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How long before these psych meds are out of my system?

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flipkill?

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I'm on 450 of Wellbutrin, 10 of Lexapro, 0.5 of Risperdal for depression. I'd like to candy flip this weekend with some friends, so I skipped the Lexapro and Risperdal last night, and probably will tonight as well. Will this be enough time for the meds to be out of my system so they don't kill my flip? Thanks.
 
I don't think that is a long enough washout to not have your recreational effects significantly reduced. It isn't just about half-lives of the agents involved but also about things like down regulation of receptors. I don't know this for certain though. I admit I'm guessing more than speaking from experience though.

Also there are risks to discontinuing meds and depression might be worsened after the fact or even intrude on your planned enjoyment.

Anon---------------------->BDD
 
I'm on 450 of Wellbutrin, 10 of Lexapro, 0.5 of Risperdal for depression. I'd like to candy flip this weekend with some friends, so I skipped the Lexapro and Risperdal last night, and probably will tonight as well. Will this be enough time for the meds to be out of my system so they don't kill my flip? Thanks.

No offense intended, but I'm gonna go out on a limb here and say that if you've been diagnosed with a mental illness that is being treated with both antipsychotics and antidepressants, candy flipping is probably not in your best interest and neither is suddenly stopping any of your head meds.


EDIT: Actually, it's not my place to tell you what is or is not in your best interest, however, in the interest of harm reduction, suddenly stopping Risperdal (Risperidone) and/or Lexapro (Escitalopram) is a bad idea. Serious withdrawal symptoms, including zaps, vertigo and depression are associated with Lexapro in particular.
 
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^great advice all around. This might do better in Ecstasy Discussion but we can see what kind of response this gets here first... unless the BDD mods think it should be sent now, in which case, off ya go!
 
Drugs like Wellbutrin, Lexapro, and Risperdal take weeks before they began to take effect and it would be weeks before they are totally out of your system. They accumulate in your body over time (that's how they work). You can't just up and say "oh I think I won't take any this week so I can do this and that on the weekend".

It doesn't work like that.

Yes, I am going to send this to Ecstasy Discussion
 
I will answer your question to try and help out, but I'm sure we all know you're going to do it anyway. Respect your body, and especially your mind. Please. Don't take any MDMA and especially don't take the LSD. Or vice versa. They could both have equally negative after effects.

Here is the (not short) answer to your question:

Risperdal's HALFLIFE is 20 hours.
Wellbutrin HALFLIFE up to 30 hours depending on the type (SR, XR)
Lexapro HALFLIFE up to 32 hours

What that means: If you have taken XXXmg of something, above is the amount of time it takes for HALF that amount to be processed through the system. There are many many other factors to consider here, like how much is stored in your body already from regular use.

All of these drugs are generally not recommended to stop cold turkey. Meaning your body is used to them, meaning unpleasant side effects or withdrawals.

Long story short, since you want someone else to do the math for you I'm sure:

Risperdal's is for bipolar disorder and schizophrenia. DON'T quit it cold if you truly have these things. If you take MDMA with Risperdal in your system you're increasing risk of permanent Tardive Dyskinesia - Jaw Chatters, clenching. Not guaranteed, but not safe either. Assuming youve been taking Risperdal long enough for full saturation into your system, it will take 1-3 weeks for full detox depending on your lifestyle and metabolism. I'm guessing you're stationary a lot. Maybe a judgement call, but if you are, it will only take longer for things to dissipate in your system. However - MDMA + Antipsychotics + Depression are not a good idea.

Wellbutrin can effectively kill a roll without breaking a sweat. See above. Same advice here. Only difference, your kidney health greatly affects how fast this drug passes your system. 2-3 weeks for complete detox assuming you have been a regular consumer.

Lexapro is for anxiety and depression. 2-3 weeks detox assuming saturation. From what you are taking, I'm going to profile you and say the following:

You have abrubt mood shifts from anger to depression, and you "hate your life" and are extremely insecure and thus, the anxiety. I'm also going to assume your parent(s) had a lot to do with it because you won't find many people on those three drugs at an age older than 17. This is because about that time you've "had enough" because "no one understands you" and your problems "are because of someone else," not something that you can fix with medication.

So I'm going to say you're between 15 and 17, depressed, insecure, full of RX meds, and now you're planning on putting MDMA into your developing brain as well.

It's not a good idea. I believe you are going to do it anyway, but I am cynical and have no faith in people.

Best of luck to you. I hope your life turns around. No sarcasm intended. I truly wish you the best. Be safe bro!
 
You should absolutely not quit taking your meds without consulting a dr, especially with the amounts and type of drugs you're on. You will be in absolute hell if you stop cold turkey. And as others have said, they take weeks to leave your system completely. If you stop taking your meds you'll have a week of feeling like shit and then waste your money not getting high on the weekend. Bad idea.
 
how long before these psych meds are out of my system?

(This is flipkill could you please move to http://www.bluelight.ru/vb/showthread.php?t=570564 )

Just for the record, the 64 hours or so was enough time to get enough of the meds out of my system that I didn't notice any dampening of effects. Also, no W/D symptoms.

No offense intended, but I'm gonna go out on a limb here and say that if you've been diagnosed with a mental illness that is being treated with both antipsychotics and antidepressants, candy flipping is probably not in your best interest and neither is suddenly stopping any of your head meds.

None taken. I agree, none of this is the safest thing I could be doing, but I've done it enough times that I don't expect anything catastrophic to happen. I'll probably feel a little more depressed on Tuesday or so from blowing out my serotonin, but that will also pass.

Also, for the record, just because someone is being treated with antipsychotics doesn't mean that they are (or ever have been) psychotic. For that matter, a lot of people who aren't depressed take antidepressants for other reasons.

Risperdal's is for bipolar disorder and schizophrenia. DON'T quit it cold if you truly have these things. If you take MDMA with Risperdal in your system you're increasing risk of permanent Tardive Dyskinesia - Jaw Chatters, clenching.

My diagnosis is 296.33, Major Depressive Disorder, Recurrent, Severe Without Psychotic Features. I've never been psychotic, but I've had a lot of annoying side effects from first line antidepressants, so we're working with second and third line treatment options.

I've been diagnosed by multiple doctors, both bipolar and schizophrenia have been ruled out. Do you have any more info about increased possibility of TD from MDMA/Risperdal? I'd like to learn more.

Ha, I actually did the half life math as well. I think that I had about 53% of peak plasma level of Lexapro after 64 hours, and about 16% of the Risperdal.

Wellbutrin can effectively kill a roll without breaking a sweat.

I know this is very true for SSRIs, but never had any problems with Wellbutrin killing a roll. I think that Wellbutrin is a noradrenaline reuptake inhibitor (NARI), and works on dopamine, serotonin, and norepinephrine, but far and away the biggest effect is on dopamine.

Just found this out, which is mildly interesting: "WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines."

You have abrubt mood shifts from anger to depression, and you "hate your life" and are extremely insecure and thus, the anxiety. I'm also going to assume your parent(s) had a lot to do with it because you won't find many people on those three drugs at an age older than 17. This is because about that time you've "had enough" because "no one understands you" and your problems "are because of someone else," not something that you can fix with medication.

So I'm going to say you're between 15 and 17, depressed, insecure, full of RX meds, and now you're planning on putting MDMA into your developing brain as well.

That would probably be my assumption as well if I were in your shoes. This something I do once or twice a year with friends, not an every weekend rave thing. I'm actually in my 30s, went through both undergrad and grad school, don't live with my parents, have a good job and my own place. I've been dealing with depression for most of my life, it just waxes and wanes.

I did have some mini-breakthroughs last night, and I think the deeper understanding I gained will be helpful enough in the medium to long term to outweigh any short term negative effects I might have.

Thanks, I really do appreciate all of your input.
 
I officially take a knee to your response. I prematurely judged you, and for that I apologize.

I will gladly get you the TD info, you're a guest so I'll just post it here. Give me a bit.

If the side effects have been a clouded, spaced feeling, or the inability to think, adding additional meds isn't the best route IMHO. If they're sexual side effects, or impulsive thoughts and desires (futile feelings, desire to drive fast, basic over the top feelings etc) you probably need a lower dose or different med.

For example, effexor can make the world seem sterile and dry. Not depressed, but not "right." Wellbutrin is known to cause crazy hallucinations at high and low doses in some people... I could go on, but it also sounds like you've been working through a few.

I commend you on your fight. True deep depression is a nightmare when it comes in waves. If you haven't had a rough past, or PTSD from trauma and it's just a chemical imbalance, that can be worse than trauma-rooted depression. I have worked with lots of people who have had more problems from the prescribed meds than the problem itself.

I'll get the info and post it. Just be safe man. I love MDMA. I'm just cautious about how I use it.
 
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