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  • BDD Moderators: Keif’ Richards

how long will the high from 75mg of avinza 510

deeb-0

Greenlighter
Joined
Feb 2, 2011
Messages
6
So i know when you google avinza it says 24 hrs but that's cause of those beads in the capsule so I emptied one full capsul and about 1/3 of another one she had left over. I crushed it all very fine and drank it about 45 mins ago now I feel great but I'm not a very heavy opiate user (I'm a weed n xanax guys myself) and I was wonder how long I should expect to feel good for?
 
Haha thank you very much its my first time on here so I'm learning n I felt dumb havin to ask you to clarify but since no one else has answered I guess I must what do you mean half life? So from one n a third of those ill only be high for 2 hours?
 
Half life is a term to describe how long it takes for half of the substance to decay. It comes about because of a logarithmic function (i.e. math). Basically if you take 100mg in two hours you'll have 50mg left in your body and in four hours you'll have 25mg left in your body. So in theory two hours after you "peak" on morphine you will be half as high.

That being said everyone's metabolism is different and everyone experiences the drugs differently so this is just a rough estimate.
 
Wow ok thank you very much! I'm so glad there's a place like this! Now on xanax after I peak I drink a few beers to boost me back up a bit, would that work with morphine too or would it just put me to sleep?
 
Xanax is a benzo which acts on the GABA neurotransmitter. Alcohol acts in a very similar manner and this is why you get a boost from it. In fact benzos are a treatment for acute withdrawal from alcohol for this very reason. Mixing benzos and alcohol is considered dangerous because they are such similar acting drugs and can combine to cause overdoses.

Opiates (morphine included) act on the brain in a different manner. Taking some booze with your opiates will not technically make you any higher on opiates like it makes you higher on benzos, however it will still act on its own (get you drunk) and may make you feel more off baseline; think complimentary instead of supplementary. Though arguably not as dangerous as alcohol and benzos, mixing any CNS depressant (booze included) with opiates (which depress your breathing) is also not exactly safe if you don't know your tolerances very well.
 
That makes a lot of sense. Again, thank you very much! I have never gotten such informative and complete answers about things of this nature. If you're not a doctor (which I'm sure you are) than you definitely missed your calling!
 
Haha you're welcome and I'm actually in engineering. I had to stop myself from going into a detailed explanation of the logarithmic equation of the half life of decaying radioactive isotopes though. Drugs are just very curious to me. Well actually all of nature is and drugs make you feel good. I've actually never taken benzos or morphine before though ironically.

edit:
you should make a intro thread in the New Member Introductions forum (NMI) if you want some more general chat :D
http://www.bluelight.ru/vb/forumdisplay.php?f=143
 
Yeah I saw you were trying to hold back some of that knowledge as to not confuse. That is ironic but at least if you ever try them you'll know exactly what you're doing. Though I would suggest benzos they make you more euphoric than just high without the horrible itching and economically they make more sense too. Yeah ill definitely have to do that this site is great but for now I'm off to see if cloud 9 is a queen or king size!
 
Oh I've done more than my far share of opiates=D ...just not morphine as it's bioavailability is so poor if not injected and I don't really want to start down that path, not that I'm particularly against it. I can definitely get by without benzos to relax as well.
 
Half life is a term to describe how long it takes for half of the substance to decay. It comes about because of a logarithmic function (i.e. math). Basically if you take 100mg in two hours you'll have 50mg left in your body and in four hours you'll have 25mg left in your body. So in theory two hours after you "peak" on morphine you will be half as high.

That being said everyone's metabolism is different and everyone experiences the drugs differently so this is just a rough estimate.

Like you said, the half-life of a drug can vary from person to person but it doesn't determine how long the drug will have a pharmacological effect on the body. and not bad for and engineer major! My roommate is an Nuclear Engineer, but he doesn't know much when it comes to pharmacology..ha
 
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Half life is blood plasma levels right? I just simplified by say they are correlated to how the drug feels. Like blood alcohol level. I can understand some drugs might trigger reactions which complete at their own pace or cross into the brain and hang our their for a few hours or something.

With all the discussion on metabolism of opiates in the liver I just assumed that their blood levels would be a good indicator of how you were feeling.
 
Avinza lasts about 8-12 hours. It doesn't last the entire 24 hours. I'm not sure of the sustained release mechanism that is used. I don't think it uses the same system that releases part of the dose when you first take it and another amount 4 hours later and another 4 hours another dose and so forth. Or maybe the dose is just gradually released.
 
Half life is blood plasma levels right? I just simplified by say they are correlated to how the drug feels. Like blood alcohol level. I can understand some drugs might trigger reactions which complete at their own pace or cross into the brain and hang our their for a few hours or something.

With all the discussion on metabolism of opiates in the liver I just assumed that their blood levels would be a good indicator of how you were feeling.

your right, t1/2 is how long it takes for half the drug to be eliminated from the blood plasma. and blood plasma concentration is correlated drug's effects are correlated, but not proportional.. Its not that big of a deal, since it complicates things way to much and it is simpler just to say wut u said.

Im trying to think of the name of the effect but it's a good example of this. When you drink alcohol, you will feel more drunk with a blood alcohol content (BAC) of .10 when your BAC is increasing than you will with a .10 BAC at the end of the night when your BAC is decreasing. It might help to think of your BAC as a curve /\.

So even at the same blood plasma level, you will get a different effect...

-cap
 
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