I've been wondering a lot lately about the fact that methadone acts not only on the opioid receptors, but also "binds to the glutamatergic NMDA (N-methyl-D-aspartate) receptor, and thus acts as a receptor antagonist against glutamate." (Wikipedia). Does this mean that methadone is also a dissociative, like DXM or Ketamine? I'm on MMT, and I've noticed that sometimes I can feel a dissociative effect in the first couple of hours.
If it is, I wonder what sort of long-term psychological effects this can have on long-term use, compared to that of a traditional opiate. On the few occasions that I attempted cold-turkey withdrawal, my mind felt like it had been in a coma for years and just woke up; I am not referring to the extreme emotions that one experiences during withdrawal, but rather suddenly becoming aware that I was emotionally numb during use.
Your thoughts?
If it is, I wonder what sort of long-term psychological effects this can have on long-term use, compared to that of a traditional opiate. On the few occasions that I attempted cold-turkey withdrawal, my mind felt like it had been in a coma for years and just woke up; I am not referring to the extreme emotions that one experiences during withdrawal, but rather suddenly becoming aware that I was emotionally numb during use.
Your thoughts?