• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

Health Is natural better than synthetic?

red22

Bluelighter
Joined
Nov 23, 2009
Messages
1,200
I'm just not in agreement with synthetics. I've experimented with a lot of these different things over a period of years, and I sat down one day and said, you know I'm just buggering myself up with this shit, and it's not taking me anywhere that I can't get with psilocybin, DMT, LSD, and mescaline. These are naturally occurring.[ * ] They work. Your body has a "history" of experience with them. People have used them for thousands and thousands of generations, and we've adapted to them because they exist in nature, they're there for us to use, they're the planetary hormones that allow us to bring our consciousness forward to the next level. They've always been used this way.

Owsley Stanley. Interview with an Alchemist: Bear Owsley Interview. 2010-01-10. Bruce Eisner's Writings. https://archive.vn/RAUXH


--------------------------------------------------------------
I’ve tried probably 20 tryptamine analogs.

None of them beat good quality shrooms. Seriously.

You have to get good shrooms tho.

MET was nice tho…. Didn’t like the DMT analogs. They were great actually, but came with a hangover.

The hangover is what I didn’t like about analogs.

Shrooms give you the exact opposite of a hangover.[**]
--------------------------------------------------------------
ZydePunk77, 2024-09-17, re: The best base tryptamines in your experience and why?


*I believe that they will find a plant which contains the exact diethylamide of lysergic acid in natural form. In alkaline alcoholic medium the isomers of the amines of lysergic acid will reach an equilibrium. This equilibrium will be a certain percentage of the iso compound, and a certain percentage of the normal compound. Of all the compounds listed experimentally by [Hofmann], LSD has the highest ratio of active to inactive isomers in the equilibrated mixture, it runs 88-12. Of all the compounds, and it lists about 20 of them, it has the highest ratio of active to inactive. This means that nature favours the active form of LSD over the inactive by a considerable margin.


**I've also heard of people taking small hits of DMT and 5-MeO-DMT as a quick refresher, for example:

I love low dose dmt it seems a safe stimulant and excellent for getting rid of a hangover or waking you up if you've smoked too much weed the night before.. Everything becomes so much better it focuses the mind and rids the limbs of restlessness and lethargy, clears up headaches and aches and pains, basically makes you feel well with no side-effects at all!

@SanGaz, 2009-05-08, http://www.bluelight.org/vb/threads...tion-thread!?p=7400739&viewfull=1#post7400739

And I'm wondering which one works better for this.

 
Last edited:
2C-x grant me rich experiences. I don't think I would have dared to explore psilocybe cubensis and LSD as much as I have the psychedelic phenethylamines. They just don't seem to align with me. Nothing about these experiences with synthetic phenethylamines is artificial or lacking for me. I've said it once and will say it again - I believe mankind is natural so anything we make is part of nature as well. Pick what you like for whatever reason you have, but please don't discredit other people's experiences just because you can't get behind it. One man's junk is another man's treasure.
 
My issue with synthetics is that I can feel the "ceiling" of their effects. There isn't the same depth level as natural and I'm not totally sure why. Also I am concerned about how synthetics are broken down by the body vs. naturals. Even though a natural and synthetic molecule have the exact same physical structure, I do not believe that they behave in a 1:1 way. There is a nuance there that hard science isn't currently able/willing to look at.
 
My issue with synthetics is that I can feel the "ceiling" of their effects. There isn't the same depth level as natural and I'm not totally sure why. Also I am concerned about how synthetics are broken down by the body vs. naturals. Even though a natural and synthetic molecule have the exact same physical structure, I do not believe that they behave in a 1:1 way. There is a nuance there that hard science isn't currently able/willing to look at.

By synthetic, I was implying "not found in nature", but taking it a step further and distinguishing between natural chems and synthetic copies of those same chems is also a discussion. I've noticed a shocking difference between chemical extractions of B. caapi and B. caapi tea. The extractions were like VHS recordings of the original experience; these acid-base extractions I had were the worst. Even caapi paste (boiled down B. caapi) feels damaged. Even pharmaceutically pure harmine from China feels damaged. The only form of caapi that has provided me with a nice experience is caapi tea. See this post of mine: Am I the only one? (quality of different ‘harmala’ products)
 
For some drugs, mescaline, and 5-meo-dmt I see no reason to use the natural version. Both are endangered but even if natural sources were in abundance but the toads and cactus have other other alkaloids in them that make you sick. I like to know exactly what I am taking. I dont really take any natural psychedelics these days. shrooms very rarely, DMT is just scary. The whole natural is better thing just kind of sound like hippy shit to me, better living thru chemistry I say
 
Come to think of it, there are some maritime compounds extremely close to 2C-B. It wouldn't surprise me if that one was found out to be natural as a trace compound some time!
 
Depends where you fall on calling acid a synthetic. But actually, i guess I prefer sythetics. I'd rather take 4-aco-dmt than shrooms because of the consistency and convenience. Ive never had cactus but I have synthetic mescaline and been able to completely avoid nausea.

I don't know if I feel one is better then the other though I think it really is preference. And there's something quite charming about grinding up your shrooms and making a cup of tea, not to mention being able to grow them and make your own medicine.
 
By doing anything in particular?
I stagger the dose. 200mg every 20 minutes over an hour or so but otherwise no. I always hear about how nausea and purging is an expected part of the experience with cactus and I have a real aversion to nausea and while I have no personal basis for comparison having never eaten cactus I've been able to take synthetic mescaline HCl with none what so ever which was a real relief.
 
Last edited:
"Alexander Shulgin, American chemist, told Albert Hofmann that he preferred LSD to 2C-B."


I don't doubt it, as I heard Shulgin really liked LSD from people close to him, but is there any source for that particular statement?
 
By synthetic, I was implying "not found in nature", but taking it a step further and distinguishing between natural chems and synthetic copies of those same chems is also a discussion. I've noticed a shocking difference between chemical extractions of B. caapi and B. caapi tea.
I would love to have seen and felt the emotions that when after LSD was discovered, later on LSA was found in nature. That has to be exciting.

I go back and forth. I do think natural substances have a little extra "spirit". But then I have had as deep and satisfying trips with 4-ACO-DMT and LSD. So I am not sure what I believe. I have always leaned towards natural substances over synthetic. But can not say there is a big difference. I love cactus and never really get nausea with the way I consume. T&W powder and eat a bagel and have a few hits of cannabis. I can say I never tried synthetic mescaline.

Here is what we need to find in nature as natural: A ketamine type substance and a gabapentinoid type substance. It would also be interesting to find a synthetic type Salvinorin type substance.
 
They all did it together and it was wonderful and trippy. And it was legal for years. ❤️‍🔥

And intellectual to study it at the University and trip together.

I will look for more source or publishing to post.

But yes part of University and mind expanding learning and indulgence. Back then.

I heard it was amazing from this lady that was a teacher that I had known and she told of how she had went to Berkeley.

Her dad wanted to pull her out of the school because they all tripped on the lawn. just some trivia. :eek:
 
Many substances can actually be natural. Like poppy flowers. Which seem somehow to be illegal now as well. 🤔

And abuse is part of the rational and motivating fractions for regulating. Also. 🤔

Or abuse is also and excuse to put a governor on something to have controlled somehow. :\

~~~~

The thing about natural being better is that I thought it would be easier to obtain. Once things start growing. ;)

It depends on the quality and effects. Or consequences of course.
 
Poppy plants were always illegal, it's just that no one cultivates them for opiates so the law isn't enforced.
 
There nothing about a compound being naturally derived that makes it “better”

Its compound specific.

Cyanide strichnynne botulinum toxin batrachotoxin and tetrodotoxin are all natural and not pleasant chemicals.

If you grow the plant yourself there are no cutting agents, no unknown toxins, cyanide, unreacted precursors, etc and you likely don't have to mess with ultra low doses either. Assuming you got the right plant natural substances are somewhat self limiting in their dangers.

Technically when you order a synthetic drug you would need to assume that this might be the wrong substance, even from an otherwise reputable vendor. Such mistakes do happen. A friend once bought "ODSMT" and took 50mg. This turned out to be a massive overdose of something else. He first passed out and was found unresponsive on the floor. Later he started raging like a mad man against 4 paramedics before he got shot down. He made it but was hospitalized. The substance he got turned out to be active at 3mg.

You therefore would need to start very low and slowly up your dose to the expected range. Who does that with every shipment of drugs you get?
 
Top