I'll just have to get it myself off the net. :(

Im putting on shit loads of fat around my belly too. I wake up around 3 or 4 times a night craving food. At least my mental health intervention worker has suggested i try grapes or strawberries or something instead of packet upon packet of chocolate bar. I'm doing that, but I'll ravenously wolf down a whole carton of grapes which sees me through one or two of the mid - night wake ups, and using chocolatey breakfast cereal for the others.

Im supposed to be using bupe to taper off opiates, but just end up taking more and more until eventually i feel ok. Everything is going in the wrong direction.
 
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They really give you the munchies bad, don't they? The thing with these types of drugs is they're not gonna make you feel on top of the world; they're subtle like that-you'll still have bad days, you'll still get the blues sometimes. If your still feeling absolute, rock-bottom, can't even move, wanna kill myself clinical depression, I've personaly found these very effective for that, but yeah I do still have bad days, and it doesn't mean they're not working. I know everybody say's it but you really do need to give them time....

Btw it took 2 and a half months untill I noticed a difference. Don't be in a rush to commit to taking more medications than you need, it's an easy trap to fall into.....
 
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I've just upped my dosage from 15mg mirt to 30mg.

For me it was a life saver. Without it I probably would be dead.

Last week (about a week after upping my dose to 30mg) I actually felt the emotion of happiness for the first time in a year. I was actually feeling quite good. Sadly, this week I have been quite down, particularly today. I'm hoping it will have some decent effect over the next few weeks. Although, I felt a bit manic whilst I was feeling good. Now it just feels 'pooped out' as you put it.

But yeah, in terms of lasting side effects all I have noticed is weight gain. I've put on probably about 10kg. But then again I lost 10kg due to depression/anxiety - so I guess I am back where I started.

I can concentrate a lot better than I could. I sleep well. It has done more for depression than anxiety. The intense hunger faded after two weeks I haven't noticed it during my dosage increase.

Sadly, I can't comment on how it is with other meds.
 
Your 30mg dose is also working for me perfectly, I've not been depressed for years. The intense appetite can be a bitch, though. I'm doing great on my diet, eating just 1 meal a a day, then the mirt kicks in, and I'm raiding the fridge...I wonder if they give this to people with eating disorders?

Mydrugbuddy: are you noticing any positive improvements yet?
 
I think my problem with Bupe is affecting everything else. Ive been taking it in a happy go lucky way for a couple of months, and am paying the price now. Literally as well as metaphorically. I've decided that cannot carry on, so have cut right down, to 4mg, or it might be 2mg cos some of the tablets dont seem to do anything. So with minor Bupe withdrawals to deal with it's hard to say what the Mirt is doing, but Im gonna keep on taking it, like you say my mood isnt dropping too low, so maybe the Mirt' is helping.
 
Yeah, obviously bupe withdrawals are going to make noticing any tangible improvements quite difficult to really notice. (The good thing with coming off bupe is there's no black depression you get with coming off heroin, although the detox process is longer). The fact your mood isn't too low is a very good sign the mirt may be working for you. As I said earlier, ssris aren't "happy pills" as I've heard them described- I'd call them "normal pills". Have you tried taking them before bed as a sleep aid by the way? (This is how I use them).

I think I read in another one of your posts that you're coming off RC benzo's (sorry if I'm mistaken). If so, how is that working out for you?

Edit: have you tried using loperamide or kratom for your WD's; it's something I'm considering these.
 
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I have been through the a - z of drugs - spent the last 4 years on nardil which was wonderfully effective but horrific for side effects.

I came to realise that much of my anxiety was obsessional so I tried the most effective drug for OCD - Clomipramine.

Currently on 100mg at night. No weight gain (actually have lost a bunch of weight and bulked up at the gym) no cognitive side effects, it is really easy to live with and I am feeling great!
Not perfect but pretty damn good - good enough.

A dry mouth overnight is about the only hassle - very much worth a try - it is dirt cheap too
 
It's funny you should mention obsessive behaviour...I've had the "conventional" ocd's cleanliness compulsion etc but when I think about it, my urge to use drugs is obsessional. I could feel fine, but convince myself I feel terrible unless I use something. Eg: I've given in, and taken etiz for the fith night. I'm very worried about addiction but I just get this unbearable compulsion. Do you think the drug^ you described work for this, or is it just part of life as an addict?
 
I'm taking 300mg of venlafaxine in the morning and 45mg of Mitrazapine at night. I was up to 60mg of Mitrazapine but have dropped it back. I went to my doctor with a heap of information on combining the 2 and he was happy to give it a go although I needed weekly ECG's for the first few months because it can do weird things to your heart rhythm. I love the combination and it stopped my anxiety in it's tracks. I still take diazipam as required but I hardly ever need it now. I had been taking Methadone for the last few days as I injured my neck (was getting it from a friend) but my doc said that's a really bad idea as It could potentially cause Serotonin Syndrome however he put me on high doses of codine which can do the same thing and doesn't work anywhere near as good for the pain.
 
dopemegently said:
It's funny you should mention obsessive behaviour...I've had the "conventional" ocd's cleanliness compulsion etc but when I think about it, my urge to use drugs is obsessional. I could feel fine, but convince myself I feel terrible unless I use something. Eg: I've given in, and taken etiz for the fith night. I'm very worried about addiction but I just get this unbearable compulsion. Do you think the drug^ you described work for this, or is it just part of life as an addict?
Click to expand...

Check out http://en.wikipedia.org/wiki/Primarily_Obsessional_OCD

It helped me
 
A combination of Mirtazapine and Desvenlafaxine pulled me out of a bottomless, suicidal depression. They are extremely synergistic, one being a Serotonin Norepinephrine Reuptake Inhibitor and the other a Norepinephrine and Serotonin Specific Antidepressant. Google "California Rocket Fuel." I HIGHLY suggest this combo.
 
after several weeks the mirt seems to be working and the munchies side effect thing has gone. I do take modafinil with it aswell though, thats becoming a habit now too, done a couple of weeks straight on it, gonna have to give that a break soon and see how i feel on just the mirt and the 0.5mg of bupe im now down to.
 
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