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Misc How come (short)sleep ruins high/buzz

T

TTZ234

Bluelighter
Joined
Mar 12, 2004
Messages
115
Location
Bergen,Norway( US born/double citizenships)
Im sure Im not alone in having taken a long acting opioid or a bunch of benzos,fallen asleep unintentionally for 2-4(or even 1) hours then woken up feeling completely sober..
Anyone know why this is..Ive looked all over the web for an answer to this ,but always come up short..
 
Perhaps you're still high when you wake up and you just don't notice the difference from sobriety. Benzodiazepines especially can have a very subtle effect.

You could also have a tolerance for opiates/benzos.
 
telling us exactly what you took and your tolerance would help us determine whats going on but it sounds like you might be using a short/medium acting opiate and have become tolerant to it. if you want to optimize your opiates and find it hard to stay awake and enjoy them you might want to cut the benzos. although after rereading you post you may want to ask a clearer question. good luck.
 
Yeah I reckon I have a tolerance at this point..what I was referring to in my case here was ca 50mg of methadone(following 40mg the day before,used recreationally..or that is outside a MMT program) + a couple of klonopin and a couple of Xanax..fell asleep for about 2 hours and when I woke although the half life of these drugs should make me feel still high..this is one case though..this happens every time I fall to sleep prematurely almost ..
I framed my question on a general level cause I understand sleep have a diminishing effect on other peoples high as well,and have always wondered during sleep the body produces some kind of natural antagonist to the effects of sedative/opioid drugs or if maybe the endogenous chemical that wakes you up have such qualities..

Thanks for answering btw:)
 
TTZ234 said:
and have always wondered during sleep the body produces some kind of natural antagonist to the effects of sedative/opioid drugs or if maybe the endogenous chemical that wakes you up have such qualities.
Click to expand...

No, definitely not - especially with an opioid like Methadone whose effects can last from 12-24 hours in most people. My thoughts are along the same lines as others' - that you have built a tolerance to the Methadone. I've passed out cold from 40mg of Methadone with little/no tolerance and woken up 12 hours later high as a kite. Though I've noticed the more I focus on what I should be feeling ("trying" to feel high, you might say), I have little success. But the moment I occupy myself with something like surfing the web, reading a book, or watching television I begin to nod out like nobody's business.

The only time I have experienced what you say you have experienced is when I take an opiate whose half life I've slept through. For example, if I take 50mg of oxycodone and fall asleep for 4-6 hours, I wake up at near baseline.

It's been so long since I've been non-tolerant to benzodiazepines (about 10 years now) that I can't really comment on that one. If you are scripted them, though, it wouldn't surprise me the least if the effects had virtually disappeared after a couple hours' sleep, no matter the benzo (i.e. the same would happen, IME and with a tolerance, using alprazolam [half-life ~6-11 hours] vs. diazepam [half-life ~20-100 hours]).

Hope this helps. Try to reduce the amount/frequency of opiates and/or benzos that you consume.

~ vaya
 
Well with benzos no matter the half-life your mind is likely just assuming you're 'regular'/sober as you wake up, and the mind is also doing it's other wake-up routines (melatonin regulation etc).

Also, it's easy to forget you're still close to peak plasma on long half-life benzos 8-10 hours into the high. What I'm saying is even with ~20-60hour half-life benzos, you still have high levels in the brain up to 10 hours in... easily. So you get 'used' to it.

One could even go as far as saying 'sober' is simply a high we're used to... because 'sober' is the sum of all the 'natural' (brain-synthesized) drug activity in your brain. Sorry, it's early and I am having a problem articulating correctly. You get the jist.
 
Its the same for me, if I pass out pretty much high on anything I will wake up pretty sober, even if I only sleep for an hour or so.
 
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