Thanks for your input, Ralt, much appreciated. Do you have tolerance to methoxetamine or cross-tolerance to ketamine or any other NMDA-antagonists?
i iv it, but it's strong and lasts long and its easy to black out and do crazy PCP like things. so be careful.
plus if ur like me and keep redosing, u build a tolerance quickly and then ruin ketamine bc of cross tolerance
No one has separated the isomers to my knowledge, 'tis no easy task (comparatively) and if someone had many people would be very excited to hear the results. So, you've go to ask yourself, which is more likely, that you received a hitherto unknown product (S or R MXE) or else your vendor just sent you some shite?
(rhetorical question)
There are tw stereoisomers of mxe, r and s (or dextro and levo). generally speaking unless you use reagents that are present in an enantiomerically pure form, youll end up with exactly 50% r and 50% s isomer. while separating them usually isnt very difficult (e.g. with s/r tartaric acid), i havent heard it to be done with mxe which makes it very unlikely (it creates additional costs for no benefit of which i know).Im really not very knowledgable on this kinda thing, but I guess what I was thinking, was that the isomers were not intentionally separated at some point, but that somehow in the synth, there got to be moreso of "this" isomer ,as opposed to "that" isomer. I would imagine this is possible
There are tw stereoisomers of mxe, r and s (or dextro and levo). generally speaking unless you use reagents that are present in an enantiomerically pure form, youll end up with exactly 50% r and 50% s isomer. while separating them usually isnt very difficult (e.g. with s/r tartaric acid), i havent heard it to be done with mxe which makes it very unlikely (it creates additional costs for no benefit of which i know).
I never really liked MXE because it didn't get me very far out there at reasonable dosages and is far too stimulating. I like to pass right out after a dissociative experience. Anyway, I gave it another chance yesterday after not having touched it for 18 months, this time IV. I have no tolerance at all.
Tried 80mg IV and when I was still able to move around just fine I threw another 30mg rectal into the mix within a minute. I honestly can't say I didn't enjoy it, eventhough I'd go for 100-110mg next time. Main effects were ~90min, pronounced dissociation for another 3 hours, sleep would've been possible at around 7h I'd say.
Unfortunately, it did nothing in respect to battling my current depression. Today I am experiencing a pretty bad headache and am feeling quite lethargic. :/
I did read it to make sure, but think you misunderstood that article. It IS possible to separate a racemate, but for the synthesis to yield anything other than an equal amount of each stereoisomer you need to have a "chiral influence" in the reaction. Read the synthesis section.you can end up with different ratios besides 50 50 if you do recyrstalizations
http://en.wikipedia.org/wiki/Racemic_mixture#Crystallization
read the section of crystallization, talkes about how you get ratios of enantiomers other than 50 50 from a crystalization, depending on what salts are being formed, so the possibility exists without complex techs such as chiral chromatography or chiral resolutions.
don't know what the behavior of mxe is....anyone know the anser to this question, how do the r and s enantiomers of mxe crystalize under various conditions?
r
I did read it to make sure, but think you misunderstood that article. It IS possible to separate a racemate, but for the synthesis to yield anything other than an equal amount of each stereoisomer you need to have a "chiral influence" in the reaction. Read the synthesis section.![]()
the point i'm trying to make to you is that with certain compounds...when you do a recrystalization of the racimate, you can selectivley crystalize out only one of the enantiomers, or in other cases a mixture crystalizes out that is NOT 50/50. Also, there are very cheap optically pure compounds such as tartrates that can be used to make tartrate salts for example and selectively crystalize out a single enantiomer (or enantioenriched crystal)
That's what I said originally. I am fully aware that it's often quite cheap and easy with d/l tartaric acid.[...]while separating them usually isnt very difficult (e.g. with s/r tartaric acid), i havent heard it to be done with mxe which makes it very unlikely (it creates additional costs for no benefit of which i know).