DXM and SSRI's

[Crankinit]

Wasn't sure if this should go into OD or here, but I figured since it primarily concerns DXM, I'd find more people knowledgeable in that area in this section of the forum.

Anyway I'm a regular opiate user, and take DXM in low doses with my opiates because it works well both as a potentiator and to slow the buildup of tolerance. Never more than 60mg or so, once a day.

2 days ago, after some extensive discussion, I agreed with my doctor to try a course of sertraline (zoloft) for insomnia and concentration issues I've been having lately, the dose is low, only 25mg at the moment. I didn't realize at the time that DXM and SSRI's are actually contraindicated due to the potential for serotonin syndrome.

My question is, is serotonin syndrome still a risk at sub-hallucinogenic doses? Will I be safe to take 60mg, once a day? I know the stock harm reduction answer is 'dont do it,' but realistically, is it likely to cause a problem, considering 60mg is only twice the medical dose and well below the recreational dose.

 

[pharmakos]

just want to qualify the following by pointing out that i am in no way an expert, however...

i could see it becoming a problem with chronic use, since DXM will build up in your system when you use it regularly... but any problems would probably be slow to arrive. you're not gonna end up in the emergency room if you dose how you describe, but if you start to feel pretty shitty after a few days/a week or two, then this might be the problem.

p.s. the chance of there being NO complications whatsoever is also pretty high too, i would think.