I think the body load is actually the same as the body high but handled differently for some reason. I know someone who just does not respond well to that aspect of it, while others consider 2C-B to be free of side-effect or bodyload.
About future drugs in general, if we can include nootropics like the racetams which are not psychoactive in a classical way but rather enhance sobriety, but also cognition and other faculties: I was just discussing thiabds with my friend/housemate yesterday. He was watching the movie Limitless and also mentioned having quit his Ritalin medication which was going well but there is still use for something to help with attention.
I have a small quantity of aniracetam and when I tried it a while ago, I felt a bit like what happened with the guy when he took that drug in Limitless. Everything just turned HD and lights became brighter and nicer and sound more crisp and sharp but I was able to process all of that much more easily and better which relaxed me. Of course in the movie it's much more of a wonderdrug, and I did not become a genius or something. Still, it's all a bit "futuristic" to me that this exists.
Other things that would be nice in the future are a preparation of NBOMe-like compounds that become more and more 5-HT2A selective but maybe combined with another compound that attenuates the effect beyond a certain point creating a ceiling effect. If the action is truly selective and the ceiling effect really works the result would be as purely psychedelic as possible without being dangerous. Seems like nice theory.
I think there are examples of drugs that self-attenuate like L-theanine and the mix of chemicals in cannabis. In this respect a lot of synthetic cannabinoids are a step back instead of a step forward in the sense that the self-attenuation is lost and there is a bigger potential for overdosing (with something like JWH-018 ) where cannabis seems to be much safer.
