Gamma-Hydroxybutyric acid
(Common: NaGHB, MgGHB, CaGHB, KGHB)
(Sodium is most common.)
I. Basics
II. Verbal Summary
III. Lethality
IV. Long term Physiological Health Risks
V. Detection
VI. Terms
I. Basics
Street Names: GHB, G, Georgia Homeboy, Liquid Ecstasy, Water, (Typically any name with "G" emphasized at the beginning like Gina.)
Pharmaceutical: Xyrem (Sodium Oxybate) owned by, Jazz Pharmaceuticals
Classification: Depressant(70/100), Stimulant (20/100), Dissociative(10/100)[Ratios made based on author's opinion.]
Recreational Dose: .5g-2g
Medicinal Dose: 4.5g
Estimated lasting time: 2-6hours (Average around 2 1/2 to 3 hours.)
Half Life: 30 minutes to 1 hour.
Toxic Metabolites: No.
Addiction Potential: Medium
Precursor Prodrug: Gammabutyrolactone
Street Names: GBL, Lactone, Lac
Use: Industrial Solvent, also a psychoactive drug.
Doseage: .5 - 1.5g
Medicinal Dose: None
Lasting time: Slightly less than GHB
Toxic metabolites: Yes.
II. Verbal Summary: GHB is a powerful CNS depressant drug in which targets both GABA-B and the GHB receptor. It is created by the body naturally and is difficult to detect as it clears from urine tests very fast. (No longer than 24-hours)
GHB has a steep dosing curve in which implies its recreational dose and overdose are tied closely together. GHB overdose results in a rapid, uncontrollable loss of consciousness in which anti-drug campaigns used to coin it as a date-rape drug. However, it is best described as Liquid Ecstasy as it is possibly the most euphoric of the GABA-ergic drug family.
Because of its difficulty dosing, drug abusers are forced to stick to a single doseage(Far from a lethal dose) rather than rapidly chase a high. GHB has dozens of medicinal uses. Its effects are closest to alcohol or barbiturates, however its mind altering effects on cognition and memory are arguably, substantially less.
III. Lethality
GHB's individual Lethal dose is unknown as GHB helps transport and store oxygen to organs even in cases of deep respiratory depression. It is often said by experts that many of the GHB-death horror stories are either myths or the result of a poly-drug overdose. GHB overdose is fairly easy to fall into and even though lethal doses are very far from an overdose, unconsciousness can result in asphyxiation from vomiting or bad positioning. If you suspect a person has swallowed a lethal dose of GHB: has dangerously slow, shallow breathing, a slow pulse and cannot be awoken, call 9-11 immediately. If the person has consumed any Depressant: GABA-ergic (Alcohol, Benzos, Barbiturates, Z-drugs) or Opiates then they are at a great risk of cardio-respiratory arrest and death. Only an idiot would consume another depressant with GHB.
IV. Long-Term Physiological Health Risks
Addiction is the largest health risk in association with GHB use among healthy young adults. Its short half life and euphoric effects become compulsive and without the side effects of alcohol, it can be deceptively easy to use for months. Abuse of its sodium base can result in an off-set of electrolyte levels which can result in weakening of the heart, increased blood pressure, tatchycardia and kidney damage (Due to dangerously high daily sodium intake). It is best to make sure to take potassium, magnesium and drink plenty of water while using NaGHB(Salty).
V. Detection
GHB is a clear oily liquid with a mild chemical smell. It is most often EXTREMELY salty in taste and can be repulsive to most people. GHB is carried in bottles and nearly impossible to differentiate from water unless shaken (Revealing its different viscosity). If your drink has been left unwatched and once re-consumed, tastes saltier than normal, find a friend to watch after you and leave the setting. Fortunately the amount needed to "Date rape" someone is high enough to easily detect based on taste alone.
A) Use Detection (DO NOT GET IN THE CAR OF A GHB INTOXICATED DRIVER.) (This is intended to save people from G-intoxicated drivers. Unconsciousness at the wheel will result in a wreck.)
GHB use can vary wildly. The easiest sign of use is a sudden loss of consciousness as the person reaches a comfortable position, followed by coming awake acting completely sober with no smell of alcohol and deceptively normal behavior.
As it has a short half life with both stimulant and depressant effects, detection is extremely difficult, if not impossible in some cases. If the user shows no symptoms of use for 30-45 minutes since first confronted, it is probably best to trust them. Most drug tests do not test for GHB as after about 6 hours it becomes negligible if the amount found in blood is natural.
Novice Detection:
Goofiness, giggly attitude, ecstasy-like behavior, slow speech, drinking liquid from a bottle cap rather than the bottle, Uncoordinated movements with a deceptively normal thought process.
Higher levels of detection:
Horizontal gaze Nyzagmus, Teetering in a standing position, Relaxed facial muscles, Uncontrollable laughter, Short term memory loss, Confusion, Slurred speech, Excited-Euphoric behavior without muscular contractions similar to stimulants, Random contractions of ligaments(wiggling fingers, toes, relaxed fidgeting.).
Nyzagmus and facial muscle relaxation is probably the fastest way to detect use. High doses of GHB can be similar to the "eye wiggles" of ecstasy in which the user goes cross-eyed.
Case scenario where GHB use is a high probability:
HGN
Stumbling, uncoordinated movements
Drunk behavior with clearer memory, more energy and better capability of speech
No smell of alcohol
Falling asleep and becoming conscious with a burst of energy
Drinking from a bottle cap
Goofiness
Mood swings every 2 hours. Usually either from relaxed to paranoid or relaxed to irritable.
VI. Terms
Cap: A single hit of GHB. Typically a 6-ml bottle cap. Approx. 1.5g. Stronger concentrations exist, but GHB is not always something you want to have to dose with a calibrated oral syringe...
G-ing out, G-Hole or Carp: The state of overdosing on G and falling asleep uncontrollably. Ex: "Dude I was at my friends house and I couldn't feel the G so I took another cap and started feeling tired. I sat down and suddenly woke up 3 hours later. I totally carped out."
G-Tard: Someone who really really likes GHB.
Dopamine Rebound: The effect that happens after exogenous GHB begins to finish its metabolization and is in lower concentrations, thus activating its stimulant effects. Dopamine rebound is a reversal of dopamine inhibition into dopamine release, which can be either enjoyable or unpleasant depending on how long it has been used, the dose and if a stimulant is present. Dopamine rebound can cause a heightening of blood pressure and tatchycardia as well as irritability and anxiety.
(...To be Continued)
(Common: NaGHB, MgGHB, CaGHB, KGHB)
(Sodium is most common.)
I. Basics
II. Verbal Summary
III. Lethality
IV. Long term Physiological Health Risks
V. Detection
VI. Terms
I. Basics
Street Names: GHB, G, Georgia Homeboy, Liquid Ecstasy, Water, (Typically any name with "G" emphasized at the beginning like Gina.)
Pharmaceutical: Xyrem (Sodium Oxybate) owned by, Jazz Pharmaceuticals
Classification: Depressant(70/100), Stimulant (20/100), Dissociative(10/100)[Ratios made based on author's opinion.]
Recreational Dose: .5g-2g
Medicinal Dose: 4.5g
Estimated lasting time: 2-6hours (Average around 2 1/2 to 3 hours.)
Half Life: 30 minutes to 1 hour.
Toxic Metabolites: No.
Addiction Potential: Medium
Precursor Prodrug: Gammabutyrolactone
Street Names: GBL, Lactone, Lac
Use: Industrial Solvent, also a psychoactive drug.
Doseage: .5 - 1.5g
Medicinal Dose: None
Lasting time: Slightly less than GHB
Toxic metabolites: Yes.
II. Verbal Summary: GHB is a powerful CNS depressant drug in which targets both GABA-B and the GHB receptor. It is created by the body naturally and is difficult to detect as it clears from urine tests very fast. (No longer than 24-hours)
GHB has a steep dosing curve in which implies its recreational dose and overdose are tied closely together. GHB overdose results in a rapid, uncontrollable loss of consciousness in which anti-drug campaigns used to coin it as a date-rape drug. However, it is best described as Liquid Ecstasy as it is possibly the most euphoric of the GABA-ergic drug family.
Because of its difficulty dosing, drug abusers are forced to stick to a single doseage(Far from a lethal dose) rather than rapidly chase a high. GHB has dozens of medicinal uses. Its effects are closest to alcohol or barbiturates, however its mind altering effects on cognition and memory are arguably, substantially less.
III. Lethality
GHB's individual Lethal dose is unknown as GHB helps transport and store oxygen to organs even in cases of deep respiratory depression. It is often said by experts that many of the GHB-death horror stories are either myths or the result of a poly-drug overdose. GHB overdose is fairly easy to fall into and even though lethal doses are very far from an overdose, unconsciousness can result in asphyxiation from vomiting or bad positioning. If you suspect a person has swallowed a lethal dose of GHB: has dangerously slow, shallow breathing, a slow pulse and cannot be awoken, call 9-11 immediately. If the person has consumed any Depressant: GABA-ergic (Alcohol, Benzos, Barbiturates, Z-drugs) or Opiates then they are at a great risk of cardio-respiratory arrest and death. Only an idiot would consume another depressant with GHB.
IV. Long-Term Physiological Health Risks
Addiction is the largest health risk in association with GHB use among healthy young adults. Its short half life and euphoric effects become compulsive and without the side effects of alcohol, it can be deceptively easy to use for months. Abuse of its sodium base can result in an off-set of electrolyte levels which can result in weakening of the heart, increased blood pressure, tatchycardia and kidney damage (Due to dangerously high daily sodium intake). It is best to make sure to take potassium, magnesium and drink plenty of water while using NaGHB(Salty).
V. Detection
GHB is a clear oily liquid with a mild chemical smell. It is most often EXTREMELY salty in taste and can be repulsive to most people. GHB is carried in bottles and nearly impossible to differentiate from water unless shaken (Revealing its different viscosity). If your drink has been left unwatched and once re-consumed, tastes saltier than normal, find a friend to watch after you and leave the setting. Fortunately the amount needed to "Date rape" someone is high enough to easily detect based on taste alone.
A) Use Detection (DO NOT GET IN THE CAR OF A GHB INTOXICATED DRIVER.) (This is intended to save people from G-intoxicated drivers. Unconsciousness at the wheel will result in a wreck.)
GHB use can vary wildly. The easiest sign of use is a sudden loss of consciousness as the person reaches a comfortable position, followed by coming awake acting completely sober with no smell of alcohol and deceptively normal behavior.
As it has a short half life with both stimulant and depressant effects, detection is extremely difficult, if not impossible in some cases. If the user shows no symptoms of use for 30-45 minutes since first confronted, it is probably best to trust them. Most drug tests do not test for GHB as after about 6 hours it becomes negligible if the amount found in blood is natural.
Novice Detection:
Goofiness, giggly attitude, ecstasy-like behavior, slow speech, drinking liquid from a bottle cap rather than the bottle, Uncoordinated movements with a deceptively normal thought process.
Higher levels of detection:
Horizontal gaze Nyzagmus, Teetering in a standing position, Relaxed facial muscles, Uncontrollable laughter, Short term memory loss, Confusion, Slurred speech, Excited-Euphoric behavior without muscular contractions similar to stimulants, Random contractions of ligaments(wiggling fingers, toes, relaxed fidgeting.).
Nyzagmus and facial muscle relaxation is probably the fastest way to detect use. High doses of GHB can be similar to the "eye wiggles" of ecstasy in which the user goes cross-eyed.
Case scenario where GHB use is a high probability:
HGN
Stumbling, uncoordinated movements
Drunk behavior with clearer memory, more energy and better capability of speech
No smell of alcohol
Falling asleep and becoming conscious with a burst of energy
Drinking from a bottle cap
Goofiness
Mood swings every 2 hours. Usually either from relaxed to paranoid or relaxed to irritable.
VI. Terms
Cap: A single hit of GHB. Typically a 6-ml bottle cap. Approx. 1.5g. Stronger concentrations exist, but GHB is not always something you want to have to dose with a calibrated oral syringe...
G-ing out, G-Hole or Carp: The state of overdosing on G and falling asleep uncontrollably. Ex: "Dude I was at my friends house and I couldn't feel the G so I took another cap and started feeling tired. I sat down and suddenly woke up 3 hours later. I totally carped out."
G-Tard: Someone who really really likes GHB.
Dopamine Rebound: The effect that happens after exogenous GHB begins to finish its metabolization and is in lower concentrations, thus activating its stimulant effects. Dopamine rebound is a reversal of dopamine inhibition into dopamine release, which can be either enjoyable or unpleasant depending on how long it has been used, the dose and if a stimulant is present. Dopamine rebound can cause a heightening of blood pressure and tatchycardia as well as irritability and anxiety.
(...To be Continued)
