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JaG's Sunlight Stack

Just A Guy

Bluelight Crew
Joined
Feb 2, 2013
Messages
2,558
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Where the heart meets the mind.
“Sunlight Stack”

The objective is to build up self-regulating, optimal levels of neurotransmitters and to heal brain damage done from recreational abuse of substances.

Note: As always, carefully consider your own body chemistry and what you are already putting into your body before supplementing.

Vitamin B100 Stack (100 capsules) per capsule:
One in the Morning

  • B1 (Thiamin hcl) 100mg
  • B2 (Riboflavin) 100mg
  • B3 (Niacinamide) 100mg
  • B6 (Pyridoxine hcl) 100mg
  • B12 (Cyanocobalamin) 100mcg
  • Inositol 10mg
  • B9 (Folic Acid) 400mcg
  • Choline (Choline Bitartate) 10mg
  • PABA 10mg
  • Biotin 100mcg
  • Pantothenic Acid (Calcium Pantothenate) 100mg

Whey Protein Isolate, (81 scoops) per scoop (28g):
One scoop with breakfast, at least 1 hour after l--tyrosine

  • L-Isoleucine 1568mg
  • L-Leucine 2716mg
  • L-Lysine 2716mg
  • L-Methionine 560mg
  • L-Phenylalanine 812mg
  • L-Threonine 1708mg
  • L-Valine 1288mg
  • L-Alanine 1288g
  • L-Arginine 588mg
  • L-Aspartic Acid 2716mg
  • L-Cysteine 728mg
  • L-Glutamic Acid 4788mg
  • Glycine 448mg
  • L-Histidine 420mg
  • L-Proline 1540mg
  • L-Serine 1036mg
  • L-Tyrosine 756mg
  • Potassium 135mg
  • Protein 25g

L-Tyrosine (120 capsules) 500mg, per capsule:
Two in the morning right after waking

  • L-Tyrosine 500mg

Uridine (50 capsules) 300mg, per capsule:
One in morning, with Alpha-GPC and Krill Oil; sublingually

  • Uridine (monophosphate disodium salt) 300mg

L-Glutamine (120 capsules) 500mg, per capsule:
Two in the morning with breakfast

  • L-Glutamine (free-form) 500mg

Alpha GPC, (60 capsules) 300mg, per capsule:
Two in the morning

  • Alpha GPC (L-alpha-glycerlphosphorylcholine) 300mg

5-HTP, (120 capsules) 100mg, per capsule:
One with dinner

  • 5-HTP (5-hydroxytryptophan) 100mg

Pure Antarctic Krill Oil (180 softgels), 1000mg, per softgel:
One with breakfast

  • Krill Oil 1000mg
  • EPA 162mg
  • DHA 104mg
  • Omega-6 28mg
  • Omega-9 92mg
  • Other Omega-3 70mg
  • Phospholipids 400mg
  • Astaxanthin 1mg

Let's discuss!
 
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First I'd like to ask: does it work? Do you feel any effects from this? I wonder this because I've considered trying such stuff for quite some time, but never got around to trying because I've always had doubts about its efficacy. I've used oxiracetam + lecithin and at first it seemed to do something, but then I ran more rigorous tests and it turned out that it didn't do much.

That's quite a lot of thiamine, 200 mg a day, 200 times the recommended daily intake, although ultrahigh doses are considered safe to my knowledge. On the other hand, 20 mg of choline seems like it may be too less? I think the recommended daily intake is like 500 mg, in which case 20 mg sounds insignificant.

Regarding methionine, this study reports that

These results show that methionine supplementation in the diet specifically increases mitochondrial ROS production and mitochondrial DNA oxidative damage in rat liver mitochondria offering a plausible mechanism for its hepatotoxicity.

Which I find a bit weird, because some of methionine is converted into cysteine in the body and cysteine plays a big role in antioxidative processes, like protection of cells from ROS, which would suggest that methionine should have the opposite effect of what is described in the paper. However, this paper suggests the opposite of that (and what is in line with the first paper) and that methionine restriction increases longevity.

Regarding glutamate, glutamatergic receptor over-activity has been implicated in brain damage resulting from benzo, or alcohol, withdrawal (excitotoxicity). This paper reports that decreasing glutamate by scavenging it resulted in less brain damage from excitotoxicity following brain injury, which is of course somewhat different from benzo withdrawal, but I think because the key mechanism behind both is the same (excitotoxicity) it is not worth dismissing, and should be at least explored further. In general, decreased glutamatergic activity (a la NMDA antagonists) has been shown to rather help during withdrawal. Of course, I don't know how relevant this all is in this situation, because a lot of glutamate is catabolized when taken orally, but 10 grams of glutamate a day sounds like a lot. I don't know what the RDI is.

Oh, and congratulations on getting clean! Keep up the good work.
 
First I'd like to ask: does it work? Do you feel any effects from this? I wonder this because I've considered trying such stuff for quite some time, but never got around to trying because I've always had doubts about its efficacy. I've used oxiracetam + lecithin and at first it seemed to do something, but then I ran more rigorous tests and it turned out that it didn't do much.

Well, I've only been on the stack for a little over a week, but assuming it's not placebo effect, I've been more productive and in a better mood at work. I haven't been relying on copious and tedious note-taking as much to stay on track, I've just been "on top of it." Of course, I've abstained from stims for 30 days, from psychs for 60, and from marijuana for 90, and I've been eating healthily and often (lots of beans, fruits -- less sugar, refined foods) so I was already feeling those benefits.

That's quite a lot of thiamine, 200 mg a day, 200 times the recommended daily intake, although ultrahigh doses are considered safe to my knowledge. On the other hand, 20 mg of choline seems like it may be too less? I think the recommended daily intake is like 500 mg, in which case 20 mg sounds insignificant.

I've actually been using this B-Complex for years, especially when I was working out regularly (when I was also supplementing with the whey protein isolate daily, and 3 scoops/day!), and haven't noticed any particular toxicity. Of course, that's paired with lots of hydration and exercise. I think for this stack I will recommend only 1 capsule a day. I'd originally considered 2 a day to help with the normal depletion of b9 & b12 that comes with uridine use. As far as choline goes, the b-complex provides a superficial amount, where the Alpha GPC provides a highly bioavailable form of choline that easily crosses the blood-brain barrier.

Regarding glutamate, glutamatergic receptor over-activity has been implicated in brain damage resulting from benzo, or alcohol, withdrawal (excitotoxicity). This paper reports that decreasing glutamate by scavenging it resulted in less brain damage from excitotoxicity following brain injury, which is of course somewhat different from benzo withdrawal, but I think because the key mechanism behind both is the same (excitotoxicity) it is not worth dismissing, and should be at least explored further. In general, decreased glutamatergic activity (a la NMDA antagonists) has been shown to rather help during withdrawal. Of course, I don't know how relevant this all is in this situation, because a lot of glutamate is catabolized when taken orally, but 10 grams of glutamate a day sounds like a lot. I don't know what the RDI is.

It will be worth cutting out the L-Glutamine after a month to see if I notice any difference. If I don't, then it's likely not even necessary. Out of all of this, the L-Glutamine is especially experimental for me.

I cut the B-100 and L-Glutamine amounts in half. Let's try that. I'll continue with what I did originally, and then halve it after a month.
 
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I've actually been using this B-Complex for years, especially when I was working out regularly (when I was also supplementing with the whey protein isolate daily, and 3 scoops/day!), and haven't noticed any particular toxicity. Of course, that's paired with lots of hydration and exercise. I think for this stack I will recommend only 1 capsule a day. I'd originally considered 2 a day to help with the normal depletion of b9 & b12 that comes with uridine use. As far as choline goes, the b-complex provides a superficial amount, where the Alpha GPC provides a highly bioavailable form of choline that easily crosses the blood-brain barrier.

My bad, I failed to notice the alpha GPC. Wikipedia says that 50 mg/day of thiamine seems to improve cognition without side-effects, so that's good I guess.

It will be worth cutting out the L-Glutamine after a month to see if I notice any difference. If I don't, then it's likely not even necessary. Out of all of this, the L-Glutamine is especially experimental for me.

I was talking about glutamate not glutamine. The glutamate that is in the whey protein, so you can't take it out sadly. In any case, those points in my first post were with more just informative purpose than anything, I can't tell whether the stuff will affect you negatively or positively, I guess it's a matter of experimenting. You know, kind of "just sayin'" to consider in case you weren't aware.

Good luck!
 
Well, I'm still using the stack, and I've noticed that when I wake up, I'm ready to get stuff done. The slight headaches I got in the beginning (I think from the uridine) have gone away. Food cravings at an all time low, as I have been able to stick to my diet pretty easily -- which includes black or kidney beans twice a day, spinach at least once a day, and berries at least once a day.

I really look forward to the l-tyrosine first thing in the morning, before breakfast.
 
I'm just thinking about this in terms of different metabolisms. The whole "RDA" philosophy can be a little toxic at times. For instance, if someone only really needs 1,000IU of vitamin D and they're taking 2,000, that extra 1,000 behaves like a toxin in the body. It's an excess that must be purged. Some people need more and some need less. Most of the research I've read on vitamins across the board indicates that they are poorly absorbed, and the remainder has to get dumped by the liver, kidneys, or other waste channels. I wasn't really sure what to believe until my health started declining, and I tried to compensate by cramming more nutrients in through vitamins. It makes you weaker. If you have strong vitality you won't feel the hit, but it's there.

JAG, no offense, but that's a loooong list you've got going there. You're better off getting your nutrition from food. If your body doesn't want to uptake something, it's not going to do it. Trying to force it to is violating it. That's if you believe the body should be treated with compassion and its intelligent way of doing things respected. I know that's not standard fare in the modern world though.

One thing I've been reading up on is a low calorie, high nutrient diet. These diets are the key to longevity and better health. High calorie diets lead to rapid aging. It may be why your food cravings decline as you increase nutrients. I'm just wondering if there's a way to get very rich nutrition at low calorie through foods exclusively? It would take some brainstorming, but yeah.
 
Good points, Foreigner. I actually have a pretty good diet going along with this. It's pretty low-cal compared so a typical American diet. It's mainly eggs, beans (black or kidney), and berries (mainly blueberries) with a bit of pasta here and there or chicken or beef. High nutrition with that. I'm still researching the toxicity of nutrition overload...
 
Well, I've since adjusted the dosages -- mainly there's no need to supplement most of these twice a day -- I have been using the stack for a few weeks now, and I feel great. I'd been smoking cigarettes for a few months after my vape took a shit, and got to say was really enjoying them. Then I decide I'm going to give up all tobacco, for good, for Lent. And so on Ash Wednesday, my daughter broke my remaining cigarettes over the trash can and I haven't succumbed yet!

Strangely, I am extremely fit, even though I haven't been working out, (although my job is very physically intensive). Don't know why I look like I've been taking anabolics but I haven't...
 
I would just like to warn both of you against the pseudoscientific bullshit regarding diets, because it's one of those fields where objective information is rare and bullshit is vast. It is true that severe overdoses of certain compounds, including vitamins, can lead to toxicity, but that is not the case with everything. Some vitamins, like niacin, have studies claiming that exceeding the normal intake by 10-100 times is not harmful. Then again even some proteinogenic amino acids, like methionine, have studies claiming that daily overdosing may lead to oxidative stress and more rapid aging (sources in my first post). So there's no one-fits-all way of dealing with it, and while I agree that RDA can be misleading and should be taken only as an approximate estimate, it is incorrect to say that taking supplements is definitely harmful. You have to remember that our body is a dynamic system and it is designed to produce, uptake and destroy everything "on-demand", so taking small excess of something that the body deals with all the time is unlikely to cause a change.

Personally I hold the belief that since I don't understand the way our body works to a sufficient extent, I try to avoid manipulating my diet in a major way through supplementation and rather rely on obtaining everything I need through a regular diet.
 
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