Limpet_Chicken
Bluelighter
I UTFSE-ed for any threads relating to loprazolam, and found pretty much bugger all.
I got scripted loprazolam a while back when one of the two local pharmacies told me one of my scripts couldn't be filled because the drug company that makes my usual chlormethiazole stopped manufacture, had check out other pharmacies further away in the hope that one of them had some left over from before the drug company ceased manufacture, did get it in the end though.
The loprazolam script was meant to be an emergency stopgap measure, finding a benzo that I had never tried, with the hope it may actually be effective (I don't get much from most benzos, so after searching the relevant databases for benzos came up with
one I had never used, and one that he had never even heard of.
I had my doc do some inquiries, and he found out that the pharmacy that told me that its permanently discontinued was talking complete bollocks, the pharm company still makes chlormethiazole and that they never had stopped production.
So I again get my chlormethiazole script when I go see my doctor and get all my of meds scripted; what is pretty sweet is that he never bothered to cancel the loprazolam. Similar thing happened today, more benzos I wasn't expecting, in this case, nitrazepam. Was on nitrazepam a while back, but hadn't been scripted it in months, as I got my doc to change the 10mg oxycontin for oxy IR capsules, for the reason of it being fast acting, he just looked on his computer for what I have been RX'ed unknown to me at the time, that for some reason he just printed a script for moggies too, as if I had never stopped getting it when I switched to chlormethiazole. Its almost as if, despite my being on 40mg oxycontin twice a day, with what used to be a 10mg once a day, in between the two 40mg OCs, pregabalin, tizanidine and chlormethiazole (it has a fairly narrow therapeutic window, acts more like a barbiturate than a benzo, not identical, but very similar pharmacology to pentobarbital in terms of GABAa subtype selectivity and binding.
Its as if, for he just likes throwing benzos at me for fun
What I know so far about loprazolam, is only whats on the wikipedia, and thats not particularly detailed, intermediate acting benzodiazepine with an active metabolite (anyone know what said metabolite is? its not named on the wiki)
that has roughly the same half life as the parent drug, and likewise, similar potency.
For some reason, it takes a pretty long time to start working once a dose is taken, 2 hours if swallowed on an empty stomach. Not sure why, and considerably longer if taken after eating. Most benzos I have tried (diazepam, nitrazepam, temazepam and lorazepam) acted much faster than that if taken by mouth on empty stomach, Although I rarely ever swallow, dosing them sublingually, or plugged to both increase the speed of onset and avoid first-pass metabolism.
So, anyone here ever had loprazolam, and have experience with the drug? What info can anyone who has experience using this obscure benzo?
I have 1mg tablets, can anyone tell me if insufflating it increases the speed of onset to something more suited for insomnia or a comedown from some other drug or alcohol , insomnia is the reason its RX'd for me, but having to wait two hours or more for it to take effect, when I decide to use a benzo, rather than chlormethiazole is just a fucking nuisance.
The pills are tiny, and would be easily snortable, Anyone tried insufflating it, and if so did it work any faster or hit harder?
(yes, I know most benzos are not water soluble, but that doesn't prevent them being able to be absorbed by mucus membranes
Lastly, for a user with little tolerance to GABAergic sedatives/hypnotics, what would a good strong recreational dose be?
I got scripted loprazolam a while back when one of the two local pharmacies told me one of my scripts couldn't be filled because the drug company that makes my usual chlormethiazole stopped manufacture, had check out other pharmacies further away in the hope that one of them had some left over from before the drug company ceased manufacture, did get it in the end though.
The loprazolam script was meant to be an emergency stopgap measure, finding a benzo that I had never tried, with the hope it may actually be effective (I don't get much from most benzos, so after searching the relevant databases for benzos came up with
one I had never used, and one that he had never even heard of.
I had my doc do some inquiries, and he found out that the pharmacy that told me that its permanently discontinued was talking complete bollocks, the pharm company still makes chlormethiazole and that they never had stopped production.
So I again get my chlormethiazole script when I go see my doctor and get all my of meds scripted; what is pretty sweet is that he never bothered to cancel the loprazolam. Similar thing happened today, more benzos I wasn't expecting, in this case, nitrazepam. Was on nitrazepam a while back, but hadn't been scripted it in months, as I got my doc to change the 10mg oxycontin for oxy IR capsules, for the reason of it being fast acting, he just looked on his computer for what I have been RX'ed unknown to me at the time, that for some reason he just printed a script for moggies too, as if I had never stopped getting it when I switched to chlormethiazole. Its almost as if, despite my being on 40mg oxycontin twice a day, with what used to be a 10mg once a day, in between the two 40mg OCs, pregabalin, tizanidine and chlormethiazole (it has a fairly narrow therapeutic window, acts more like a barbiturate than a benzo, not identical, but very similar pharmacology to pentobarbital in terms of GABAa subtype selectivity and binding.
Its as if, for he just likes throwing benzos at me for fun

What I know so far about loprazolam, is only whats on the wikipedia, and thats not particularly detailed, intermediate acting benzodiazepine with an active metabolite (anyone know what said metabolite is? its not named on the wiki)
that has roughly the same half life as the parent drug, and likewise, similar potency.
For some reason, it takes a pretty long time to start working once a dose is taken, 2 hours if swallowed on an empty stomach. Not sure why, and considerably longer if taken after eating. Most benzos I have tried (diazepam, nitrazepam, temazepam and lorazepam) acted much faster than that if taken by mouth on empty stomach, Although I rarely ever swallow, dosing them sublingually, or plugged to both increase the speed of onset and avoid first-pass metabolism.
So, anyone here ever had loprazolam, and have experience with the drug? What info can anyone who has experience using this obscure benzo?
I have 1mg tablets, can anyone tell me if insufflating it increases the speed of onset to something more suited for insomnia or a comedown from some other drug or alcohol , insomnia is the reason its RX'd for me, but having to wait two hours or more for it to take effect, when I decide to use a benzo, rather than chlormethiazole is just a fucking nuisance.
The pills are tiny, and would be easily snortable, Anyone tried insufflating it, and if so did it work any faster or hit harder?
(yes, I know most benzos are not water soluble, but that doesn't prevent them being able to be absorbed by mucus membranes
Lastly, for a user with little tolerance to GABAergic sedatives/hypnotics, what would a good strong recreational dose be?