• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

Phenethylamines Is there an easy method to convert 2c-b HBr to HCl?

Status
Not open for further replies.

MrMolecule

Greenlighter
Joined
Jun 15, 2024
Messages
2
As the title suggests, is there an easy method of converting the 2c-b HBr salt to the HCl salt?

I realize from the synthesis literature that it can be done in a lab relatively easily. BUT is there a method of conversion that is less... costly. I'm not necessarily looking for intermediate cleaning steps, as the assumed starting HBr is relatively clean.

In this scenario the purpose of conversion is for testing subjective differences between the 2 salt forms. I know according to the chemistry and pharmacology that they SHOULD be the same besides the HCl salt being more potent by weight, but that's besides the point.

As long as the conversion ends in a safe and useable HCl salt form of 2c-b then I'm satisfied.
 
Dissolve in water, freebase with NaOH or similar, extract freebase into non polar solvent, gas non polar layer with HCl
 
Alright, so it sounds like it wouldn't be too difficult then.

Any suggestions for the NPS? What is it most soluble in that isn't too difficult or sus to acquire?
 
DCM, but I have no idea about difficulty or if it's suspicious to aquire
 
See Phikal and Rhodium Archive on Erowid? Freebasing with NaOH extracting with CH2Cl2 (don't know other solvents maybe we should make a list??), distillation at 115-130 at 0,4 mm/Hg (don't know how important that is and if there are other ways, this might be the tricky part). dissolving in water and acetic acid and titration with HCl under vigerous stirring.

Seems pretty straightforward to me assuming you can get CH2Cl2 and a magnetic stirrer might me handy or even necessary?

Again a list of solvents for 2C-B would be handy and since the hydrates and polymorphs are a problem you want your freebase totally free from water that's why the distillation under 115-130 C, but maybe there or probably sure are other ways to get rid of the water.

Actually I understood that if you can get the HBr to crystallize nicely the HBr salt might be preferred because you can snort it without burning your nose if you want a shorter experience.
 
Honestly, this is technically synthesis talk which we do not allow on Bluelight. So I'm closing the thread.

If you're going to do this, do not go below pH 6....
 
Status
Not open for further replies.
Top