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Misc Dosing guidelines for harm reduction should be backed by more transparent and statistically robust methods, IMO. So, I created my own.

sernyl

PsyAI Developer
Staff member
Joined
Dec 26, 2022
Messages
6
Hi, I'm sernyl, data scientist and pharmaco-enthusiast. I've been involved in a number of harm reduction projects in recent years (https://sojourns.io, https://psyai.chat -- more prominent ones).

I've recently made my dose guideline project publicly available: https://drug.dose.tips; the aim is to provide and alternative source of 'ground truth' with respect to dose categories defined on a per-drug basis (i.e. What is a 'Threshold'? What is a 'Common' range?).

The derivation is entirely statistics-based and explained thoroughly in this document. The dataset consists of scraped dose data (from erowid.org, all ~42k reports posted there), and was also made public (click here).

Any and all feedback is welcome. Thank you for reading my post.

Love and Light,

- sernyl :]
 
I agree with your methamphetamine dosage ranges entirely, and offer you some praise on your conservative recommendations which I don't see advised nearly enough to new users and instead see recklessly high dosages recommended by users with extreme tolerances, particularly on other platforms.

Contrary to what I've seen repeated online, fatality by methamphetamine overdose is very real, very possible, and dosing need not be nearly as high I see people self reporting daily.

Manage tolerance, and you can maintain a sub 70mg usage and still get pretty well spun for a whole day and night

Seeing people IVing 500mg or hotrailing full grams makes my stomach squirm.
 
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@Methamphetanonymous I appreciate your feedback, and I should add that the team behind Erowid.org deserves most of that strongly positive sentiment, as due credit for their meticulous dose annotation efforts. There wouldn't have been any patterns to observe without the data they've collected over the decades. :]
 
Great tool.

One thing that I wanted to point out is that the dosages for ethanol are too vague. It provides general ml guidelines but does not account for ABV%. The difference between drinking a Corona Light (3.2%) and a double IPA (~9%) is extreme. Alcohol also has significantly different levels of effect between genders and other biological factors (BMI, age, etc). That may be difficult if not impossible to work into the output, but I would maybe consider calculating the standardized "alcohol unit" first, then provide ml guideline dosage from there.

I've always used this tool to calculate precisely how much alcohol I am ingesting: https://rethinkingdrinking.niaaa.nih.gov/tools/calculators/drink-size-calculator

I suppose alcohol is probably going to be one of the least utilized portions of the data, but just my 2 cents.

:multicolorheadbang:Thank you for your work.
 
I should probably remove alcohol from the list altogether, since it's a somewhat different beast. :]
I agree. It's too complicated and very subjective. Plus, most people unfortunately don't practice harm reduction with it anyways.
 
Yesterday in the discord PSY AI refused to write me a poem about doing meth and G with grindr femboys. I almost tagged you, sernyl.

But nah, PsyAI is great. I use it all the time for shenanigans as well as legitimate harm reduction questions. It owns.
 
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