dysphoria from alcohol opiates and pot

[psychedelic food]

Whenever i drink alcohol, take opiates or smoke pot i get very dysphoric. Alcohol gives me a better ability to talk and releases inhibitions. If i drink enough i get the spins. Opiates just make me generally dysphoric. Pot either makes me very dysphoric or gives me a major panic attack with vivid hallucinations. I have used all of these in the past and they have made me very euphoric. But the past couple years they have just made me dysphoric. I also have felt generally emotionally numb the past couple years. What do you think it is that causes it and more importantly want can i do to fix it?

 

[surly1]

THC is strangely dysphoric considering it's popularity.

 

[negrogesic]

THC can certainly be quite dysphoric....

Both alcohol and opiates can have elements of dysphoria (particularly the former). Perhaps you are depressed; opiates and alcohol can exacerbate depression...

 

[shibireru]

Hey, I'm pretty much in exactly the same situation. It's nice to know that there are others like me.

I am almost completely emotionally numb (as I have said again and again here on this forum in my moments desperation, as its thoroughly annoyed denizens will attest). I have almost no ambitions, no motivation, no libido, etc... I sleep twelve hours or so, and then waste the rest of the day spacing out in front of the computer, possibly devoting as much as five minutes of my waking time to study of various subjects in which I used to have great interest. On the other hand, at least now I don't feel so gut-wrenchingly, I-have-to-stab-myself-in-the-chest-right-now! suicidal as I used to. I also have a certain degree of mental clarity which I hadn't had when I was younger and much more emotional.

Anyways, when I drink alcohol or smoke marijuana, I always become severely dysphoric. I've never enjoyed either of them. In the case of marijuana, I have panic attacks far more severe than any marijuana-induced panic attack which any of my nominal friends has seen, each of whom has a long and storied history of marijuana use and abuse. And, as sorry as I am to say so, I recently discovered that opioids now produce dysphoria in me, too, which aggrieves me a great deal since opioids had been my favorite of all classes of substances. I recently tried Fentanyl and it was just total shit; at first I ascribed this fact to insufficient activity at the delta-opioid receptor, but now I am realizing that it's probably only because there's something seriously wrong with my brain.

I am afraid I can't answer your question. I have tried dozens and dozens of medications and nothing has helped. If I find something that works, I'll pm you. Within a week or two I'll be trying Tianeptine again, this time with a far larger supply. Hopefully that will produce some long term changes in brain structure that will restore my ability to feel. (That hope isn't based on anything, of course - notwithstanding wishful thinking.)

Good luck.

 

[FrostyMcFailure]

THC is strangely dysphoric considering it's popularity.

well maybe its strangely popular because its dysphoric, ever think about that!?

 

[wreckhead]

Weed made me dysphoric when I was a benzo addict. Now I it. Took a lot of solitary smoking sessions to become comfortable with it though.

I am almost completely emotionally numb (as I have said again and again here on this forum in my moments desperation, as its thoroughly annoyed denizens will attest). I have almost no ambitions, no motivation, no libido, etc...

Your description actually fits me like a glove. Have you considered schizoid personality disorder? I'm not totally sure myself, but it does explain my complete lack of... anything.

 

[mindtools]

psychedelic food, maybe you're family roots are asian? I've heard that (because of lack of some enzymes) they can get dysphoric when using this substances

 

[Tsukasa]

Whenever i drink alcohol, take opiates or smoke pot i get very dysphoric. Alcohol gives me a better ability to talk and releases inhibitions. If i drink enough i get the spins. Opiates just make me generally dysphoric. Pot either makes me very dysphoric or gives me a major panic attack with vivid hallucinations. I have used all of these in the past and they have made me very euphoric. But the past couple years they have just made me dysphoric. I also have felt generally emotionally numb the past couple years. What do you think it is that causes it and more importantly want can i do to fix it?

what kind of opiates? kappa-agonists like pentazocine (talwin) are definately dysphoric, to me atleast.

Pot however, never made me dysphoric, but can be uncomfortable at higher doses. Though I think it might be because it exacerbates mental disorder which you have. it also turns your emotional numbness into the opposite (5-HT inhibition), and you're forced to think about your situation more which can make you depressed. Other contributing factors may include the adverse effects such as paranoia/anxious thoughts, anxiety, cottonmouth, diziness/confusion, tachycardia, coughing, etc. Indica dominant strains might be better for you, because they act more as anti-psychotics and are more sedating. Sativa's are the exact opposite - more trippy and stimulating.

 

[shibireru]

Your description actually fits me like a glove. Have you considered schizoid personality disorder? I'm not totally sure myself, but it does explain my complete lack of... anything.

Yes, I have considered it. I also fit to one extent or another the symptomatology of the following psychiatric disorders (I am not saying that I have them all): Melancholic clinical depression, dysthymia, simple schizophrenia (hardly distinguishable from dysthymia or severe depression. In fact, they seem not to be separate pscyhopathological entities at all in terms of aetiology, differing little if at all by presentation.), schizoid personality disorder, bipolar disorder type II, cyclothymia, body dysmorphic disorder, dependent personality disorder, avoidant personality disorder (at least when I am in the physical presence of others), panic disorder, post-traumatic stress disorder, social anxiety disorder, generalized anxiety disorder... and err.... hypochondriasis? (Listed in no particular order)

As to which disorders I think most likely to be associated with severe apathy or alexithymia? Melancholic clinical depression, PTSD, dysthymia, and simple schizophrenia. (Again, no particular order)

 

[wreckhead]

post

Strangely enough, since posting previously my mental disorders have one-by-one abated to the point of being negligible. I haven't put myself in any particularly stressful situations, but this is really promising.

It's all thanks to my daily regimen:

• Magnesium malate 4000mg (equals 600mg elemental magnesium)
• Taurine 3g
• Inositol 12g
• Multivitamin/mineral/B complex (includes stuff like zinc, folic acid, etc.)
• 1g EPA, 1g DHA (fish oils)
• 1g l-theanine
• 1g rhodiola rosea

 

[dorothyperkins]

^^ So since yesterday?!

well maybe its strangely popular because its dysphoric, ever think about that!?

lol

OP, maybe stop looking to drugs to make you happy and try and make yourself happy, generally. Perhaps then you'll be able to feel euphoric again when you take them, or maybe you won't even want to take them?

 

[leungkachong]

Shibireru: I would go the opposite route w.r.t. calling simple schizophrenia aetiologically (you did mean causatively? thats what it means) indistinguishable from dysthymia and major depressive disorder. First of all, dysthymia is defined to be a chronic-but-relatively mild (in intenisty) mood alteration, which is very different from major depressive disorder. (As another example) there is no 'relapse-worsening' effect in dysthymia. More importantly (when you talk about disease aetiology), the neuroarchictural and neurochemical differences between these diseases are plentiful (no schnizophrenia-like increased lateral ventricle size in the depressive disorders,.. no correlation with flu-like infection during early pregnancy.. completely different associated genetic traits and dug-treatment response... the list can go on). In fact, the more likely scenario is that schizophrenia, dysthymia, and MDD make up a VERY LARGE number of disorders that have been mistakenly classified only as these 3.

Also, the diagnosis of PTSD necessitates a psychologically traumatic event... thankfully that is not sufficient, but definitely necessary. If you suffer from symptoms which are similar to PTSD without a causative/triggering trauma, you do not fit the diagnostic criteria. Especially, if you feel that the 'trauma' inducing PTSD is something that would be commonplace (such as extreme psychological reactions to normal social interaction), treating this as PTSD would be much less effeective than approaching it as the appropriate anxiety disorder.

On an unrelated note....
With these points made, I must finish by ask that psychology die and move out of the way for real science... and join it's place in the land of philosophy of mind with a (bastardized) scientific process fetish.

 

[shibireru]

• Magnesium malate 4000mg (equals 600mg elemental magnesium)
• Taurine 3g
• Inositol 12g
• Multivitamin/mineral/B complex (includes stuff like zinc, folic acid, etc.)
• 1g EPA, 1g DHA (fish oils)
• 1g l-theanine
• 1g rhodiola rosea

With the exception of Taurine, I have tried all of those. They don't work for me very well at all.

I don't know how wise it is, by the way, to take that much magnesium, rhodiola, and l-theanine. The eicosapentaenoic aid, too, isn't particularly beneficial if not quite harmful. I believe I read that it may negate many of the beneficial effects of docosahexaenoic acid.

Additionally, I would expect that that supplement regimen would cause severe confusion and blunting of cognitive abilities. (temporary of course... probably)


Leungkachong-

What I meant was merely that simple schizophrenia, unlike paranoid, hebephrenic or catatonic schizophrenia, seems to be a superfluous clinical or diagnostic entity, since in most cases a person with a diagnosis of simple schizophrenia could just as readily obtain a diagnosis of dysthymia or melancholic major depression. There are cases of Schizophrenia, I believe, (or at least Schizophreniform pathologies) where a decrease in brain volume and an enlargement of the ventricles is not observed. Simple schizophrenia appears to be such a sort of Schizophrenia. In that sense, it is perhaps a condition indistinguishable from dysthymia or perhaps major depressive disorder aetiologically. Although, as you mention, either of the latter terms may very well subsume dozens of different aetiologies.

I have experienced plenty of extremely traumatic events.

I never said that all of those disorders I listed were neurostructurally or neurochemically distinct.

 

[wreckhead]

I don't know how wise it is, by the way, to take that much magnesium, rhodiola, and l-theanine.

600mg elemental Mg is perfectly safe, AFAIK. Theanine has been demonstrated entirely non-toxic in mega doses, at least in rats. Rhodiola too has a good safety profile.

You're right -- it probably isn't wise to take such excessive doses, but I wasn't in any sort of danger.

The eicosapentaenoic aid, too, isn't particularly beneficial if not quite harmful. I believe I read that it may negate many of the beneficial effects of docosahexaenoic acid.

Source?

Additionally, I would expect that that supplement regimen would cause severe confusion and blunting of cognitive abilities. (temporary of course... probably)

With the exception of theanine, it was fine. Theanine at >=1000mg has a distinct benzo/GHB-like effect on cognition. Quite relaxing, but I can't be taking GABAergics any more.

 

[invisiroll420]

watch out with this Janus Jopplin most likely died from this it says she choked on her food while being on heroin, idk bout u guys but that shit makes it extremely hard to swallow food or drink. But i have had dysphonia where i had a dopoff tube in my face to my diwadinum so they could put me on liquid food

 

[vecktor]

600mg elemental Mg is perfectly safe, AFAIK. Theanine has been demonstrated entirely non-toxic in mega doses, at least in rats. Rhodiola too has a good safety profile.

You're right -- it probably isn't wise to take such excessive doses, but I wasn't in any sort of danger.



Source?



With the exception of theanine, it was fine. Theanine at >=1000mg has a distinct benzo/GHB-like effect on cognition. Quite relaxing, but I can't be taking GABAergics any more.

elemental magnesium is perfectly safe if a bit flammable, I imagine it probably made a lot hydrogen on contact with stomach acid, perhaps high pitched burps...

 

[psychedelic food]

With the exception of Taurine, I have tried all of those. They don't work for me very well at all.

I don't know how wise it is, by the way, to take that much magnesium, rhodiola, and l-theanine. The eicosapentaenoic aid, too, isn't particularly beneficial if not quite harmful. I believe I read that it may negate many of the beneficial effects of docosahexaenoic acid.

Additionally, I would expect that that supplement regimen would cause severe confusion and blunting of cognitive abilities. (temporary of course... probably)


Leungkachong-

What I meant was merely that simple schizophrenia, unlike paranoid, hebephrenic or catatonic schizophrenia, seems to be a superfluous clinical or diagnostic entity, since in most cases a person with a diagnosis of simple schizophrenia could just as readily obtain a diagnosis of dysthymia or melancholic major depression. There are cases of Schizophrenia, I believe, (or at least Schizophreniform pathologies) where a decrease in brain volume and an enlargement of the ventricles is not observed. Simple schizophrenia appears to be such a sort of Schizophrenia. In that sense, it is perhaps a condition indistinguishable from dysthymia or perhaps major depressive disorder aetiologically. Although, as you mention, either of the latter terms may very well subsume dozens of different aetiologies.

I have experienced plenty of extremely traumatic events.

I never said that all of those disorders I listed were neurostructurally or neurochemically distinct.

Ya man thats exactly what i experience all day everyday. Im just used to it by now. Its nice to know that someone else can relate. Ive had some traumatic events as well. What i think it is is that when we experience such intense traumatic emotion our brains just shut off all emotion, sort of like a defense mechanism. Ive done some research and it seems to be caused by too many endogenous opioids. Which makes sense as opiates can make you apathetic and emotionless. Ive also noticed i have an increased pain threshold. Opiates cannabis and alcohol all stimulate opiate receptors. Im trying to get my hands on some opiate blockers hopefully that might help. Right now im addicted to cigs and klonopin both of which make me more numb and the klonopin has started to make me aggressive at times.

Also im sure youve tried it but MDMA completely kills my numbness for up to two weeks and a good candy flip will take it away for months.

 

[bob123]

there is no such thing dont be crazy

 

[Dxmmonster]

labeling yourself with all these disorders is not going to help you.
You need a healthy lifestyle. Something emotionaly stimulating. Anti depressants usually make people emotionaly numb. Slowly wean yourself off the anti-depressants and you should be back to normal.

 

[monstanoodle]

Some Antidepressants do make you feel emotionally numb, and sometimes that's better than being horribly depressed all the time. But others really do provide a lift from the gloom. It's all about finding the right one.
You could be suffering from depression. I noticed that when mine began, I would smoke weed and it would bring about some nasty dysphoria, and eventually panic attacks. Benzos can also exasperate depression.
Maybe see a doctor and talk it through with them.

(p.s. Forgive me if you're already on an Antidep, but I didn't see it mentioned so assumed you weren't.)