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BDD Moderators: Keif’ Richards
Does Tramadol raise opiate tolerance much?
- Thread starter Soylent
- Start date
pillboxskid
Bluelighter
- Joined
- Oct 21, 2012
- Messages
- 111
Varies and depends on which other opiates your reffering 2.But i,ve never herd of blocking the effects should,nt be a problem. But be safe and get use to codeine first dont leap baby steps when dabbling in opiates for your own saftey!!!!
whippa craka
Bluelighter
This chart will surely help you out alot:
http://en.wikipedia.org/wiki/Opioid_receptor#Major_subtypes
It will block effects of other opiates far less any other opioid antagonist would.
http://en.wikipedia.org/wiki/Opioid_receptor#Major_subtypes
It will block effects of other opiates far less any other opioid antagonist would.
I don't understand the wikipedia link there, what's the connection wit the thread?
Anyway, I have found tramadol does not raise tolerance much with respect to other agonists. Another thing I've found that tolerance to regular opioids can be somewhat higher than the "baseline", but still the tolerance to tramadol is low. In my experience, tramadol vs. other opioids are quite different kind of drugs with not so much of a cross tolerance as one would expect. Codeine does not block anything, it just adds to the high.
Anyway, I have found tramadol does not raise tolerance much with respect to other agonists. Another thing I've found that tolerance to regular opioids can be somewhat higher than the "baseline", but still the tolerance to tramadol is low. In my experience, tramadol vs. other opioids are quite different kind of drugs with not so much of a cross tolerance as one would expect. Codeine does not block anything, it just adds to the high.
Swimmingdancer
Bluelight Crew
Well it's all relative and depends on how much tramadol you take and how often you take it. It can raise your tolerance to other opioids. How "much" entirely depends on how much tramadol you use and what other opioids you compare it to.
As for "blocking" effects, what happens is that if you take an opioid and then take another opioid before the other has fully worn off it can lessen the effects of the second opioid. This also depends on what opioid it is, how much you take and how close you take them together. If you take codeine and then take another opioid 24 hrs later I really doubt it would lessen the effects of the second opioid.
As for "blocking" effects, what happens is that if you take an opioid and then take another opioid before the other has fully worn off it can lessen the effects of the second opioid. This also depends on what opioid it is, how much you take and how close you take them together. If you take codeine and then take another opioid 24 hrs later I really doubt it would lessen the effects of the second opioid.