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Ecstacy causes memory loss - newspaper article - comments please.....

frisky

Bluelighter
Joined
Jan 6, 2000
Messages
14
Location
Sydney, NSW, Australia
Hi, I found this online at the Sydney Morning Herald's Website. (I've posted the article here as they usually delete it off the site after a week or 2 - The link is at the bottom of this article so you can go to it while it is still current.)
Makes interesting reading, especially the risk factors of dying from a pill. Safer than riding a horse....I guess we all knew that. They also mention that the suspicion of memory loss only applies to high dosage / very frequent use and those that dont use often or in low dose, there is nothing solid yet to suggest any adverse affects.
In light of this research, perhaps the government should start putting some more money into this type of research instead of wasting it on the "drug war". If one day the researchers do conclude that this drug is *relatively* safe (nothing in this day and age comes risk free), perhaps the government might move to legalise it. I guess the upside of this is
i) that it is not any more dangerous that getting yourself blind drunk on alcohol(getting agro, going into a coma, losing brain cells)
ii) that legalisation will produce cleaner / safer pills produced by professional government endorsed entities.
iii) police resources and public money better spent else where on REAL crimes.
Your opinions peoples....
:-)
Regards,
Frisky.
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Rhapsody so blue, the downside of ecstasy.
Research suggests designer drug may cause brain damage, write Wayne Hall, Iain McGregor and Brendon Boot.
THE past week has been an important time for both those who study the effects of the drug ecstasy and for those who take it.
A British study reported that long-term ecstasy users have poor memories. A German research group has suggested that even infrequent use of ecstasy may be enough to decrease your memory and reasoning ability. On Saturday, the respected medical journal The Lancet published a review of the scientific evidence about this drug. In it, we - a group of Sydney researchers - argue that ecstasy use is a much more hazardous activity than many users realise.
The real hazards of ecstasy use have little to do with the rare fatalities which we read about in newspaper headlines. Ecstasy users have largely discounted these sensationalist warnings about "death on the dance floor".
They have good reason: in terms of the risk of death, taking an ecstasy tablet is safer than riding a horse. Indeed, among users, ecstasy has a reputation as a safe drug because it does not produce the craving caused by heroin and cocaine.
The real hazard of ecstasy use is that it is neurotoxic, which means it can damage nerve cells in the brain that contain the chemical serotonin. Evidence that ecstasy can be neurotoxic has emerged over the past decade. While there are methodological difficulties in such research, the consistency of findings raises a strong suspicion that ecstasy is damaging the brains of some users.
It is essential to point out that these results may only apply to long-term, high-dose users of the drug. Whether occasional use of low doses of ecstasy causes damage is not yet known.
We are concerned that more and more ecstasy users are using the drug in a way that increases the risk of these neurotoxic effects. The risk factors include: using two or more tablets of ecstasy at a time, using fortnightly or more often, using ecstasy for 24 hours or more at a time, overheating the body (for example, by dancing for hours at a time) and snorting or injecting ecstasy.
Almost all respondents to a survey of 329 Australian users identified one or more of these risk factors in their use, yet 94 per cent believed that their pattern of use was safe.
If ecstasy does damage serotonin nerve cells in humans, what effects should we expect? Firstly, it is important to note that neurotoxic damage can occur in the absence of symptoms: ecstasy users may damage their nerve cells without realising it. Nevertheless, symptoms are evident in some users. Research shows that a poorly functioning serotonin system is most often linked to depression and memory problems. So it is not surprising that some ecstasy users report irritability and depression that are related to how often and how much ecstasy they use. Nor is it surprising that there are now seven studies reporting memory problems in users.
Ethical reasons prevent researchers from doing definitive studies to test the effects of ecstasy on human brain function. But we should not let this blind us to the wide array of evidence which raises a strong suspicion that ecstasy can produce neurotoxic effects in some recreational users.
If we had the same type of evidence of harm from a pesticide or a pharmaceutical drug it would be withdrawn from the market.
Current and potential users of ecstasy need to be informed of these risks by peers in the dance party milieu and through the media they use, such as videos and the Internet. Sensationalism and paternalistic finger-waving by researchers and the media only serve to alienate those to whom we wish to provide information.
Thus, non-alarmist and accurate information is required that acknowledges uncertainties about the risks of occasional use of low doses of ecstasy, while emphasising the clearer risks that heavier and more frequent ecstasy users probably face.
Professor Wayne Hall is executive director of the National Drug and Alcohol Research Centre. Dr Iain McGregor is a senior lecturer in psychology at the University of Sydney. Brendon Boot is a PhD student at the University of Sydney.
http://www.smh.com.au/news/0005/23/features/features03.html
 
hiya
i just realised i made a post about this very topic....oops, i'll delete that post
anyway here is what i wrote
posted 22 May 2000 08:23 PM
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During a mid morning procrastination session i came across this article. http://www.smh.com.au/news/0005/23/features/features03.html
it doesn't really say anything new, altough they didn't take the e "killer drug taking our babies away" line. the article warned against unknown long term effects, and tried to identify some risk factors.
this article didn't take the war on drugs view of ecstacy, altough the researchers interviewed have quite a cautious view on the risks of e. they're scientists, and we scientists by tradition very timid in what conclusions we'll make from our data.
does anyone have the ref. for the review of e literature that they mention in that article.
apparently it's from a recent copy of the lancet.
 
i particularly like the last line of the artice
"Thus, non-alarmist and accurate information is required that acknowledges uncertainties about the risks of occasional use of low doses of ecstasy, while emphasising the clearer risks that heavier and more frequent ecstasy users probably face."
viva la bluelight
j
 
Hi, thought i would add my 2c worth...
The article was called "MDMA (Ecstasy) neurotoxicity: assessing and
communicating the risks" from volume 355 issue 9217 of the Lancet
(http://www.thelancet.com). You have to subscribe to the Lancet to get this
full article. Hey med students (or librarians) out there - can you help?
that's the best i can do.....
FYI - Archive of old Lancet issues can be found at http://www.hbz-nrw.de/elsevier/01406736/. This volume is not there
yet...maybe in a couple of months. Maybe it will be on drugtexts soon??
 
Hi, thought i would add my 2c worth...
The article was called "MDMA (Ecstasy) neurotoxicity: assessing and
communicating the risks" from volume 355 issue 9217 of the Lancet
(http://www.thelancet.com). You have to subscribe to the Lancet to get this
full article. Hey med students (or librarians) out there - can you help?
that's the best i can do.....
FYI - Archive of old Lancet issues can be found at http://www.hbz-nrw.de/elsevier/01406736/. This volume is not there
yet...maybe in a couple of months. Maybe it will be on drugtexts soon??
 
I firmly believe that all drugs fuck u up. permanent or not. XTC in my mind in no different. but i think of it this way: a few memory cells and some depression (which is not incurable) for hours and hours of other wordly pleazure...
wink.gif
 
I read some info on a UK study that compared memory capacity and depression between alco drinkers and e muchers in the UK. Naturally both caused a significant effect but E caused a greater effect than alcohol. I am sure it was assessing when things came 'back to normal'.....so yeah...this might be vague...but er moderation for anything
smile.gif
 
my mum is doing a masters, i think she gets a subscription. hmmmm
smile.gif

if you were willing to make a trip to your local university medical library then you would definitely find a copy there. it's a pretty common journal if my mum gets it. try searching medline
http://gateway.ovid.com/ovidweb.cgi?T=JS&MODE=ovid&PAGE=main&D=mesz
login: uos999
password: almond5
if that url doesn't work try http://www.library.usyd.edu.au
and follow the database link
[This message has been edited by j_swift (edited 23 May 2000).]
 
There was a short item about this topic on A Current Affair last night, basically just a TV version of the article for those who don't read the papers I guess, because their interviewee/interviewer basically quoted this article. "Heavy users"... "more than one pill per night"... "more than 24 hours in a row"... "brain patterns similar to alzheimers patients in the heaviest users"... etc.
BigTrancer
smile.gif
 
Ummmm can someone tell me again how I
post a reply here....
I totally forgot
Oh no, who am I?
What am I?
Omigosh, hope I might find my way to Utopia
Memory loss is sad.... I'm fretting now,
what if I forget the way to Homebush!
HELP she YELPS!!!
[This message has been edited by RaY_Of_THa_DaWn (edited 25 May 2000).]
 
www.mapinc.org/drugnews/v00/n671/a09.html
I find it odd that:
1) they were given "general knowledge tests" to prove that "one group was not naturally more intelligent than the other". Since when has general knowledge been a good indicator of intelligence. Surely that is a memory skill, not one of cognitive ability? If they were scoring the same on general knowledge, how did their memory skills suddenly drop when given different memory tasks?
2)28 people who didn't smoke but took ecstasy couldn't be found. I know at least four including myself.
3)the marijuana-only group performed just as well as the no-drug group. My Home Secretary, Mr Jack Straw, repeatedly tells me that marijuana cannot be legalised because it has been PROVEN to affect short term memory skills (and leads to heroin addiction because most heroin addicts also smoke weed - QED).
4)no-one seems to care that we have no idea how well the ecstasy users would have performed in the same tasks before taking E. It's all very well saying that they performed worse than other people but how can we know that wouldn't have happened anyway? The sample size is nowhere near large enough to make sweeping generalisations.
5)All ecstasy users scored within the normal range in the tests ie THEIR RESULTS WERE NORMAL. Why are we assuming there is something wrong with people scoring NORMAL results?
6)lifestyle hasn't been taken into account. I'm guessing that E users spend more time in clubs and having late nights than non-drug users and possibly spend less time sat in the house reading a good book than no-drug users. Comparing their education levels when they are in their mid-twenties and presumably several years away from school surely isn't a good measure of the state of their learning in the present day? Again, I'm going to go out on a limb here and suggest that E users may have slightly different personalities that people who wouldn't dream of touching the stuff. In my experience the club-going party person tends to be less career and work orientated as they are a little too busy enjoying their youth. Someone who doesn't go out much and concentrates more on career or work by preference presumably is going to have better concentration skills than someone who likes to get wrecked at the weekends and recover through the week. Let's not forget memory and concentration are both skills that can be learned.
Right, Ive had enough of picking that one to shreds, I'm off to see if I can find a copy of the British study so I can dicredit that too.
I should point out that there might well be something in this but I really can't see how such a definite conclusion was reached with so many uncontrlled variables flapping about.
[This message has been edited by paddyboy (edited 29 May 2000).]
 
well done paddyboy... successfully pointed out all of the methodological problems in that study that any first year psych student could... where do these people get off not doing their background research, preliminary studies and using common sense??
i'm doing psych at uni (3rd year) and hopefully (if i get my act together and don't come down with a sudden case of alzheimers-sp?) will be doing some sort of postgrad work to do with party drug use... hopefully my study will give more reliable outcomes
but seriously, i do worry about the state of my brain sometimes... too much mashing has made it way more fragile than it used to be, and i have found that i tend to get more down than i used to... memory can sometimes be a bitch but maybe i'm just getting old, running low on space up there?!
 
Guys,
I am dissapointed that we continue to ignore a body of research that suggests heavy and long term use of ecstasy is going to have repercussions for us.
"Every action has an equal and opposite reaction".
I guess i'm more for preaching moderation and harm minimisation here than worrying about the validity of current research.
pinger
 
pinger, it's not that we don't worry about that... it's just that studies like this are hard to take seriously when they are full of flaws.
of course everyone worries about what they do to their brain. i do too, and perhaps if the researchers could develop a study that is a bit more valid, the true dangers of drug use may be realised for a few more people.
 
I agree that more defintive tests need to be carried so we can comprehensively be sure of what the long term effects of MDMA usage truly are but it's now platanly obvious that heavy usage is going to effect your memory and anyone who denies this is really going to do there brain harm !!!!! So I think moderation and MDMA should now go hand in hand
Cheers
Chill
 
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