Mental Health Is my combination of Mirta, Fluoxetine, Ritalin, Seroquel safe?

Hagbard_Celine

Greenlighter
Joined
Nov 30, 2016
Messages
1
Hi Bluelighters,

currently Im on some pretty strong combination of meds because of a depression which started with a complete loss of the ability to sleep about 4 months ago. :sus:
To deal with my disorder I now take 40 mg Prozac in the morning to cope with the depression per se and I also take about 20 mg Mirtazapine and 25 mg Seroquel in the evening to get me into sleep mode (+ some valerian and sometimes melatonine). In the last weeks I started to feel better regarding the depression symptoms and have the feeling that the Prozac is working its magic. So far so good.

Last week I was also diagnosed with an attention deficit disorder (ADS) and my doc wants me to start taking Ritalin (immediate release version to find the appropriate dosage).
Now Im more than a bit worried about the possible side-effects regarding drug interactions. Im especially worried about suffering a Serotonin Syndrome, triggered by the addition of Ritalin. I also worry about interactions regarding the serum level of the different drugs in my bloodstream.
As far as I know Fluoxetine as well as Methylphenidat seem to inhibit CYP2D6 which could lead to elevated serum levels of both Fluoxetine as as well as Ritalin. I read about the possible side effects regarding CYP2D6 enzyme on this site: http://www.corepsych.com/2006/11/adderall-prozac-and-paxil-problem-not-solution/
Doctor Charkles Parker (author of the website) suggests switching Prozac to Venlafaxine, which does not inhibit CYP2D6.

Has anyone been on such a combo of meds or a maybe similar combination?
Is there reason to worry about adding Ritalin to my daily medication?

thank you!
 
Last edited:
Top