CrimpJiggler
Bluelighter
- Joined
- Aug 28, 2011
- Messages
- 241
I'm trying to get clean at the moment after a polydrug habit and the worst withdrawal symptom I have is akithisia. Its like restless leg syndrome but its not confined to the legs. I don't get it in the legs at all, I get it mainly in my chest. Anyone else here have experience with this symptom? Have you found any methods of remedying it? I know they prescribe selective dopamine agonists like bromocriptine for it, so I'm gonna ask my doc to prescribe me something like that to try soon enough. They prescribe MAOIs like selegiline for Parkinsons disease. I brewed up some caapi tea (a plant containing MAOIs like harmine) last week and have it in my fridge, I want to try it when I'm been off the trazodone for a few days and that restlessness kicks in.
If you have experienced this symptom, can you share your experience on the things you've tried in order to remedy it. I'll list all the things I've tried so far.
THINGS THAT WORK:
DXM - This definitely works, it makes me extremely relaxed for about 4 hours and when it wears off I'm still relaxed, even the next day. The downside is its not something you can use regularly since tolerance builds up rapidly.
Exercising - I find that theres a certain threshold, you need to exercise heavily enough to reach this threshold then the agitation goes away, and doesn't come back for at least 30 minutes after I stop exercising. The best way to reach this threshold I've found is skipping. 10 minutes of skipping has me completely wrecked, I can't even do 10 minutes straight without taking small breaks yet.
THINGS THAT KIND OF WORK:
Amphetamine - Obviously this works since it releases dopamine but when it wears off, the restlessness comes back hard, making it impossible to sleep.
AMT - I get a similar effect to DXM while I'm on it, but when it starts wearing off the restlessness comes much worse. I tested it out yesterday and when it wore off I couldn't sit still.
Iboga - The most I've done so far is 8g of root bark, at that dose I barely get any psychedelic effects, instead I'm extremely relaxed and euphoric similar to AMT and DXM, but like AMT, I get extreme restlessness when it wears off. I'm gonna experiment with microdosing though.
Opiates - I've only tried codeine and DHC so far, they seem to help a bit but the akithisia is still there.
Gabapentin - Hit and miss. Sometimes it helps, sometimes it seems to amplify the akithisia. Gabapentin doesn't effect me in a normal way though, it effects me more like a stimulant than a sedative.
Trazodone - It kind of works. When I take it to sleep, the aggitation comes and goes the next day, then if I don't take trazodone the following nights, I get about 2 or 3 days with no restlessness before it comes back.
Benzos - They suppress the physical feeling of restlessness but the mental restlessness is still there. They're way too addictive to use as a daily remedy.
GHB/Phenibut - Hit and miss. I did phenibut daily for a few weeks and sometimes I would be completely relaxed, other times the akithisia was much worse than usual. The agitation would come on strongly the next day after doing phenibut. Also way too addictive to use as a regular remedy.
Nu-nu - Nu-nu is a snuff containing mapacho (nicotiana rustica, aka Indian tobacco) and mocambo bark (a tree closely related to coco). Snorting a bump of it seems to relax me initially but after about 20 minutes I end up more restless. I need to experiment more with this though, I've only tried it twice so far. I believe the relaxation is caused by nicotine, Indian tobacco contains up to 20 times as much nicotine as regular tobacco (nicotiana tabacum). I'm not a smoker so I don't know if smoking tobacco helps with akithisia.
THINGS THAT DIDNT WORK FOR ME
Picamilon, rhodiola rosea, magnesium (I've only tried oxide, I hear there are salts with much higher bioavailability), l-dopa (maybe I need to try a higher dose and I also want to try taking carbidopa with it which prevents it from being metabolised in the body before crossing the blood brain barrier), gotu kola, valerian root extract, l-theanine
MY LIST OF THINGS I WANNA TEST OUT
MAOIs - They should help by preventing dopamine from being broken down by MAO. I'm gonna try caapi tea first since I have it but selegiline sounds the most promising. I read that b. caapi has been proven to remedy Parkinsons disease symptoms, but the pharmaceutical companies couldn't figure out how to patent it so they moved onto other MAOIs.
Dopamine agonists - The only ones I know of are bromocriptine and apomorphine. AFAIK, bromocriptine is a selective D2 agonist which is prescribed for RLS. Apomorphine forms from decomposition of morphine and is a potent emetic. Its a non selective dopamine agonist, it binds to both D1 and D2 receptors.
Memantine - An NMDA antagonist with some D2 activity.
Kambo - Its venom from a species of Amazonian tree frog. It has lots of medicinal properties and in my experience, it makes you feel relaxed and good for the whole day after taking it. I haven't tried it while in this aggitated state though. I have some left over so I'm gonna try it soon enough.
Acupuncture - Everyone seems to agree that acupuncture relaxes you. Lots of people claim it has many therapeutic effects too. From what I hear, you need to find a good acupuncturist, otherwise you're wasting your money. When I was having phenibut withdrawal I tried it, someone told me to go to this specific acupuncturist, shes a Chinese woman in her 50s so I'm guessing she has lots of experience.
Qi Gong - There is plenty of scientific evidence to suggest that qi gong has various healing effects. I was watching youtube videos last week and came across a video about "Falun Dafa" practitioners being persecuted by the police in China, they torture them to try and get them to renounce their belief but the practioners indure the torture rather than give up Falun Dafa (many of them have died in the process) so that got me fascinated. If these people rather endure weeks of torture than give up this practice, then there must be something to it. I started practicing it, there are 5 exercises, so far I've only learned the first one.
Meditation might work but its really hard to sit still and do it while aggitated like that. I'd say cannabis would work but for others but in my case it hits me like a psychedelic in a bad way (psychosis) and a dissociative so I can't function at all when I'm on it which is a bitch because in my experience, it cures all kinds of symptoms.
If you have experienced this symptom, can you share your experience on the things you've tried in order to remedy it. I'll list all the things I've tried so far.
THINGS THAT WORK:
DXM - This definitely works, it makes me extremely relaxed for about 4 hours and when it wears off I'm still relaxed, even the next day. The downside is its not something you can use regularly since tolerance builds up rapidly.
Exercising - I find that theres a certain threshold, you need to exercise heavily enough to reach this threshold then the agitation goes away, and doesn't come back for at least 30 minutes after I stop exercising. The best way to reach this threshold I've found is skipping. 10 minutes of skipping has me completely wrecked, I can't even do 10 minutes straight without taking small breaks yet.
THINGS THAT KIND OF WORK:
Amphetamine - Obviously this works since it releases dopamine but when it wears off, the restlessness comes back hard, making it impossible to sleep.
AMT - I get a similar effect to DXM while I'm on it, but when it starts wearing off the restlessness comes much worse. I tested it out yesterday and when it wore off I couldn't sit still.
Iboga - The most I've done so far is 8g of root bark, at that dose I barely get any psychedelic effects, instead I'm extremely relaxed and euphoric similar to AMT and DXM, but like AMT, I get extreme restlessness when it wears off. I'm gonna experiment with microdosing though.
Opiates - I've only tried codeine and DHC so far, they seem to help a bit but the akithisia is still there.
Gabapentin - Hit and miss. Sometimes it helps, sometimes it seems to amplify the akithisia. Gabapentin doesn't effect me in a normal way though, it effects me more like a stimulant than a sedative.
Trazodone - It kind of works. When I take it to sleep, the aggitation comes and goes the next day, then if I don't take trazodone the following nights, I get about 2 or 3 days with no restlessness before it comes back.
Benzos - They suppress the physical feeling of restlessness but the mental restlessness is still there. They're way too addictive to use as a daily remedy.
GHB/Phenibut - Hit and miss. I did phenibut daily for a few weeks and sometimes I would be completely relaxed, other times the akithisia was much worse than usual. The agitation would come on strongly the next day after doing phenibut. Also way too addictive to use as a regular remedy.
Nu-nu - Nu-nu is a snuff containing mapacho (nicotiana rustica, aka Indian tobacco) and mocambo bark (a tree closely related to coco). Snorting a bump of it seems to relax me initially but after about 20 minutes I end up more restless. I need to experiment more with this though, I've only tried it twice so far. I believe the relaxation is caused by nicotine, Indian tobacco contains up to 20 times as much nicotine as regular tobacco (nicotiana tabacum). I'm not a smoker so I don't know if smoking tobacco helps with akithisia.
THINGS THAT DIDNT WORK FOR ME
Picamilon, rhodiola rosea, magnesium (I've only tried oxide, I hear there are salts with much higher bioavailability), l-dopa (maybe I need to try a higher dose and I also want to try taking carbidopa with it which prevents it from being metabolised in the body before crossing the blood brain barrier), gotu kola, valerian root extract, l-theanine
MY LIST OF THINGS I WANNA TEST OUT
MAOIs - They should help by preventing dopamine from being broken down by MAO. I'm gonna try caapi tea first since I have it but selegiline sounds the most promising. I read that b. caapi has been proven to remedy Parkinsons disease symptoms, but the pharmaceutical companies couldn't figure out how to patent it so they moved onto other MAOIs.
Dopamine agonists - The only ones I know of are bromocriptine and apomorphine. AFAIK, bromocriptine is a selective D2 agonist which is prescribed for RLS. Apomorphine forms from decomposition of morphine and is a potent emetic. Its a non selective dopamine agonist, it binds to both D1 and D2 receptors.
Memantine - An NMDA antagonist with some D2 activity.
Kambo - Its venom from a species of Amazonian tree frog. It has lots of medicinal properties and in my experience, it makes you feel relaxed and good for the whole day after taking it. I haven't tried it while in this aggitated state though. I have some left over so I'm gonna try it soon enough.
Acupuncture - Everyone seems to agree that acupuncture relaxes you. Lots of people claim it has many therapeutic effects too. From what I hear, you need to find a good acupuncturist, otherwise you're wasting your money. When I was having phenibut withdrawal I tried it, someone told me to go to this specific acupuncturist, shes a Chinese woman in her 50s so I'm guessing she has lots of experience.
Qi Gong - There is plenty of scientific evidence to suggest that qi gong has various healing effects. I was watching youtube videos last week and came across a video about "Falun Dafa" practitioners being persecuted by the police in China, they torture them to try and get them to renounce their belief but the practioners indure the torture rather than give up Falun Dafa (many of them have died in the process) so that got me fascinated. If these people rather endure weeks of torture than give up this practice, then there must be something to it. I started practicing it, there are 5 exercises, so far I've only learned the first one.
Meditation might work but its really hard to sit still and do it while aggitated like that. I'd say cannabis would work but for others but in my case it hits me like a psychedelic in a bad way (psychosis) and a dissociative so I can't function at all when I'm on it which is a bitch because in my experience, it cures all kinds of symptoms.
