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Mass Spec. Of DOI HCl

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raybeez

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A supplier of DOI HCl has provided HPLC and Mass Spec data for their product.

The MS shows a major peak at m/z=322.0, which I guess is supposed to correspond with the DOI Freebase FW=321.15.

However, two other noticable peaks (both equal to ~10% the height of the major peak) are present. One comes in at 323.0, the other comes in at 305.0. I can come up with a few explinations for the 323 peak (i.e. protonation at the amine group), but can't figure out what the 305.0 peak would correspond to.

I'm pretty rusty at this; would it just have something to do with how the molecule fragments? Any help would be appreciated!!

p.s.

The HPLC data shows readings given at three different wavelengths. Two of the three wavelengths show a nice, single clean peak at around 5min.45sec. The third shows the same peak, as well as a broad dublet peak coming off between 1min15sec and 2min. Both parts of the dublet spike about 80% as high as the 5:45 peak. More info on the run conditions can be provided upon request.

Thanks!
 
Mass of DOI is 321 (there are only full numbers!) ,you see an ion (Mass+H) = 322.The 323 is from C13 (the natural carbon isotope occuring 1.1%).

The phenethylamines always show a fragment ion M+H minus 17/Ammonia (=305 here).

As for the HPLC,whats the wavelength of "unpure" spectra?I guess the broad dublet is from the solvent,2min though is a bit "late".You could PM me a pdf as I have several reference spectras.
 
hugo24 said:
As for the HPLC,whats the wavelength of "unpure" spectra?I guess the broad dublet is from the solvent,2min though is a bit "late".You could PM me a pdf as I have several reference spectras.
Click to expand...

The wavelength was 215.8nm. Thanks for the help; watch for my PM.
 
This is a very pure batch.I suspect one might judge this as more potent as the earlier shitty batches.Careful you of those taking high doses,every batch has to be reassayed!!!
 
hugo24 said:
This is a very pure batch.I suspect one might judge this as more potent as the earlier shitty batches.Careful you of those taking high doses,every batch has to be reassayed!!!
Click to expand...

Thanks for looking into this.
 
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