Making OxyContin 'Tamper Proof' Helped Spread Hepatitis C
By Steven Reinberg
Feb. 4, 2019
MONDAY, Feb. 4, 2019 (HealthDay News) -- An effort to make the opioid painkiller OxyContin harder to abuse drove addicted patients to heroin and caused a dramatic increase in hepatitis C, a new study suggests.
In a classic case of unintended consequences, Connecticut-based Purdue Pharma reformulated its powerful and popular drug OxyContin for the right reasons. It became harder to crush or dissolve, thus making it harder to snort or inject for a fast high.
But that change left millions of addicted patients without their drug of choice, so they turned to another opioid -- heroin. Heroin users inject the drug and often share needles, which has spread hepatitis C and resulted in outbreaks of HIV, experts say.
"The fact that we are seeing a rise in hepatitis C infection rates suggests that even if we could stop fatal overdoses, we're going to have long-term public health consequences, because hepatitis C has long-term and very costly effects," said the study's lead researcher, David Powell. He's a senior economist at the RAND Corporation, a nonprofit research organization.
Powell said the OxyContin reformulation probably wouldn't have had this effect if there weren't a readily available, cheap substitute like heroin.
After the reformulation, Powell's team found that in states with high rates of OxyContin abuse, rates of hepatitis C increased three times faster than in other states.
Although the study can't prove cause and effect, the researchers said they found a direct link between the changes in OxyContin and the swell of hepatitis C infections.
conthttps://www.usnews.com/news/health-news/articles/2019-02-04/making-oxycontin-tamper-proof-helped-spread-hepatitis-c
By Steven Reinberg
Feb. 4, 2019
MONDAY, Feb. 4, 2019 (HealthDay News) -- An effort to make the opioid painkiller OxyContin harder to abuse drove addicted patients to heroin and caused a dramatic increase in hepatitis C, a new study suggests.
In a classic case of unintended consequences, Connecticut-based Purdue Pharma reformulated its powerful and popular drug OxyContin for the right reasons. It became harder to crush or dissolve, thus making it harder to snort or inject for a fast high.
But that change left millions of addicted patients without their drug of choice, so they turned to another opioid -- heroin. Heroin users inject the drug and often share needles, which has spread hepatitis C and resulted in outbreaks of HIV, experts say.
"The fact that we are seeing a rise in hepatitis C infection rates suggests that even if we could stop fatal overdoses, we're going to have long-term public health consequences, because hepatitis C has long-term and very costly effects," said the study's lead researcher, David Powell. He's a senior economist at the RAND Corporation, a nonprofit research organization.
Powell said the OxyContin reformulation probably wouldn't have had this effect if there weren't a readily available, cheap substitute like heroin.
After the reformulation, Powell's team found that in states with high rates of OxyContin abuse, rates of hepatitis C increased three times faster than in other states.
Although the study can't prove cause and effect, the researchers said they found a direct link between the changes in OxyContin and the swell of hepatitis C infections.
conthttps://www.usnews.com/news/health-news/articles/2019-02-04/making-oxycontin-tamper-proof-helped-spread-hepatitis-c