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Misc Isopropyl alcohol 99% dosage/dilution

DistyBoi

DistyBoi

Bluelighter
Joined
Nov 17, 2011
Messages
307
My friend has 1L of IPA and insists its ok to drink as long as you are very careful and dilute it enough. I've looked online and it does seem to be ok to drink (its not like methanol at least and is much more like ethanol), but still seems like a bit of a silly idea. But we're going to have to try it now I've looked into it lol.

How should we go about this? Its 99% pure IPA. I presume diluting it by adding IPA : water @ 1:3 will leave a solution of ~25% and that will be ok?

Some info:

"Acute toxic exposure (via ingestion) seemed to have, from what i read, quite similar symptoms as u would expect from regular ethyl alcohol - CNS depression (exacerbated by acetone - its main metabolite), drowsiness, vomitting, etc - only "with unconsciousness, coma and death following massive exposure" (LD50 for Isopropanol in rats 5050mg/kg; LD50 for Ethanol in rats 5628mg/kg).
Some facts from inchem.org:
80% of an oral dose is absorbed within 30
minutes. Absorption is complete within 2 hours
although this may be delayed in a large overdose (Ellenhorn, 1988 ).

Isopropyl alcohol distributes in body water with an
apparent volume of distribution of 0.6 to 0.7 L/kg. Two hours
are required for complete tissue distribution (Ellenhorn, 1986).

Isopropyl alcohol most closely follows first order
kinetics, with a half-life of 2.5 to 3.2 hours (Daniel, 1981).
The elimination half-life of the active metabolite,
acetone, is significantly prolonged to about 5 hours in rats
(Teramoto, 1987) and 22.4 hours in man (Natowicz et al., 1985).

20 to 50% of an absorbed dose is excreted unchanged. Most
isopropyl alcohol is oxidized in the liver by alcohol
dehydrogenase to acetone, which is probably further
metabolized to acetate, formate, and finally carbon dioxide.
Acetone may contribute to the CNS (central nervous system) depression seen in
isopropanol poisoning.

20 to 50% of an absorbed dose is excreted unchanged (2% of dose excreted
in exhaled air).
Acetone is slowly eliminated by the lung (40 % ) or kidney. Clinically
insignificant excretion occurs into the stomach and salive (Teramoto, 1987)."

So from a purely objective and speculative standpoint, getting high on isopropanol doesn't seem too out there, if one were to measure precise doses of known (and preferably tested) purity substance, but the body's reaction does seem to be more violent towards it and it doesn't sound fun or enjoyable at all ...

Wouldn't feel right if I didn't say DON'T TRY DRINKING THIS AT HOME at the end of this post.
 
Last edited by a moderator:
Sounds like a really really bad idea to me. I don't think many people on a harm reduction forum would recommend drinking ISO.
 
I tried this when I was 17 and couldn't obtain real booze legally. It's two times stronger than ethanol, and when I took 50 ml, it felt like I had drunk a six-pack of beer.

Like you know, its metabolized to acetone, and an unpleasant thing about this is that you can smell the acetone in your own breath for a long time after taking a dose of IPA.

Note that even though there's no real evidence that it's more toxic to organs than ethanol, it still irritates stomach more than regular booze and can cause hematemesis (puking blood). Also, no one knows what happens if you use IPA regularly for a long time.
 
^Agreed.

While ethyl alcohol is just as toxic as isopropyl alcohol, as mentioned before, the metabolite of acetone is dangerous. Also, puking blood is NOT something you want to do. Since drinking regular old ethyl alcohol will give you the same result but with less risk of extreme stomach bleeding.

All alcohols are dangerous drugs.
 
what everyone else just said.

dont be a fucking tool. buy a few cans instead man. i really dont see the point.
 
Without wanting to sound a "fucking tool" isn't acetone present in many other drinks, flavorings and preservatives, and is able to be used in such as its been shown to be relatively benign and non toxic when ingested?

@ NeighborhoodThreat: I agree all alcohols are pretty nasty chemicals drug wise, but why would IPA make you cough up blood any more than Etoh?
 
DistyBoi said:
Without wanting to sound a "fucking tool" isn't acetone present in many other drinks, flavorings and preservatives...
Click to expand...

I agree. This thread needs to be resolved correctly, or a bunch of people are going to end up reading this thinking no one thought it fully through.

FYI - don't drink isopropyl alcohol.
 
polymath said:
I tried this when I was 17 and couldn't obtain real booze legally. It's two times stronger than ethanol, and when I took 50 ml, it felt like I had drunk a six-pack of beer.

Like you know, its metabolized to acetone, and an unpleasant thing about this is that you can smell the acetone in your own breath for a long time after taking a dose of IPA.

Note that even though there's no real evidence that it's more toxic to organs than ethanol, it still irritates stomach more than regular booze and can cause hematemesis (puking blood). Also, no one knows what happens if you use IPA regularly for a long time.
Click to expand...

^This. IPA is more irritating to the stomach lining than regular old ETOH
 
A buddy from Russia said they drink it sometimes there too...

Its just a theoretical question
 
Don't do it!! It's seriously not worth the risk! Can't you obtain normal alcoholic beverages?!? The lethal amount for a healthy adult is just 6 to 8 ounces. Even if it doesn't kill you it can make you seriously sick. It is not worth it! A quick Google search turns up all sorts of nasty risks:
http://www.livestrong.com/article/125365-dangers-drinking-isopropyl-alcohol/
http://wiki.answers.com/Q/Can_you_drink_rubbing_alcohol
http://www.ehow.com/how-does_5200289_effects-consuming-rubbing-alcohol.html

Even the source you quoted as rationale in your post says "the body's reaction does seem to be more violent towards it and it doesn't sound fun or enjoyable at all"

and "DON'T TRY DRINKING THIS AT HOME"
 
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