Help needed with bad NBome reaction

[G'dink!]

Hi everyone,

A few days ago I took about 2000 mcg of nbome (25-i), which is the highest dose I’ve ever taken. (I took about 1800 mcg the week before, which was completely fine, but it means that I probably had a slight tolerance when I took 2000). I always find the come up really rough, and usually have to throw up in order to feel better, but this time was a lot worse than usual: I felt really, really sick, and spent about an hour retching but wasn’t really able to throw up (sorry about the gross details…). I also felt like I had something stuck in my throat and I could feel it every time I was breathing in. I don’t think there was actually something in my throat, but I was really high and it felt real at that time. I could still breathe ok, but it was a very disturbing feeling.
Another weird thing happened as well: about a week before, I was badly bitten by midges and my face, neck, chest and arms were covered in bites. They had almost disappeared when I tripped, but as I was coming up, all the bites on my face and neck became bright red / dark red, almost purple (the ones on my arms and chest weren't affected). I have to admit I freaked out at that point when I saw my face covered in red spots...
I ended up taking an etizolam about 2 and a half hours after dropping, which sobered me up pretty quickly and really helped with my stomach and my throat. I stayed up with my friends for a while and went to bed about 8 hours after taking the etizolam. When I woke up the next day, I felt normal again. The bites are still here now (3 days later), and although they seem to be getting slightly better, they are still red and very much visible.
I feel completely normal now, so I don’t think it was really serious, but I would still like to know if anyone has ever heard of something similar, or knows why my bites became so red all of a sudden. My friends told me it was probably because I spent an hour retching and trying to throw up, but surely, if that was it, they wouldn’t be as red three days later, would they? Could all this have happened because my body can't handle such a high dose of nbome?
One last question: my boyfriend and I were planning on taking acid this weekend (so that would be 5 or 6 days after the nbome incident), but we’re not sure it’s safe anymore. What do you think?

Thank you for taking the time to read this!

 

[lamanogaucha]

Regarding your last question, you should wait a minimum of two weeks, as NBOMe (and related) compounds cause very significant tolerance; if you take the LSD earlier, you may not experience its full impact. As far as safety is concerned, you should be OK, but be vigilant.

 

[kush fario]

Im not sure could have something to do with the way the nbomes effect the blood im sure youl be fine but tripping this weekend could be a waste and giving it another week wont do anything bad to your body

 

[G'dink!]

Thank you both for your replies. According to what I’ve read and what I’ve been told, tolerance can vary a lot and everyone isn’t affected in the same way. I took 2000 mcg of 25-I because I had taken about 1800 the week before and thought the tolerance would make it weaker, but I don’t think it actually did. I was a lot higher than the week before. My boyfriend did LSD that night even though he had done 25-I the week before, and he didn’t seem to have a tolerance at all either. But I guess these 2 occasions don’t necessarily mean that we won’t have a tolerance next time. Anyway, you’re both right, having a break can’t be a bad thing. Just to be clear, we don’t trip that frequently all year round! We’ve done it a few times over the past month because we both had more time off work than usual, but we usually don’t do it more than once every couple of months, and we were planning on having a long break after that LSD trip anyway! I don’t think I’m going to take nbome for a little while anyway, and when I do, I’ll start with really small doses again, and will progressively work my way up to about 1200, but I doubt I’ll ever take more than that again.

Thank you again! If anyone else has an idea of what could have happened, I’m all ears

 

[reflux21]

You took too much, simple as that.

 

[.:Holy::Toast:.]

The way NBOMe's and psyches in general affect blood flow can do some weird things, I've had pale cold hands and feet numerous times from vasoconstriction, perhaps it restricted blood flow from your extremities in the same way and redirected it to your head/core, causing flushing and re inflammation
NBOMe's iirc are notorious for causing vasodilation, especially in the very high doses such as what you took

 

[G'dink!]

Yeah, I did think I probably had a bit too much, but I was curious to hear people’s opinions because I didn’t have the symptoms people usually get when they take too much nbome. I knew about vasoconstriction but my skin didn’t turn paler (quite the opposite), I didn’t get pins and needles in my hands/legs, etc… What you say about blood flow makes sense anyway, thank you!

 

[HazelCloud]

Yeah, I did think I probably had a bit too much, but I was curious to hear people’s opinions because I didn’t have the symptoms people usually get when they take too much nbome. I knew about vasoconstriction but my skin didn’t turn paler (quite the opposite), I didn’t get pins and needles in my hands/legs, etc… What you say about blood flow makes sense anyway, thank you!

2mg-3mg is what I would consider a mild overdose. Based on past experience, anything over 1.5mg is extremely hard to control. Your reaction was most likely an unrealistic distortion of worry for the bug bites(strange things like this can easily happen on high dose psychedelics). With a tolerance, I was once able to control 2 tabs of 25C-NBOMe (1.2mg) which is roughly equivalent effects-wise to 2mg 25I. I enjoyed it, but not without the occasional frightening thought or objects morphing completely into other objects. It was scary, but fun at the time. Next time go 1.5mg or under IMO.

 

[25I_am_so_wonderfu]

I don't understand why people are even interested in taking this chemical with how much harm and death this class of chemicals have caused in the short time since it has gone commercial. Not to mentions those who've had reactions because they thought were taking LSD instead.

 

[Solipsis]

I agree you just shouldn't take so much, and as for the bites getting red (for a moment I thought you said 'midgets'), it may be possible for these compounds to have some sort of immunological effects which is also sometimes seen with 2C-B and other 2C-X... or at least things like overproduction of mucus have been observed. I don't think it is understood very well.

 

[thizzkid]

That is a lot of NBOMe; thats the plain answer. I think youre probably over-speculating the bug bites, but that is strange no doubt.
I would have an extremely strong trip if I were to take 2mg, I have a report I posted on BL of my friend who had a mental breakdown on only 1000ug of 25b-NBOMe and he is a bigger-built male, so what youve experienced is entirely expected. I would honestly lower your doses. 1.5 mg is really all an experienced tripper needs fro a powerful trip.
As far as the tolerance question goes, no psychedelic that I've ever taken has had more significant and long-lasting cross tolerance than the NBOMes. I would wait at least 2 weeks, probably 3 if you want the LSD to have its full effects.
Have fun and stay safe!

 

[G'dink!]

I’m quite surprised to see everyone thinks it’s an incredibly high dose… One of my friends usually takes 4000mcg to start with and then tops up with another 2000. Another friend (a girl) always starts with 3000. And these doses work well for them. They end up having relatively strong trips, but are still fully capable of talking, walking, eating, and functioning normally, so these dosages aren’t too high for them.
I’ve been very careful and have always worked up very progressively just so I’d know when to stop. All my trips have been completely fine, including the one when I had 1800mcg, which is almost as much as 2000. I actually spent the whole day walking around a forest, so it wasn’t that strong a trip! And 2000 would have been completely fine in terms of strength. I was really high but could still walk around, talk, and think clearly. I think safe dosages are different for everyone. I’ve probably reached mine, so now I know not to take that much in the future, but I think it varies according to people. In reference to your friend who had a mental breakdown after taking 1000mcg, I’ve taken this dose myself and it did barely anything to me… (I have tried this dosage on more than one occasion with 25i from various sources, all giving consistent results.)
The bug bites are all gone now anyway, and everything is fine!

 

[kidklmx]

People have died from such dosages, so the replies are to be expected. If you're absolutely sure that the dosages are safe for you or your friends that is fine and well, but you shouldn't really be posting that on a public forum.

 

[psynami]

Kidklmx do you have any links with info about the people that died with these dosages? I thought it was mostly really really high dosages because they were taking powder. So they were taking dosages like 40 mg or something along those lines.

 

[Deleted member 290563]

YOu're overdosing....you just doing think so because your 5-HT tolerance is so high that you don't trip... but that doesn't mean the drug isn't taking a toll on your body just because you "aren't high" you're taking way too much and so are your friends.....if you are doing that 2-4 mg to trip hard enough you're doing it too often, 500ug to 1mg should be enough for a strong trip if you are dosing your self the right way

 

[kidklmx]

No exact dosages I'm afraid, but hopefully this page will be enough for you to be more careful? Was talking more about your friend btw, 2mg is not exactly conservative in any way (personally, I wouldn't go above 1.2mg because of vasoconstriction) but it has been safe for some

 

[G'dink!]

I was going to ask the same question as Psynami, because I’ve read many reports, but I’ve never seen anything regarding death caused by 2mg, or even 4mg, so I was quite surprised when you wrote people had died 'from such dosages’. I had already read the reports you’ve sent, and most of them indicate that the people who died either had a lot because they thought it was something else (generally LSD), because they took it with something else, or because they didn’t actually know how much they were taking.

I personally would never take as much as my friends, not in a million years: my plan was to take a tiny bit more every time I did nbome and to stop at the slightest sign of vasoconstriction (which never happened). My friends are doing the same, and so far they've never had any sign of vasoconstriction either. I’m not responsible for the doses they take, but I will make sure they read this thread before they do it again, even though they’ve already read a lot about nbome and know the risks they’re taking.

May I also ask why I shouldn't be posting that on a public forum? I thought the forums’ purpose was to provide as much information as possible in order to reduce harm, so if some people were considering taking such high doses and have read everyone’s comments, they will now think twice before they do it, which surely is a good thing.

 

[atara]

It sounds like you had a mild allergic reaction, probably to the midge bites, albeit incited by the drug. Psychedelics affect the immune system; 5-ht2a activation suppresses TNF-alpha production. Of course, normally this would be anti-inflammatory, but in this case perhaps your body, trying to maintain homeostasis, responded by increasing immune system activity some other way.

I wouldn't take any more psychedelics until the bites have totally disappeared. Also as a general rule you should consider dialing down the psychedelic usage if tolerance is becoming an issue, especially at such high doses (2000 mcg!!).

The huge doses of 25I-NBOMe you're taking tell me that you might not be using the best route of administration. A disadvantage of this is that sometimes the drug will be much more effectively absorbed, giving you a stronger dose than you expected. You might want to try some other way of taking it, usually drops in the nose are pretty reliable, and if you do this you will definitely need to take smaller doses, but they should be more consistent effect-wise.

Unpredictable bioavailability can lead to overdose if it is suddenly much higher than expected. 25x drugs [we think] activate 5-ht2b [LSD does not] potentially causing pulmonary vasoconstriction, which is to be distinguished from peripheral "cold feet" vasoconstriction. Some people are simply more at risk for heart problems than others; those people are more likely to have serious complications from high doses of 25X drugs. Without knowing a whole lot about your medical history our only serious recommendation is not to use very much of the drug, good advice in any case, and yes people have died from heart attacks while on several milligrams of 25X. Repeated use of 5-ht2b agonists (fenfluramine) is associated with cardiac defects (valvulopathy).

 

[G'dink!]

I wouldn't take any more psychedelics until the bites have totally disappeared. Also as a general rule you should consider dialing down the psychedelic usage if tolerance is becoming an issue, especially at such high doses (2000 mcg!!).

All the bites have gone now, thankfully!
I don’t usually take drugs so frequently. As I wrote in a previous post, I took 25i twice last month because me and my friends had more time off work than usual, but it was a one-off, and we usually don’t have that many opportunities to do it. We always wait quite a while between every experience, and I was planning on having a really long break after that anyway to make up for the fact that I did it more than once within such a short period of time.

The huge doses of 25I-NBOMe you're taking tell me that you might not be using the best route of administration. A disadvantage of this is that sometimes the drug will be much more effectively absorbed, giving you a stronger dose than you expected. You might want to try some other way of taking it, usually drops in the nose are pretty reliable, and if you do this you will definitely need to take smaller doses, but they should be more consistent effect-wise.

The stuff we have is in tab forms, but I will look into those drops you mentioned, thank you!

Without knowing a whole lot about your medical history our only serious recommendation is not to use very much of the drug, good advice in any case, and yes people have died from heart attacks while on several milligrams of 25X.

I don’t think I’m going to be experiencing much more with nbome to be honest. I got pretty scared the other day, and I think I’m going to stick to drugs which have been around for longer and are known to be safer. Would you be able to send me the reports which mention the people who died from such doses? I’d be very interested in reading them.
Thank you for all these information anyway, they were very helpful!