Stimulants Focalin vs. Vyvanse

[jfischer218]

Im getting both tomorrow, im just curious what I can expect. I used to love adderall and its the only stim ive ever done besides coke/rock. Basically my questions are:

1)What are comparable dosages? Im planning to try 50 mg vyvanse, which seems like a good starting dose. How many mgs of focalin would be needed for a comparable high in focalins respect?

2)ive read that people like vyvanse better because focalin tends to make them angry/uncomfortable. Is focalin generally bad or is it still better than a cup of coffee but worse than amphetamine? (I know ill probably get mixed responses, im looking foreward to hear peoples reasoning)

3)After a 50 mg dose of vyvanse and no tolerance to amphetamines, will my pupils be dilated at all throughout the day or during/after the comedown?

Thanks for the help guys

 

[pasha]

1)What are comparable dosages? Im planning to try 50 mg vyvanse, which seems like a good starting dose. How many mgs of focalin would be needed for a comparable high in focalins respect?

It's difficult to determine equipotent dosages from methylphenidate (structurally identical to dexmethylphenidate or focalin) to lisdexamfetamine but here's what I've been able to find:

Methylphenidate 72 mg = approx. Vyvanse 50 mg

2)ive read that people like vyvanse better because focalin tends to make them angry/uncomfortable. Is focalin generally bad or is it still better than a cup of coffee but worse than amphetamine? (I know ill probably get mixed responses, im looking foreward to hear peoples reasoning)

Methylphenidate users who have tried both tend to agree that amphetamines are superior in every respect (attention, memory, concentration). Methylphenidate seems to fall short in every department when it comes to cognition. Even from a pharmacological stand point (although they work differently) both operate on dopamine and norepinephrine, with amphetamines being much more potent dopamine/norepinephrine releasers.

In terms of side-effects profile, users of methylphenidate compare it to cheap cocaine, or as a dirty feeling, were as amphetamines are much more polished and clean.

3)After a 50 mg dose of vyvanse and no tolerance to amphetamines, will my pupils be dilated at all throughout the day or during/after the comedown?

As long as the drug is active your pupils will be dilated.

 

[AlphaMethylPhenyl]

I found my pupil size to decrease while on amphetamine - weird. During the come-down they got big, though. Not to hijack but anyone know why this was?

 

[jfischer218]

Chromophobe, you answered my question perfectly; thank you. I didnt realize that, like coke, methylphenidate was a DRI. Thats probably why ots been compared to the feeling of, as you said, "cheap coke."

I found my pupil size to decrease while on amphetamine - weird. During the come-down they got big, though. Not to hijack but anyone know why this was?

And this was actually my other question, ive noticed the same thing about how its when im coming down that my pupils tend to dilate, but while feeling the effects they tend to constrict. But I havent done it in a while so I thought maybe I may have remembered incorrectly

 

[selfassuredfreq+]

I just wanted to post here because I remember Focalin being my favorite drug as a teen ager believe it or not, I have a lot of experiance with this compound but my memory is kind of foggy on it honestly.
NOTE: FOCALIN IS NOT THE SAME AS RITALIN/CONCERTA, THOSE TWO Active ingrediants are Methylphenidate, a piperazine very very closely related to Focalin

Focalin= Dextromethylphenidate (Both are piperazines btw, little fun fact)
But anywho, from what I remember Dextromethylphenidate(Focalin) Was a lot cleaner then Methylphenidate, a lot more able to focus, and better euphoria. It's supperier in the ADHD pill catalogue to all except Adderal in my book maybe.

NOW, focalin vs. Vyvanse? Dexedrine is really long lasting depending and takes a lot more to dose, probably more speedy then euphoric
Where Focalin is rather a moderate time period, dexedrine can keep you up for ages EXPECIALLY if you compulsively redose for stims.

I found focalin way better, but I can't speak with much authority because I can't recall ever PERSONALLY eating a vyvanse, but a good friend of mine would eat em up like a rip in the space time continuem eats percievable matter. Ok, maybe thats a big exageration, but you get the picture.

If you have a choice between adderal or focalin, I'd say adderal, but against ANYTHING else, go with DMP(dextromethylphenidate) for recreation, while dexedrine might be good for a starter for a long work and school day.
Dexedrine can last long, so be carefull to not mix to many stimulants together or eat any MAOI!

 

[LOGan1314]

I found my pupil size to decrease while on amphetamine - weird. During the come-down they got big, though. Not to hijack but anyone know why this was?

EXACT same shit happens to me, even with large doses. Very interesting.

 

[jhnstnwll]

focalins a lot stronger

 

[Znegative]

THey're very different IMO.

Vyvanse, like adderall, is an amphetamine. In fact, its a prodrug to dextroamphetamine, which is what Adderall is mostly made up of. Basically, Vyvanse is like Dexadrine, just 1/2 as potent.

Focalin, is a DRI (dopamine Reuptake inhibitor), like cocaine. Focalin is only the dextro-isomer of methylphenidate (its generic name is Dextromethylphenidate). It's basically a stronger version of Ritalin, and supposedly smoother though IMO both dextromethylphenidate and regular old methylphenidate suck ass, are as addictive as hell while not being euphoric enough to warrant such fiendishness. I think the problem I had with it was that it feels enough like coke that it makes you want to redose again to feel the rush, but unlike cocaine, both ritalin and focalin are long lasting as hell, even when injected intravenously...it all amounts to one massive crash that is virtually intolerable.

I had the opportunity to get focalin the other day, and was even tempted to due to my fiendish nature towards drugs like it, but chose the amphetamines in the end. For some reason I always end up with a needle in my arm with DRI's and NDRI's-and thats not to say that focalin or ritalin feels like coke when injected, thats a huge myth- but you'll still end up chasing it like it does :/.

Anyway, I know you weren't asking my opinion but were asking about potency. Focalin is probably the stronger of the two, though it really depends how you take it (as oral dexmethylphenidate is absorbed at a really low percentage 11-30% I believe). However, it's still active at really low dosages ( i believe the Immediate release formula even is prescribed at 2.5mg), so even orally it can get you pretty spun.

Vyvanse, or Lisdexamphetamine, is weaker, but is not a DRI, but a DRA ('Dopamine Releasing Agent'). Like I said earlier, Lisdexamphetamine is metabolized into dextroamphetamine, and is about 1/2 as strong (I think 25mg Vyvanse is equivalent to 10mg Dextroamphetamine).

I'm assuming that these are not being prescribed to you right? Whatever you do, take them at different times. It could be really dangerous to use the two in combination, or especially if you use the Focalin after the Vyvanse.

 

[Ksa]

Focalin vs. Vyvanse is like Tylenol Vs. Codeine

Both codeine and Tylenol are processed in the liver so you can't get high off them, and the former are just bad highs.

 

[Znegative]

Focalin vs. Vyvanse is like Tylenol Vs. Codeine

Both codeine and Tylenol are processed in the liver so you can't get high off them, and the former are just bad highs.

What? I don't get that at all? First of all, the comparison doesn't make sense as Codeine is a CNS depressant not just an analgesic (like tylenol), and furthermore, if you don't have a tolerance to opiates, you certainly can get high off codeine.

I suppose comparing codeine to lisdexamphetamine/Vyvanse makes a bit of sense as they are both pro drugs. Also, claiming that Vyvanse or Focalin is a bad high is completely subjective. I know some people that way prefer Vyvanse to the other available prescription amphetamines, and if you search the internet, tons of people seem to dig dexmethylphenidate as well (though I personally think it is a shit high).

 

[AlphaMethylPhenyl]

THey're very different IMO.

Vyvanse, like adderall, is an amphetamine. In fact, its a prodrug to dextroamphetamine, which is what Adderall is mostly made up of. Basically, Vyvanse is like Dexadrine, just 1/2 as potent.

Focalin, is a DRI (dopamine Reuptake inhibitor), like cocaine. Focalin is only the dextro-isomer of methylphenidate (its generic name is Dextromethylphenidate). It's basically a stronger version of Ritalin, and supposedly smoother though IMO both dextromethylphenidate and regular old methylphenidate suck ass, are as addictive as hell while not being euphoric enough to warrant such fiendishness. I think the problem I had with it was that it feels enough like coke that it makes you want to redose again to feel the rush, but unlike cocaine, both ritalin and focalin are long lasting as hell, even when injected intravenously...it all amounts to one massive crash that is virtually intolerable.

I had the opportunity to get focalin the other day, and was even tempted to due to my fiendish nature towards drugs like it, but chose the amphetamines in the end. For some reason I always end up with a needle in my arm with DRI's and NDRI's-and thats not to say that focalin or ritalin feels like coke when injected, thats a huge myth- but you'll still end up chasing it like it does :/.

Anyway, I know you weren't asking my opinion but were asking about potency. Focalin is probably the stronger of the two, though it really depends how you take it (as oral dexmethylphenidate is absorbed at a really low percentage 11-30% I believe). However, it's still active at really low dosages ( i believe the Immediate release formula even is prescribed at 2.5mg), so even orally it can get you pretty spun.

Vyvanse, or Lisdexamphetamine, is weaker, but is not a DRI, but a DRA ('Dopamine Releasing Agent'). Like I said earlier, Lisdexamphetamine is metabolized into dextroamphetamine, and is about 1/2 as strong (I think 25mg Vyvanse is equivalent to 10mg Dextroamphetamine).

I'm assuming that these are not being prescribed to you right? Whatever you do, take them at different times. It could be really dangerous to use the two in combination, or especially if you use the Focalin after the Vyvanse.

You might want to ask about bupropion.

And I've tried methylphendate and only gotten a a short high followed by extreme fatigue and irritability, while vyvanse seems frankly empathogenic to me and is gentle.

 

[Ksa]

What? I don't get that at all? First of all, the comparison doesn't make sense as Codeine is a CNS depressant not just an analgesic (like tylenol), and furthermore, if you don't have a tolerance to opiates, you certainly can get high off codeine.

I suppose comparing codeine to lisdexamphetamine/Vyvanse makes a bit of sense as they are both pro drugs. Also, claiming that Vyvanse or Focalin is a bad high is completely subjective. I know some people that way prefer Vyvanse to the other available prescription amphetamines, and if you search the internet, tons of people seem to dig dexmethylphenidate as well (though I personally think it is a shit high).

It's impossible for such a simple statement not to be innacurate, Just tried to put it in a shell.

 

[MountEdenDubstep]

Im planning to try 50 mg vyvanse, which seems like a good starting dose.

Try 40mg for starters. Do 50 if you feel like you need more after a few weeks.

 

[wireed1234]

in my experience focalin works better every time all the time. Vyvanse(dislexamphetamine)- cannot be used besides orally and its high last for a maximum of 1 hour. The rest of the effects you receive from vyvanse is a slight depression and a major need to find a pick me up whether it be a drink or a drug. Focalin on the other hands works for hours on end and no i don't understand how they isolated focalin from ritalin but whatever those scientists did, made a drug with a much more effective drug for the treatment of add and adhd patients

 

[sheramy brewer]

in my experience focalin works better every time all the time. Vyvanse(dislexamphetamine)- cannot be used besides orally and its high last for a maximum of 1 hour. The rest of the effects you receive from vyvanse is a slight depression and a major need to find a pick me up whether it be a drink or a drug. Focalin on the other hands works for hours on end and no i don't understand how they isolated focalin from ritalin but whatever those scientists did, made a drug with a much more effective drug for the treatment of add and adhd patients

you made me feel so much better,my 13 year old son has been on vvyance 70 and today switches to focalin 20!I was worried about the dramatic change, but I feel better seeing how it has made a great impact on you

 

[KINGCRIMSON]

vyvance or Lisdexamfetamine sucks. notice the f instead of the ph. The mol structure of vyvance is cleaved by stomach enzymes ONLY. Then and only then does it become active. and it is extremely slow release at least it was for me. No matter how much they increased vyvance dose it never worked and was never even close to Ritalin Sr. Vyvance is basically the re-release of adderall. Which is dextroamphetamine or just dexamphetimine, vyvance is dexamphetimine with the lis added which is apparently the molecule that has to be cleaved by the stomach enzymes. If this isnt cleaved by the enzymes than its completely inert. So there is no other route of admin except oral and the ph changed to f and that allowed the company that makes both vyvance and adderall to re-release adderall under a new name and formulation which enabled them re-copyright the drug and make an additional trillion dollers from an already existing drug. In other words its a big scam.