If the reagent turns bright orange within 20 seconds, this indicates the presence of a speed-like substance (amphetamine or methamphetamine). Proceed to Step #2 (Simon's reagent) to determine which speed-like substance the pill contains.
If the reagent turns black with a possible dark purplish or bluish tint, then it contains either an ecstasy-like substance (MDMA, MDA or MDE), or the cough suppressant DXM.
The DXM reaction is typically slower, with about a five-second delay before it begins to change slowly from gray to black. An ecstasy-like substance will usually begin changing color immediately, sometimes even bubbling and fizzing in the beginning (which usually happens with pure powder in gel caps). However, this is not always the case.
If the reagent turns a greenish-yellow color within 20 seconds, this likely indicate the presence of 2C-B (definitely not ecstasy or speed). There are no more tests to perform. Proceed to Step #3.
Note: If the reagent turns a violet color (reddish-purple, not bluish-purple) within 20 seconds, this may indicate the presence of an opiate drug, such as codeine, although it could be something else. Either way, it is definitely not ecstasy or speed. There are no more tests to perform. Proceed to Step #3.
If the reagent does not change a bright orange color, or if it produces a different color change sequence than appears in the Marquis color chart, the pill definitely contains neither ecstasy nor speed. There are no more tests to perform. Proceed to Step #3.