• Neuroscience & Pharmacology Discussion Welcome Guest
    Posting Rules Bluelight Rules
    Recent Journal Articles Chemistry Mega-Thread
    FREE Chemistry Databases! Self-Education Guide

  • N&PD Moderators: Skorpio | someguyontheinternet

Loprazolam Solubility in Water

^ yeah, thanks /navarone/, I'm thinking about the pros and cons. Anyway, there will be some people to say it's crazy and dangerous, I know. But I don't intend to take the doses you took anyway ;) But thanks.
 
loulou reed said:
^ Thanks, I'll look at what's inside this liquid. But as it is a pharmaceutical liquid, maybe fillers aren't prevalent or of a nature to clog in the syringe? I don't know. Thanks for the links anyway ;)
edit: that was for Captain Heroin's post
Click to expand...

If the inactive ingredients are known to be perfectly safe for IV, that's one thing. But I'd be careful to check every inactive. If they're all safe you should theoretically be good to go if it doesn't need to be diluted at all. Too high of a percentage of propylene glycol (that hasn't been diluted, if you will, with water, etc) can be dangerous. So you just want to make sure that there's enough water diluting it as well.

dread said:
I will stick to midazolam when it comes to IV:ing benzos. Speaking of "rush", all the other benzos have nothing on midazolam...
Click to expand...

What about loprazolam? I am told it's preferred to midazolam (for someone who is snorting it not IVing). Loprazolam can be shot too.

/navarone/ said:
florazepam would be a great benzo if it wasnt for that fucking triethylamine attached to it making it a long lasting prodrug.

Would there be any way to remove that crap?
Click to expand...

If you IV flurazepam, it won't last as long. That's been my experience at least.

There are active metabolites of flurazepam, which is the problem.

I really like flurazepam and prefer to parachute it.
 
I eventually think there's no added advantage in IV'ing clonazepam oral liquid drops, as when taken by mouth it hits fast and hard, I'd say in less than 10 minutes, maybe even less, like 5 minutes.
 
Captain.Heroin said:
What about loprazolam? I am told it's preferred to midazolam (for someone who is snorting it not IVing). Loprazolam can be shot too.
Click to expand...

Wouldn't know, loprazolam is not available here.

We do have 15mg midazolam pills though, which have midazolam as a water-soluble tartrate salt.

I can tell you, if you shoot a couple of those (micron filtered preferably) you will be wondering what hit you, and possibly also what happened to the last 8 hours... ;)
 
dread said:
Wouldn't know, loprazolam is not available here.

We do have 15mg midazolam pills though, which have midazolam as a water-soluble tartrate salt.

I can tell you, if you shoot a couple of those (micron filtered preferably) you will be wondering what hit you, and possibly also what happened to the last 8 hours... ;)
Click to expand...

3mg of IV midazolam has me like that. :)
 
/navarone/ said:
Did you shoot it? how much?
Click to expand...

No. Well if I shoot it, it will be the first time I IV something, so I'm a little apprehensive of the act. I don't know. I'm not in a hurry anyway, I've got time to think about it. My question is: is there a risk of serious damage like losing my arm or something like that?
 
loulou reed said:
No. Well if I shoot it, it will be the first time I IV something, so I'm a little apprehensive of the act. I don't know. I'm not in a hurry anyway, I've got time to think about it. My question is: is there a risk of serious damage like losing my arm or something like that?
Click to expand...

If you hit an artery instead of a vein, yes. There always is that risk.

Just read up about IVing and see if it's for you. I would suggest to take it orally, but it's really your call.

I'm not going to try to use scare tactics to influence your decision, but please do take a solid look at some resources from the OD Directory about safer shooting, and how to IV guides.

Most importantly, make sure you know everything there possibly is to know about IVing before attempting it. I wish I knew more about injecting before I started.

Feel free to PM me if you do want to go through with this and have any questions, it's good to ask questions before you try IVing. :)
CH
 
Thanks Captain ;) I'll read everything. Just another question: when you say "artery" in the arm, it's the big central vein where people take the pulse of someone?
 
loulou reed said:
Thanks Captain ;) I'll read everything. Just another question: when you say "artery" in the arm, it's the big central vein where people take the pulse of someone?
Click to expand...

Veins carry blood from the extremities back to the heart, and arteries carry blood from the heart out to the extremities.

Yes, arteries do have a pulse, whereas veins do not.

That is one fundamental difference.

Your veins are blue and sit atop of your subcutaneous fat (you can see them, at least in your hands) and possibly in your arms if you are fit.

If you are properly hydrated, vein blood will be dark red. Artery blood will be light red, and "frothy". If you are dehydrated, vein blood can appear light-ish red, but overall you should still be able to tell the difference. Staying hydrated helps.

From what I know, arteries are typically a bit deeper in your flesh than veins are, so if you use insulin syringes with "short tips" you aren't very likely to hit arteries.

But overall, if you happen to begin injecting into an artery, allegedly it is *very* painful. If you're injecting at all and there is pain, please stop injecting.

A solution with a pH that's a bit too acidic or basic could cause a "burn" sensation, and you might actually be going in. But for the most part, the "burn" sensation is bad, and typically means you are missing the shot. What's very indicative of missing a shot (aside for extreme pain - indicating you've hit an artery) is moderate pain "burning" or "tingling" slash itchy sensation. You can see a pocket of liquid building up in your subcutaneous.

Hope this was helpful! :)
 
Ok, thanks. I think IV'ing is not for me, at least not with clonazepam drops which kick in very fast anyway. Not worth the risks... Thanks again Captain ;)
 
loulou reed said:
Ok, thanks. I think IV'ing is not for me, at least not with clonazepam drops which kick in very fast anyway. Not worth the risks... Thanks again Captain ;)
Click to expand...

No problem!

Yeah, the added benefit of oral/sublingual benzodiazepines: the high bioavailability. Off the top of my head, the only two benzos with a lower oral BA than 80% would be midazolam, and triazolam. Even still both are very effective orally.
 
As an update, I found about 0.3mg of loprazolam IV'd was perfect.

It doesn't have a rush like midazolam does though, but its effects do last much longer than midazolam. :)

Either way they are both nice. I haven't tried loprazolam orally but I'm sure it works just as well that way.
 
You must log in or register to reply here.
Top