L-Theanine

[dogtoy]

I am searching for more information about this amino acid. It is found in tea and is structurally related to glutamate. I am finding lots of opinion about what possible effects l-theanine can have on the GABA, DA, and SERT receptors, with little supporting evidence.

Does anyone have any lines on real experimental results?

I bought some yesterday and took 200mg a couple of hours after my daily 20mg xr adderall prescription. I was more focused and very clear headed but lost many of the distinct amphetamine signals. If l-theanine somehow promotes the release of GABA, then some of the amphetamine effects will blocked, yes? Why would a decrease in dopamine and serotonin cause better focus?

 

[BilZ0r]

Theanine does have quite high affinity for AMPA and Kainate glutamate receptors (10s of µM), ten times lowser affinity for NMDA receptors (~300µM)...

Theanine has been shown to release dopamine, but in that paper, they say they microinject at 500mM... which is like, so fucking rediculously concintrated, I mean, it's so highly concentrated it must have killed all the cells it went near.. they say the injected the drug containing solution at 2µL/min... but I still thing that would totally dominate local cells, so in my mind (and someone with more knowledge of microdialysis could fill me in), this paper must be ignored.