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Intranasal cannabis tincture?

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dputty

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Joined
Apr 14, 2009
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72
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Missouri
I recently bought this product that shoots capsaicin and some other ingredients into your nose to relieve headaches. I was wondering if I were to put a cannabis tincture into this nasal spray bottle, would it be effective? If so, more or less effective than a sublingual administration?
 
Nope I do not think it would work as it doesn't absorb well nasally, not sure about sublingual either. I've heard of hash oil being used sublingually and having effects but I think oral would be your best bet. Cannabis tinctures such as green dragon can fuck you up.
 
Capsaicin is a fat. I think cannabinoids might dissolve readily into capsaicin.
 
I only said I think, I don't think there's any data on the solubility.
 
I seriously dont understand why people insist on using less effective means of administration for the hell of it. But the answer is yes it will have some sort of effect, though the bio-availability will make it horribly inefficient.
 
As a matter of fact, you can make just about anything sublingually bioavailable when you suspend it in alcohol. Check this out http://www.youtube.com/watch?v=Wqje5StAhCI. And the reason people would want to use a sublingual or intranasal ROA is because they are taking the cannabis to ease throat pain which is made worse by inhaling smoke. The reason they wouldn't just want to orally ingest cannabis is because cannabis absorbed in the gut has a very inconsistent bioavailability. Not to mention your dose has to be higher when you ingest, and you must commit yourself to a very long lasting effect, that maybe you don't have time for. In addition, THC causes delayed gastric emptying, and it causes the LES (lower esophageal sphincter) to relax. So your stomach is releasing more acid to deal with the food that is sitting in the stomach and is refluxing easily into your esophagus because your LES is relaxed and can't keep it out. This effect is made much worse by ingesting cannabis as it is directly absorbed into the gut and you are taking a much higher amount of THC than you would be if smoking or sublingually dosing.

So,,, I know that THC is readily absorbed into the mouth when it is in alcohol, I am asking if it would work any better if you sprayed it in your nostrils instead... or would the alcohol cause lots of burning to make it not worthwhile. I ask this because I have no experience with nasal administration for any substance.

As for the interest in how caspaicin can help headaches... Caspaicin is a vasodilater, meaning it dilates your blood vessels, many times when you have a headache your blood vessels constrict, causing further pain. In addition, your body responds to caspaicin as it would to a pain signal (even when it does not cause pain) and your body releases endorphins. http://74.125.95.132/search?q=cache...rphins&cd=2&hl=en&ct=clnk&gl=us&client=safari
Oh, and THC is not only fat soluble, it is alcohol soluble as well.
 
^Nope. It's a oromucosal spray. Spray under the tongue or on the inside of your cheek.


Also, capsaicin does cause the release of endorphins, but also causes the rapid dumping of "substance P" a pain-signaling peptide. It takes a lot longer for cells to make this peptide than it does for it to dump and endorphins are in ready supply the whole time. A few minutes of burning, then some relief.
 
sativex contains both thc & CBD extracted from Cannabis material leading many medical user to report side effects more marijuana-like then Marinol(synthetic delta9THC).
 
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