Tryptamines Mescaline hcl microdosing schedule and dosing?

[Coffeeshroom]

Okay so I got my hand on some Mescaline hcl to use for microdosing.

The reason is to lower my daily methadone and benzos use to the lowest point possible and then from there swap over to other stuff I want to microdose and use in the getting clean or completely off it.

I have done a few not a lot but most research that I could get ahold off and this is what I have come up with. Questions or 4 points I have so far

1. Microdosing dose should be 5-10% of the therapeutic/dose that will give full effects, dose 200-400mg of Mescaline sulphate which converts from research to 178-356mg Mescaline hcl.
Seeing as I have Mescaline hcl, at minimum 8.5mg to 17mg..
So going with a 5-10% dose, that will be 8.5 - 17mg Mescaline hcl microdosing.

2. Is the dosing schedule.
So far I have found 2 days on 2 days off
5 days on and 2 days off.
2 days on 5 days off. In other words alot of different schedules or ways to approach it but I think I'm gonna lean towards the half life of the drug and with that I was thinking dosing eod.

3. Time frame. A minimum of 4 weeks and max of 8 weeks, guess all dependent on the substance used for this. So was thinking 6-8 weeks depending on how I do the dosing.

4. My dosing. Seeing as my 5-10% dose will be between 8.5mg-17mg if I'm correct. So day 1 start with 5 drops and increase 1 drop eod till I get to 17mg.

So with all said and typed any info or pointers, help, input, warnings and etc would be gratefully appreciated.

From the 4 points I made I would like to know if I'm correct in my calculations on dosing and dosing regime. So any input to any of the points would be gratefully appreciated.

@Shinji Ikari I know you have microdosed Mescaline, what was your dose and regime and so all if you don't mind me asking.

Sidenote after this I want to then turn over to blue and pink lotus with sceletium. Hoping to use that in the period when I want to get off the methadone.

So wanna use the Mescaline microdosing to lower my methadone usage to low as possible in the 40 days roughly I will be using it, though I can make it 60 days, I think. Still need to do some calculations And then after that use the lotus and sceletium in the full wd phase, also will have benzo and gabapentinoids as comfort meds but wanna try do this without them if possible. but that is a convo for later, for now it's just the microdosing of the Mescaline and if I'm on the right path.

Then also I'm still looking for a natural alt for mood stimulation and energy as just sativas is not gonna cover it purely for get up and go motivation and energy in those lethargic days.

My plans so far. I have already stocked up on 400mg Mescaline hcl. In a dropper bottle. 1ml = 13.3mg Mescaline hcl. Have 4 different strains of RSO for the off days. Off days I'm thinking of dosing 0.1ml of RSO which = 75mg thc and days off half the dose, so 0.05ml RSO = 37.5mg thc.

I got the following RSO strains 1ml of each except 2 of the Chocolate Haze
Chocolate Haze - Sativa ( currently using, mornings only 0.05ml )
Watermelon Zkittlez - Hybrid Indica dominant
Tart pops + slurricane - hybrid indica dominant
Gelonade - hybrid sativa dominant

I also got Moringa Oleifera as a support supplement too. 500mg 3x a day.

So that's the idea. So with what I have research so far am I on the right path.

Any input and advance would be very much appreciated.

Awe
Coffeeshroom

 

[Didgital]

dose 200-400mg of Mescaline sulphate

This is already more complicated than you need. If you have the HCL, why are you even looking at the sulfate potency, which just an FYI mescaline sulfate is almost always a mixture of mescaline monosulfate and mescaline hemisulfate, so dosage regarding sulfate really depends on the material and the pH at which it was salted.

You have the HCL which exists as a single molecule of mescaline to a single molecule of hydrochloric acid so there is no confusion.
Average dose of the HCL lets say 330mg. 330 x 5-10= 17-33mg.

17mg I would personally consider a complete waste of good material but that's just my opinion. Maybe, 33mg would have a noticeable effect, but if I was going to microdose mescaline I would probably aim for like 50mg. Again that's just me. Everyone is different and has to find their specific "microdose". Even 100mg I would find it very light.

Mescaline is kind of a strange substance IMO, in that it really takes me quite a lot to even begin to feel it, and then if I push dosage, the intensity becomes almost overwhelming. I believe my highest dose of the HCL was 666mg (lol I had 2x doses of 333mg that no one wanted to share w me so I took them both) I quit smoking tobacco that night for several years.

 

[Shinji Ikari]

I think I was dosing something like 40mg of HCl a day for a couple of weeks. I wrote it all down somewhere... I'll have a look tomorrow.

Tempted to revisit this, but mescaline is rare here and I only have a couple of grams (or less) on hand.

 

[Coffeeshroom]

I think I was dosing something like 40mg of HCl a day for a couple of weeks. I wrote it all down somewhere... I'll have a look tomorrow.

Tempted to revisit this, but mescaline is rare here and I only have a couple of grams (or less) on hand.

Please do. Did you dose every day or take breaks, and guess i have to up my dose I can get another bottle or 2 of it, just bloody expensive for the hcl dropper concentrate. also my tolerance to psychedelics is low or is that not gonna matter here.

There is also a powder version that is a lot cheaper and comes in 5-10g batches. Will this be the suphate version of it @Didgital

 

[Esperighanto]

I think I was dosing something like 40mg of HCl a day for a couple of weeks. I wrote it all down somewhere... I'll have a look tomorrow.

Tempted to revisit this, but mescaline is rare here and I only have a couple of grams (or less) on hand.

Assuming you can access Trichocereus cacti (they're sold at Home Depot and Lowe's here in the USA) you can just use vinegar and orange oil to extract mescaline acetate. I'm intending on trying to acquire a few hundred pounds of raw cactus to extract in a bathtub style to build a supply of mescaline that will hopefully last me a few years. It's trivial to grow fungi at that scale, but acquiring harmaline or mescaline at that rate is much trickier. Things that require synthesis as opposed to extraction I'm excluding from this pattern of thought.

Sorry if a bit goofy, just smoked amanita for the first time and it's nice.

 

[iom]

I think 40 mg sounds about right for a minimal effect for most people. I don't really believe in microdosing, if for no other reason than there is absolutely no consistency whatsoever regarding recommendations I've seen. I'm also skeptical that sub-threshold doses even do much of anything. I assume that you either you take enough to feel it or you don't benefit. I do however think that semi-frequent "mini dosing", in which the aim is to achieve a minimal effect and no more, may be beneficial.

I would not take a psychedelic daily, and would not take them on two days in a row excepting occasional special circumstances like festivals or retreats. If one wishes to take minimal doses repeatedly, I suggest a dose frequency of once every 5-7 days and no more than once every 3 days. This is my suggestion in general, but I'm not at all familiar with microdosing as a strategy to ease symptoms of withdraw from other drugs. The thing is, it tends to be very difficult and not desirable to maintain primary psychedelic activity all the time (even at a minimal level). Fortunately, many beneficial effects of psychedelics overall last well beyond the primary effects, and if these post-trip effects help alleviate withdraw symptoms then one can probably get good results with the once every 5-7 days frequency I suggest above.

One other thing I'd say is that I think the post-trip effects get a lot better if one can increase the trip dose, but of course that means experiencing stronger effects. OTOH, the post-trip effects also last longer with bigger doses, so one can and probably should dose a bit less frequently. As such, the best dose likely depends on what one can physically and psychologically tolerate. I would definitely be wary about taking too much if in the midst of benzo withdraw. It's probably good to start at 40 mg or maybe even 20 mg to be sure you don't have any issues.

Whatever you choose, I hope it works out for you. Mescaline (in cacti) has always been a very special ally to me.