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I Like to Draw Pictures of Random Molecules

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Yep, also considering that some 2' substituted amphetamines (eg:2-FA) where ery appreciated bu many users.... beta methoxys are hard to synth and the obly one famous so far is phenmetrazine.
My only doubt on the substance it's compformation. It would be a bendodehydrofuran molecule with and ethanamine sticking sideways....so somehow far from the classic planar structure of ordinary phenyethylamines.
But who knows..this drug could become the drug of the year especially with some wacky substitution on the 4th carbon like fluorine a la 4-FA.
 
This one looks very interesting but could be quite hard to handle and crystallise.
240px-Fat_structural_formulae.png
 
hx_ said:
This one looks very interesting but could be quite hard to handle and crystallise.
240px-Fat_structural_formulae.png
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Aesthetically I really like it. The two acetyl groups call to mind cocaine, to me the other three oxygens appear functionally odd however, the rest beside looking much like the amphetamine/dopamine type skeleton. What about it personally looks interesting to you? Did you base it off of a combination of any other specific compounds?
 
Nagelfar said:
Aesthetically I really like it. The two acetyl groups call to mind cocaine, to me the other three oxygens appear functionally odd however, the rest beside looking much like the amphetamine/dopamine type skeleton. What about it personally looks interesting to you? Did you base it off of a combination of any other specific compounds?
Click to expand...

Haha no, it's olive oil ripped straight from wikipedia, was wondering how many people would think it to be a drug!
 
Nagelfar said:
Aesthetically I really like it. The two acetyl groups call to mind cocaine, to me the other three oxygens appear functionally odd however, the rest beside looking much like the amphetamine/dopamine type skeleton. What about it personally looks interesting to you? Did you base it off of a combination of any other specific compounds?
Click to expand...

Haha no, it's olive oil ripped straight from wikipedia, was wondering how many people would think it to be a drug!

What about this deliriant/depresant?

:P
 
Aesthetically I really like it. The two acetyl groups call to mind cocaine, to me the other three oxygens appear functionally odd however, the rest beside looking much like the amphetamine/dopamine type skeleton. What about it personally looks interesting to you? Did you base it off of a combination of any other specific compounds?
Click to expand...
Of a rather stimulant shadow casting form. However that is not to claim anything of its potential outside of cargo cult molecular biology. The only type of which I have any schooling in.
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Hook, line and sinker :D

hx_, if you're interested, that's not specifically olive oil, it's the basic backbone of all edible fats and oils, those "R"s are placeholders, indicating that different hydrocarbon chains can be in those positions. Olive oil isn't a pure chemical, it's a mixture of different chemicals with the basic structure you've shown, plus various other tasty/colorific compounds. Of course, you probably don't give the slightest fuck, but just wanted to troll the thread, in which case, job well done. :)
 
Vader said:
Hook, line and sinker :D

hx_, if you're interested, that's not specifically olive oil, it's the basic backbone of all edible fats and oils, those "R"s are placeholders, indicating that different hydrocarbon chains can be in those positions. Olive oil isn't a pure chemical, it's a mixture of different chemicals with the basic structure you've shown, plus various other tasty/colorific compounds. Of course, you probably don't give the slightest fuck, but just wanted to troll the thread, in which case, job well done. :)
Click to expand...

Yeah I thought it wasn't likely to be the one chemical, almost all organic and natural things are complex compounds n admixtures. Didn't know about the placeholder thing, you learn something new every (or most) days. Regardless it doesn't look like a very "rigid" molecule so I assumed it wouldn't be able to bind to any significant receptors.
 
hx_ said:
Haha no, it's olive oil ripped straight from wikipedia, was wondering how many people would think it to be a drug!
Click to expand...

I assumed with the R¹, R² & R³ substitutions that it was a definite postulation. I knew it couldn't be anything "specific" (as already stated, it's a lipid back bone)

It does look like it has some phenethylamine backbone (minus the oxygens etc.) So that was a good one to select.

Good show, hah.
 
Since I seem to have a fetish for the MPH molocule

2ms20xu.png


the C=O looks a bit out of place, so perhaps drop that? stim me thinks

2zh1p9z.png

opiod?

2mqnqqw.png

strange thing

359xqtk.png

canabiniod?
 
^^ I doubt any of the structures you made will have the effects you think. The "strange thing" molecule doesn't have any phenyl rings, and I'm pretty sure that the second phenyl ring is important for DAT binding (Someone correct me if I'm wrong).

However, I'm definitely not saying they are completely inactive. Your "opioid" structure looks like it could have antagonistic action at NMDA receptors if you had a nitrogen coming from the cyclohexylamine ring.

~snr
 
Not sure how that would work, but the fact that theres no indole backbone makes me think it wouldn't work.
 
dip12 said:
Thiosilocin
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The closest analogue I could find removed the hydroxyl, added a 1-phenylsulfonyl group and mentioned 5-HT6 receptor activity (see the patent plain text or w/images). However, sifting through drugs that work at this site it seems removing the phenylsulfonyl group might reduce or abolish such activity. As for 5-HT2A it might work though I personally wouldn't count on it.
 


How about something like this. A bit strange looking i know, but i was reading an old post by fastandbulbous ( http://www.bluelight.ru/vb/threads/167978-Acid-dragonflies-and-the-5HT2A-receptor ) about how having an electronegative substituent on the beta position increases activity. So the molecules has electronegative substituents at the 2 and 5 positions similar to the 2c's. There is then also the electronegative substituent at the beta position, and all the substituents are members of a ring to keep the molecule more planar ( i know the dioxane ring isn't perfect but its an improvement on having the substituents free to rotate). Also the molecule could have a halo, alkyl thioalkyl ect substituent at the 4 position. Any feedback? My pharmacology knowledge is very limited as you can probably tell!
 
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