Drugs that have caloric value

[SpiralusSancti]

Quite caloric is definately a stretch. Fatty acids have 9 kilocalories per gram, so assuming that ghb is as caloric as any other fat it's not going to give you even the calories of a cheeseburger with a pretty debauched night.

Well quite caloric for a drug. I assumed that certain salt might in fact add more calories than GHB itself. But got to admit it looks caloric in pure form lol. I don’t think GHB Na or Mg can have 9 kilocalories per gram but maybe in form of some salt it’s possible. And 100 calories on an empty stomach in 2 – 3 “bites” is still better than nothing, same like coffee in the morning with just a bit of milk isn’t same as black without milk or sugar.

 

[ChemicallyEnhanced]

None apart from alcohol, unless you count edibles but still it's not the actual DRUG that has the calories.
You can somewhat side-step the alcohol calories by using GHB instead (not that I'd recommend it), that's what I did when I was anorexic and I've heard bodybuilders do the same thing (and didn't the strippers in Magic Mike also do that?...uh, not that I've seen it)

 

[ecstacylover]

Oxidizing GHB to succinate gives 2 equiv. of NADH in addition to the energy (1 NADH+1 FADH2) obtained from succinate metabolism to oxaloacetate. In theory, that's about 9 ATP for every molecule of GHB, which makes it about half as energetic as glucose by weight.

Drugs that are proteins are rare. Venoms and toxins not so much.

And serotonin, I'm almost positive isn’t caloric in a kontekst talked here so I assume neither is any of the tryptamines.

There's evidence that dopamine metabolism by monoamine oxidase is coupled to the electron transport chain in dopaminergic neurons, which contributes to their energy supply. Just speculating, but serotonin neurons might conserve energy in a similar manner—namely, by coupling serotonin oxidation to ATP production.