Benzos Etizolam Mega Thread v1

[belfort]

phatass-3-4 mg of etizolam is not a small recreational dose..that would have most people falling asleep...i just started taking etizolam and 2 mgs sends me into a nice calm place but i am fighting back sleep about 2 hours later...

lastest-how long were you taking etizolam every day before u noticed tolerance problems??i dont plan on taking it anymore than twice a week..

to the OP, etizolam isnt a drug i take to get high, its simply something to take if you want a chilled out evening sitting outside or watching movies..

 

[lastest]

lastest-how long were you taking etizolam every day before u noticed tolerance problems??i dont plan on taking it anymore than twice a week..

About seven weeks until the subjective effects became completely absent at 2mg. I tapered off and stopped completely but that only lasted a week. When I went back to it tolerance had only decreased a little (as you might expect) but I carried on with it anyway, like an idiot. I'm tapering again now and plan to be off completely fairly soon, and then I'm going to try and never touch a benzo/thienodiazapine for as long as I live. Wish me luck...

 

[BruceLeeSwag]

phatass-3-4 mg of etizolam is not a small recreational dose..that would have most people falling asleep...i just started taking etizolam and 2 mgs sends me into a nice calm place but i am fighting back sleep about 2 hours later...

lastest-how long were you taking etizolam every day before u noticed tolerance problems??i dont plan on taking it anymore than twice a week..

to the OP, etizolam isnt a drug i take to get high, its simply something to take if you want a chilled out evening sitting outside or watching movies..

I found allways with benzos it goes like this

low dose=relaxation
higher dose=sleepyness
higher dose=drowsiness/more sleepy
higher dose=drunkenness & you start to do stupid things, but you become more alert
higher dose=blackout

Medium doses make you sleepy, but once you keep going you get a surprising amount of energy, like when you get drunk, after 5 drinks you feel a bit drowsy and tired, after 10 you feel some sort of energy.

 

[PainInTheAss]

I belive the pink/reddish ones from "that two almost similar named vendors" contain 1mg. hadn't touched shit expect or hasj or 2 weeks because o holiday, 2 reddies+a few beers and tons of dank only left me walking slightly out of balance, besides eeling awesome relaxed and anxiety was not even in my grammarbook that evening. Curious to lab test though, but the lady would not take it from me, because of high noon season of MDMA. gonna return next week and saying, I bought this as a 75mg X pill.

Overall awesome drug. Perect for harsh stim comedowns/sleeplessness after psych's, half a reddie(0,5mg total I belive) is enough to let me smoke fat blunts all night without a hint of anxiety. Wanna have a relaxing night? 1mg+ 2-3 beers till you feel you're done.

 

[belfort]

strangely last night i took 1 mg and it almost had me wired, easily agitated..i was very surprised by this feeling..my sleep was jerky, i woke up this morning in a shitty mood, still am for the most part..is it common for random benzo use to leave one with low mood the next day??i dont take them every day so..

 

[belfort]

is it common for benzos or etizolam to cause a next day hangover of sorts?i use etizolam 1-2 a week and last night i took some and this morning i woke up in shitty mood, low energy..then again, my sleep was crappy so im not sure..

 

[belfort]

lastest-now do you mean after 7 weeks u lost all the recreational effects AND the anti-anxiety effects??i assume you mean u lost the 'high' from it..surely it still works for your anxiety right??i wish u luck in kicking, give neurontin a try, it works wonders for benzo/opiate withdrawals..

 

[-Guido-]

is it common for benzos or etizolam to cause a next day hangover of sorts?i use etizolam 1-2 a week and last night i took some and this morning i woke up in shitty mood, low energy..then again, my sleep was crappy so im not sure..

Yup. Just because you sleep on benzos, doesn't mean you are getting quality sleep.

 

[lastest]

^ Yes, that's basically what I mean. When I say 'subjective effects' I was talking about the muscle relaxation and 'drunken' disinhibition - in other words the 'high' as you say. In terms of anxiety, it's not something that I suffer from to an abnormal level every day anyway, although my discovery of etizolam came quite soon after a pretty shitty event in my life and I've begun to think maybe I've been self medicating for anxiety without realising it. But it's hard to quantify how much effect it has in that regard, or how tolerant I've become because I think my anxiety is naturally below clinically diagnosable levels anyway.

Thanks for your advice, and for wishing me luck.

 

[belfort]

^^damn i wonder how everyday benzo users deal with this??i would hate waking up feeling like that every day..

 

[iResearch]

Etizolam are sold in 1mg blue and 2mg red home made pellets and 1mg blue branded with white inside if you snap them

 

[Mercc96]

try having fibromyalgia , i wake up feeling like shit even if i get a supposed ' good nights sleep'

 

[DubNaut]

You can all help me answer this question:

Is etizolam metabolized by CYP3A4, so would an inhibitor such as cimetidine would increase blood plasma concentration and duration/intensity?

Thanks for the all the information everyone has provided!

bumping this question for answer/links

keep putting off testing it, i'd much rather use beer !
didn't notice with klonopin although i doubt i would anyway

 

[mydrugbuddy]

bumping this question for answer/links

keep putting off testing it, i'd much rather use beer !
didn't notice with klonopin although i doubt i would anyway

Just found this, which you could have easily found yourself by typing in "etizolam metabolized by" into the Yahoo search engine: Google or what ever one you use is your friend ! This was the 6th result that came up, and is a proper scientific study on precisely what you are wanting to know.

Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism.
Araki K, Yasui-Furukori N, Fukasawa T, Aoshima T, Suzuki A, Inoue Y, Tateishi T, Otani K.
Source

Department of Neuropsychiatry, Yamagata University School of Medicine, 990-9585 Yamagata, Japan.
Abstract
OBJECTIVE:

To clarify the involvement of cytochrome P450 (CYP) 3A4 in the metabolism of etizolam.
METHODS:

The effects of itraconazole, a potent and specific inhibitor of CYP3A4, on the single oral dose pharmacokinetics and pharmacodynamics of etizolam were examined. Twelve healthy male volunteers received itraconazole (200 mg/day) or placebo for 7 days in a double-blind randomized crossover manner, and on the 6th day they received a single oral 1-mg dose of etizolam. Blood samplings and evaluation of psychomotor function using the Digit Symbol Substitution Test and Stanford Sleepiness Scale were conducted up to 24 h after etizolam dosing. Plasma concentration of etizolam was measured by means of high-performance liquid chromatography.
RESULTS:

Itraconazole treatment significantly increased the total area under the plasma concentration-time curve (AUC; 213+/-106 ng rectangle h/ml versus 326+/-166 ng rectangle h/ml, P<0.001) and the elimination half-life (12.0+/-5.4 h versus 17.3+/-7.4 h, P<0.01) of etizolam. The 90% confidence interval of the itraconazole/placebo ratio of the total AUC was 1.38-1.68, indicating a significant effect of itraconazole. No significant change was induced by itraconazole in the two pharmacodynamic parameters.
CONCLUSION:

The present study suggests that itraconazole inhibits the metabolism of etizolam, providing evidence that CYP3A4 is at least partly involved in etizolam metabolism.

http://www.ncbi.nlm.nih.gov/pubmed/15232663

I tried cimetidine myself for the first time last night. It did seem to noticeably potentiate both poppy pod tea and etizolam. I am meant to tapering off my PPT tea so i shouldn't really be using potentiators atm, as they are just gonna mess up the taper. Should really save them for when i get clear of daily use of Opis, and can then possibly consider just taking them occasionally. I might have to face the fact that I may not be strong or disciplined enough to take Opis on an occasional basis. Anyway, going off topic now, sorry.

 

[Xamkou]

Funny how after taking one 2mg pellet, you suddenly find two days have passed, 8x 2mg pellets are "missing" and you have no recollection of the previous 48 hours. Fucking nice one

 

[Xamkou]

In the long term they are bad for making anxiety worse if you take them continuously for any length of time.. Sorry to be so gloomy, i thought they were a total wonder drug at first, i guess they are, but only if you can carefully control how often you take them. That was/is a lot harder than i ever expected.

I get ya, I really do

 

[Mercc96]

I have a funny memory associated with etizolam - sometime last year I went to check out a uni in liverpool. Decided it would be a good idea to start snorting a few of those old blue ones with the crappy binder. I think i snorted quite a few and popped some oxy, wandered about the uni talking to the english teachers full to the brim with confidence. Nothing seemed unusual except for my blue stained nose, pinned pupils and excessive talking. Tried fentanyl that weekend also.

 

[belfort]

luckily i have yet to get any of the 'black out' problems on etizolam..i only take 2 mgs though so..

Xamkou-u have had same problem with etizolam?

 

[kace]

Oh damn, I love these things far too much, I don't know what to do. :/

Like others have said, these things are a godsend for anxiety and insomnia. I fell in love with these things from the start as for the first time in my life I go about my days being happy and sociable! I can talk to others and feel at ease, and all in all feel content and relaxed when taking them daily instead of the anxious depressed shy awkward non taking me. It's just so nice being able to smile, socialise and sleep.

However I've stupidly spent all my money and am now completely broke and pill less.. not good. The withdrawals are getting worse each time I go from all to nothing. How bad is it is it to go from 4-8mgs a day to none on a long term basis?


I feel like I can the feel the toll it's taking on my body, and mentally feel stupider with a really bad memory. Also I get really bad blackouts, has got me into a very bad position... Sometimes the black outs last whole weekends. Mix these with alcohol and expect to go from feeling fine at 7pm to waking up the next day with no recollection of the nights previous events. My memory is bad even in the days when I don't mix them with alcohol.. I have noticed my speech has gotten worse, people have trouble understanding me and I find it hard to form sentences and spell. I'm reading and studying in attempt to try and counteract these problems, but is there any point? I can't help but feel I now have the mental abilities of a senile person.

If I continue to take these daily how badly will it mess with my body and mind? Although I'm worried, I don't think I can give them up.

I'm getting worsening stomach cramps, insomnia, paranois, nauseousness with eye twitches and bruises. Anything to lessen these symptoms? The anxiety is just horrible, the impending doom stomach sensation, racing heart and paranoia are back. I just want to order another bulk so badly but I don't get paid for a while. What do I do? Should I see a doctor? I bet they would have no idea about the drug.

TLDR: How bad are the long term effects? What have you noticed?

 

[belfort]

^^withdrawals will just get worse...memory loss will just get worse as well unfortunately..obviously benzos help you very much though in certain areas..u and many others on here share the same social handicaps...therapy and other medication may help..how can u go broke buying etizolam though, the stuff is cheap...