The shortened half-life referred to in the medical studies and medication handouts (mean 2.2 hours) refers to doses under 2 mg., mostly doses in the mcg. range. This is different because there is not enough bupe in that small of a dose to fully saturate the receptors like there is in doses above the mcg. range. In doses greater than 1-2 mg., the half life remains the same whether it's 2 mg. or 16 mgs. There is enough bupe in doses that high to fully saturate the receptor sites and block opiates from being able to bind. Plus, when discussing Suboxone as opposed to Subutex, there is also the factor of Naloxone to consider on top of the Bupe.
So, to sum it up, in doses above 2 mgs., regardless of ROA, the half-life remains the same....approx. 37 hours. That means if one dosed 2 mg, no matter ROA, the amount of bupe/Naloxone still active in the body 37 hours later would be 1mg. Bupe/.5 mgs. of Naloxone. Remember, that is REGARDLESS of ROA.
I'm sorry to come off sounding condescending but I have seen this question so many times and have YET to see anyone answer it correctly. I'm also sorry for reviving an old thread but in the interest of harm reduction, I felt it was necessary for anyone else who came across this thread to have the correct information instead of just shooting bag after bag and having the H not work, a waste of money, but also possibly overdose from the respiratory depressant qualities of the drugs while trying to achieve the high they are looking for. Save your dope man, it's a waste of money to even bother until at least the 24 hour mark. 36 is better but I have seen someone catch a good rush after only 18 hours. Even then it took a higher dose than normal.
Your mileage may vary slightly, but only VERY slightly. Please be safe and play smart.