Efficacy of Lyrica in the treatment of acute opiate w/d

Ixchellian

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Ok, I've been waiting to tell people about this, because I don't want someone to try it outside of their doctor's supervision and then have them drop dead or explode in a cinematic ball of death. Ok not literally xD
But that's my first disclaimer here.

I apologize that this is a long post first.....

Morphine IR (slammed mostly) was my DOC, then I went to pods for almost a year, and the w/d's from those were every bit as bad as morphine.... along with a few other nasty surprises that I think were w/d's from the other opiate alkaloids in poppy pods.

I started taking pregabalin at 75mg x twice daily, and have been titrated up to the 150mg x 2 daily.
I've just been waiting so I could be sure. I don't like giving people bad advice, especially when it comes to drugs & kicking junk.
~~~~~~~~

- It almost completely zapped the leg-&-back spasms, and I had a supply of muscle-relaxers to deal with the rest.

- The cold burn was significantly reduced, would come only in occasional flashes, and my skin didn't hurt to the touch either.
I was still uncomfortable temperature-wise, but not so much that I wanted to sit in hot water with a bag of ice on my head.

- The rhinitus-related symptoms were still present, and tearing up of the eyes as well (this was more an emotional symptom methinks).
Antihistamines helped in this respect.

- Gut function came back fast, but not with a vengance along with vomiting I normally get.
My stomach felt uneasy from all the gurglings, and I didn't feel like eating as normal. Two anti-nausea meds helped here; Omeprazole before eating & Phenergan for random bouts. Phenergan also knocks my ass out cold, so it helped at night.

- Energy wise, I didn't feel like I could go walk around the block, but I could drag myself up and walk around the house at least.

- Emotionally, I'm well & truly fucked in that AO normally, and normal w/d's turns it into crippling depression. Lyrica & buproprion leveled that out quite well.
The ONLY times I've ever thought about creating an abstract high-velocity splatter-painting on a wall with my grey-matter has been during w/d's. And at my doc's perscribed dosage of 300mg x 2 daily I still felt more level-headed, had fewer random crying-jags, and had more interest in doing stuff like playing a computer-game.

DISCLAMER- I don't suggest that anybody take as much as I have. Pfizer's max recommended dosage & perscribing-instructions for pregabalin is 600mg/daily. And it is a potentiator of benzos, so be aware when if mixing the two
This is Pfizer's Lyrica page.
This is interesting for we junkys, and is directly from Pfizer's detailed medication study -
"Pharmacodynamics
Multiple oral doses of LYRICA were co-administered with oxycodone, lorazepam, or ethanol.
Although no pharmacokinetic interactions were seen, additive effects on cognitive and gross
motor functioning were seen when LYRICA was co-administered with these drugs. No clinically
important effects on respiration were seen."

That being said, Lyrica makes me hyper, talkative, and happy(er) at high individual doses (I'm talking like 1200mg), and did this even in acute w/d. It feels sorta like the come-up on exstacy. HOWEVER...... it does make me very dizzy, made it hard to focus on things, discoordinated, and worsens my insomnia.
Note: At normal doses, it doesn't give me any negative side-effects.... unless the happy ones count too.

I didn't develop quite the healthy addiction to morphine because I was doing it for for fun, it's cause I got fucked up in Iraq. And as much as I hated being a junky and wanted to stop, just the thought of the pain returning (this time with some serious emotional/existential pain) would dissuade me. I've taken a lot of things to get rid of my back & leg pain, up to and including some pretty hefty drug combinations that would've killed a normal man... several, probably.

And Lyrica amazingly has done what those couldn't. It might work for me and not for the next fellow junky trying to kick, but it's worth at least a goddamned go of it, if one is really intent on kicking dope.

But even better is the benefits for chronic-pain and fibro sufferers. I accidently figured out about it's helping ease w/d's. So yeah, I've been the guinea pig on this one. At least my back & legs don't hurt (as much) anymore.
 
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